Skip to Main content Skip to Navigation
Journal articles

Ruthenium Phosphine-Pyridone Catalyzed Cross-Coupling of Alcohols To form α-Alkylated Ketones

Abstract : An efficient and green route to access diverse functionalized ketones via dehydrogenative-dehydrative cross-coupling of primary and secondary alcohols is demonstrated. Selective and tunable formation of ketones or alcohols is catalyzed by a recently developed proton responsive ruthenium phosphine-pyridone complex. Light alcohols such as ethanol could be used as alkylating agents in this methodology. Moreover, selective tandem double alkylation of isopropanol is achieved by sequential addition of different alcohols.
Document type :
Journal articles
Complete list of metadatas

Cited literature [3 references]  Display  Hide  Download

https://hal-univ-rennes1.archives-ouvertes.fr/hal-01617951
Contributor : Laurent Jonchère <>
Submitted on : Monday, November 13, 2017 - 11:35:02 AM
Last modification on : Thursday, March 5, 2020 - 2:07:23 PM
Long-term archiving on: : Wednesday, February 14, 2018 - 1:14:17 PM

File

Ruthenium Phosphine-Pyridone_a...
Files produced by the author(s)

Identifiers

Citation

Apurba R. Sahoo, Gummidi Lalitha, V. Murugesh, Christian Bruneau, Gangavaram V. M. Sharma, et al.. Ruthenium Phosphine-Pyridone Catalyzed Cross-Coupling of Alcohols To form α-Alkylated Ketones. Journal of Organic Chemistry, American Chemical Society, 2017, 82 (19), pp.10727-10731. ⟨10.1021/acs.joc.7b02042⟩. ⟨hal-01617951⟩

Share

Metrics

Record views

184

Files downloads

231