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Microwave-assisted practical synthesis of 4-imino-3-phenyl-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thione derivatives and exploration of their biological activities

Abstract : The synthesis of a series of new 4-imino-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thiones 6(a-f) without substituent in C-5 position using microwave dielectric heating is reported. These new compounds were obtained in three steps with good overall yields (21-50%). _figure presented_.
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01581215
Contributor : Laurent Jonchère <>
Submitted on : Monday, September 4, 2017 - 2:38:31 PM
Last modification on : Thursday, July 30, 2020 - 3:13:37 AM

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A. Bouattour, M. Fakhfakh, S. Abid, L. Paquin, Ronan Le Guével, et al.. Microwave-assisted practical synthesis of 4-imino-3-phenyl-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thione derivatives and exploration of their biological activities. ARKIVOC - Online Journal of Organic Chemistry, Arkat USA Inc, 2017, 2017 (4), pp.291--302. ⟨10.24820/ark.5550190.p010.040⟩. ⟨hal-01581215⟩

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