F. Van-den-hoogen, D. Khanna, and J. Fransen, 2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative, Annals of the Rheumatic Diseases, vol.62, issue.(Suppl), pp.1747-55, 2013.
DOI : 10.1002/art.27580

P. Abraham, J. Picquet, and B. Vielle, Transcutaneous Oxygen Pressure Measurements on the Buttocks During Exercise to Detect Proximal Arterial Ischemia: Comparison With Arteriography, Circulation, vol.107, issue.14, pp.1896-900, 2003.
DOI : 10.1161/01.CIR.0000060500.60646.E0

E. Hachulla, P. Hatron, and P. Carpentier, Efficacy of sildenafil on ischaemic digital ulcer healing in systemic sclerosis: the placebo-controlled SEDUCE study, Annals of the Rheumatic Diseases, vol.353, issue.6, pp.1009-1024, 2016.
DOI : 10.1056/NEJMoa050010

URL : https://hal.archives-ouvertes.fr/hal-01466199

P. Youssef, T. Brama, and H. Englert, Limited scleroderma is associated with increased prevalence of macrovascular disease, J Rheumatol, vol.22, pp.469-72, 1995.

J. Olin and B. Sealove, Peripheral Artery Disease: Current Insight Into the Disease and Its Diagnosis and Management, Mayo Clinic Proceedings, vol.85, issue.7, pp.678-92, 2010.
DOI : 10.4065/mcp.2010.0133

M. Roustit, S. Blaise, and Y. Allanore, Phosphodiesterase-5 inhibitors for the treatment of secondary Raynaud's phenomenon: systematic review and meta-analysis of randomised trials, Annals of the Rheumatic Diseases, vol.69, issue.Suppl 10, pp.1696-1705, 2013.
DOI : 10.1136/ard.2009.107706

D. Alves, P. Da-motta, and T. Romero, NO/cGMP production is important for the endogenous peripheral control of hyperalgesia during inflammation, Nitric Oxide, vol.28, pp.8-13, 2013.
DOI : 10.1016/j.niox.2012.09.001

H. Lee, W. Kim, and J. Choi, Roles of adenosine receptor subtypes on the antinociceptive effect of sildenafil in rat spinal cord, Neuroscience Letters, vol.480, issue.3, pp.182-187, 2010.
DOI : 10.1016/j.neulet.2010.06.025

K. Serafim, S. Navarro, and A. Zarpelon, Bosentan, a mixed endothelin receptor antagonist, inhibits superoxide anion-induced pain and inflammation in mice, Naunyn-Schmiedeberg's Archives of Pharmacology, vol.90, issue.Suppl 5, pp.1211-1232, 2015.
DOI : 10.1139/y11-116

C. Denton, J. Pope, and H. Peter, Long-term effects of bosentan on quality of life, survival, safety and tolerability in pulmonary arterial hypertension related to connective tissue diseases, Annals of the Rheumatic Diseases, vol.67, issue.9, pp.1222-1230, 2008.
DOI : 10.1136/ard.2007.079921

D. Haro, J. Bleda, S. Varela, and C. , Effect of Bosentan on Claudication Distance and Endothelium-Dependent Vasodilation in Hispanic Patients With Peripheral Arterial Disease, The American Journal of Cardiology, vol.117, issue.2, pp.295-301, 2016.
DOI : 10.1016/j.amjcard.2015.10.032

A. Gardner and E. Poehlman, Exercise Rehabilitation Programs for the Treatment of Claudication Pain, JAMA, vol.274, issue.12, pp.975-80, 1995.
DOI : 10.1001/jama.1995.03530120067043

A. Pyriochou, Z. Zhou, and V. Koika, The phosphodiesterase 5 inhibitor sildenafil stimulates angiogenesis through a protein kinase G/MAPK pathway, Journal of Cellular Physiology, vol.99, issue.1, pp.197-204, 2007.
DOI : 10.2754/avb200372020273

S. Koneru, V. Penumathsa, S. Thirunavukkarasu, and M. , Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF/angiopoietin-1, Journal of Cellular and Molecular Medicine, vol.57, issue.6b, pp.2651-64, 2008.
DOI : 10.1203/01.PDR.0000147736.27672.15

E. Romano, S. Bellando-randone, and M. Manetti, Bosentan blocks the antiangiogenic effects of sera from systemic sclerosis patients: an in vitro study, Clin Exp Rheumatol, vol.33, pp.148-52, 2015.