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Journal articles
Rational and design of EuroCRT: an international observational study on multi-modality imaging and cardiac resynchronization therapy
Erwan Donal
1, 2, 3, *
Victoria Delgado
Julien Magne
4, 5
Chiara Bucciarelli-Ducci
Christophe Leclercq
2, 6, 1
Bernard Cosyns
Marta Sitges
7
Thor Edvardsen
8
Elif Sade
Ivan Stankovic
Eustachio Agricola
Maurizio Galderisi
9
Patrizio Lancellotti
10
Alfredo Hernandez
2
Sven Plein
Denisa Muraru
11
Ehud Schwammenthal
Gerhard Hindricks
Bogdan A. Popescu
Gilbert Habib
2
*
Corresponding author
Erwan Donal 1, 2, 3
Correspondent author
Victoria Delgado
Author
Julien Magne 4, 5
Author
Chiara Bucciarelli-Ducci
Author
Christophe Leclercq 2, 6, 1
Author
Bernard Cosyns
Author
Marta Sitges 7
Author
Thor Edvardsen 8
Author
1
CIC-IT Rennes (2 rue Henri Le Guilloux, 35033 Rennes Cedex 9 - France)
- Hôpital Pontchaillou (France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : CIC804 (101, rue de Tolbiac, 75013 Paris - France)
2
LTSI - Laboratoire Traitement du Signal et de l'Image (Campus Universitaire de Beaulieu - Bât 22 - 35042 Rennes - France)
- UR1 - Université de Rennes 1 (2 rue du Thabor - CS 46510 - 35065 Rennes cedex - France)
- UNIV-RENNES - Université de Rennes (France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : U1099 (101, rue de Tolbiac, 75013 Paris - France)
3
CHU Pontchaillou [Rennes] (2 Rue Henri le Guilloux, 35000 Rennes - France)
4
NET - Neuroépidémiologie Tropicale (Université de Limoges - Faculté de Médecine - 2 rue du Dr Marcland 87025 Limoges - France)
- GEIST - Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (Université de Limoges - Faculté de Médecine - 2 rue du Dr Marcland 87025 Limoges cedex - France)
- UNILIM - Université de Limoges (33 rue François Mitterrand BP23204 87032 Limoges - France)
- CHU Limoges (Centre Hospitalier Universitaire Dupuytren - 2 avenue Martin Luther King 87042 LIMOGES - France)
- Institut d'Epidémiologie Neurologique et de Neurologie Tropicale (France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : U1094 (101, rue de Tolbiac, 75013 Paris - France)
5
Service de cardiologie [CHU Limoges] (Centre Universitaire Dupuytren 2 avenue martin Luther-King 87042 Limoges cedex - France)
- CHU Limoges (Centre Hospitalier Universitaire Dupuytren - 2 avenue Martin Luther King 87042 LIMOGES - France)
6
Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes] (CHU Rennes, 2 Rue Henri le Guilloux, 35000 Rennes - France)
- CHU Pontchaillou [Rennes] (2 Rue Henri le Guilloux, 35000 Rennes - France)
7
Cardiology Department, Thorax Clinic Institute, Hospital Cliınic, Institut d'Investigacions Biomèdiques [Barcelona] (Spain)
- UB - Universitat de Barcelona (Gran Via de les Corts Catalanes, 585, 08007 Barcelona - Spain)
8
Oslo University Hospital [Oslo] (Kirkeveien 166, 0450 Oslo - Norway)
9
Università degli studi di Napoli Federico II (Corso Umberto I 40 - 80138 Napoli - Italy)
10
GIGA-Research - Groupe Interdisciplinaire de Génoprotéomique Appliquée (Avenue de l'Hôpital 1, 4000 Sart-Tilman - Belgium)
- Université de Liège (Place du 20-Août, 7 4000 Liège - Belgium)
11
Universita degli Studi di Padova (Via 8 Febbraio 2, 35122 Padova - Italy)
Abstract : Aims: Assessment of left ventricular (LV) volumes and ejection fraction (LVEF) with cardiac imaging is important in the selection of patients for cardiac resynchronization therapy (CRT). Several observational studies have explored the role of imaging-derived LV dyssynchrony parameters to predict the response to CRT, but have yielded inconsistent results, precluding the inclusion of imaging-derived LV dyssynchrony parameters in current guidelines for selection of patients for CRT. Methods: The EuroCRT is a large European multicentre prospective observational study led by the European Association of Cardiovascular Imaging. We aim to explore if combing the value of cardiac magnetic resonance (CMR) and echocardiography could be beneficial for selecting heart failure patients for CRT in terms of improvement in long-term survival, clinical symptoms, LV function, and volumes. Speckle tracking echocardiography will be used to assess LV dyssynchrony and wasted cardiac work whereas myocardial scar will be assessed with late gadolinium contrast enhanced CMR. All data will be measured in core laboratories. The study will be conducted in European centres with known expertise in both CRT and multimodality cardiac imaging.
Document type :
Journal articles
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Complete list of metadata
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01617888
Contributor : Laurent Jonchère Connect in order to contact the contributor
Submitted on : Tuesday, October 17, 2017 - 11:23:06 AM
Last modification on : Tuesday, November 23, 2021 - 2:34:11 PM
Contributor : Laurent Jonchère Connect in order to contact the contributor
Submitted on : Tuesday, October 17, 2017 - 11:23:06 AM
Last modification on : Tuesday, November 23, 2021 - 2:34:11 PM
Identifiers
- HAL Id : hal-01617888, version 1
- DOI : 10.1093/ehjci/jex021
- PUBMED : 28329299
Collections
UNIV-RENNES1 | CIC | LTSI | GEIST | UNILIM | NET | BIOSIT | UR1-MATH-STIC | UR1-UFR-SVE | UNIV-RENNES | POLITIQUES-PUBLIQUES | UR1-BIO-SA | UR1-MATH-NUM
Citation
Erwan Donal, Victoria Delgado, Julien Magne, Chiara Bucciarelli-Ducci, Christophe Leclercq, et al.. Rational and design of EuroCRT: an international observational study on multi-modality imaging and cardiac resynchronization therapy. European Heart Journal - Cardiovascular Imaging, Oxford UP, 2017, 18 (10), pp.1120-1127. ⟨10.1093/ehjci/jex021⟩. ⟨hal-01617888⟩
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