Palladium-Catalyzed Regioselective Direct Arylation of Benzofurazans at the C-4 Position

Abstract : The palladium-catalyzed direct arylation of benzofurazans with aryl bromides to access 4-ary-lbenzofurazans proceeds in moderate-to-high yields using phosphine-free palladium acetate as the catalyst and potassium acetate as an inexpensive base. A wide variety of (hetero) aryl bromides, including bromopyridine and bromothiophene derivatives has been successfully employed. Palladium-catalyzed one-pot C-4, C-7-diarylation of benzofurazan was also achieved using a larger amount of aryl bromide. Moreover, the derivatization of 4-arylbenzofurazans into 4-arylquinaxolines is also reported.
Type de document :
Article dans une revue
Advanced Synthesis and Catalysis, Wiley-VCH Verlag, 2017, 359 (14), pp.2448-2456. 〈10.1002/adsc.201700435〉
Liste complète des métadonnées

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01578528
Contributeur : Laurent Jonchère <>
Soumis le : lundi 11 septembre 2017 - 15:00:12
Dernière modification le : vendredi 25 mai 2018 - 01:27:35

Identifiants

Citation

Imane Idris, Fazia Derridj, Jean-François Soule, Henri Doucet. Palladium-Catalyzed Regioselective Direct Arylation of Benzofurazans at the C-4 Position. Advanced Synthesis and Catalysis, Wiley-VCH Verlag, 2017, 359 (14), pp.2448-2456. 〈10.1002/adsc.201700435〉. 〈hal-01578528〉

Partager

Métriques

Consultations de la notice

67

Téléchargements de fichiers

18