Echo-Doppler estimation of left ventricular filling pressure: results of themulticentre EACVI Euro-Filling study

Abstract : Aims The present Euro-Filling report aimed at comparing the diagnostic accuracy of the 2009 and 2016 echocardiographic grading algorithms for predicting invasively measured left ventricular filling pressure (LVFP). Method and results A total of 159 patients who underwent simultaneous evaluation of echo estimates of LVFP and invasive measurements of LV end-diastolic pressure (LVEDP) were enrolled at nine EACVI centres. Thirty-nine (25%) patients had a reduced LV ejection fraction (< 50%), 77 (64%) were in NYHA >= II, and 85 (53%) had coronary artery disease. Sixty-four (40%) patients had elevated LVEDP (>= 15 mmHg). Taken individually, all echocardiographic Doppler estimates of LVFP (E/A, E/e', left atrial volume, tricuspid regurgitation jet velocity) were marginally correlated with LVEDP. By using the 2016 recommendations, 65% of patients with normal non-invasive estimate of LVFP had normal LVEDP, while 79% of those with elevated non-invasive LVFP had elevated invasive LVEDP. By using 2009 recommendations, 68% of the patients with normal non-invasive LVFP had normal LVEDP, while 55% of those with elevated non-invasive LVFP had elevated LVEDP. The 2016 recommendations (sensitivity 75%, specificity 74%, positive predictive value 39%, negative predictive value 93%, AUC 0.78) identified slightly better patients with elevated invasive LVEDP (>= 15 mmHg) as compared with the 2009 recommendations (sensitivity 43%, specificity 75%, positive predictive value 49%, negative predictive value 71%, AUC 0.68). Conclusion The present Euro-Filling study demonstrates that the new 2016 recommendations for assessing LVFP noninvasively are fairly reliable and clinically useful, as well as superior to the 2009 recommendations in estimating invasive LVEDP.
Type de document :
Article dans une revue
European Heart Journal - Cardiovascular Imaging, Oxford UP, 2017, 18 (9), pp.961-968. 〈10.1093/ehjci/jex067〉
Liste complète des métadonnées

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01617574
Contributeur : Laurent Jonchère <>
Soumis le : lundi 16 octobre 2017 - 16:59:51
Dernière modification le : jeudi 18 janvier 2018 - 01:33:51

Identifiants

Collections

Citation

Patrizio Lancellotti, Maurizio Galderisi, Thor Edvardsen, Erwan Donal, Georg Goliasch, et al.. Echo-Doppler estimation of left ventricular filling pressure: results of themulticentre EACVI Euro-Filling study. European Heart Journal - Cardiovascular Imaging, Oxford UP, 2017, 18 (9), pp.961-968. 〈10.1093/ehjci/jex067〉. 〈hal-01617574〉

Partager

Métriques

Consultations de la notice

44