Full Sequencing and Genomic Analysis of Three emm75 Group A Streptococcus Strains Recovered in the Course of an Epidemiological Shift in French Brittany

Aude Rochefort (1, 2) , Sarrah Boukthir (1, 3, 2) , Séverine Moullec (1, 2) , Alexandra Meygret (3) , Yahia Adnani (1, 2) , Dominique Lavenier (4) , Ahmad Faili (1, 2) , Samer Kayal (1, 3, 2)

1 CIC - Centre d'Investigation Clinique [Rennes]
2 GeRMO - Genomic and Resistance of Opportunistic Microorganisms
3 Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
4 GenScale - Scalable, Optimized and Parallel Algorithms for Genomics

While the incidence and invasiveness of type 75 group A (GAS) infections increased in French Brittany during 2013, we sequenced and analyzed the genomes of three independent strains isolated in 2009, 2012, and 2014, respectively. In this short-term evolution, genomic analysis evidenced mainly the integration of new phages encoding virulence factors.

Domaines: Génomique, Transcriptomique et Protéomique [q-bio.GN]; Bactériologie

Aude Rochefort, Sarrah Boukthir, Séverine Moullec, Alexandra Meygret, Yahia Adnani, et al.. Full Sequencing and Genomic Analysis of Three emm75 Group A Streptococcus Strains Recovered in the Course of an Epidemiological Shift in French Brittany. Genome Announcements, 2017, 5 (39), pp.e00957. ⟨10.1128/genomeA.00957-17⟩. ⟨hal-01617890⟩