Malignant Gliomas in Adults, New England Journal of Medicine, vol.359, issue.5, pp.492-507, 2008. ,
DOI : 10.1056/NEJMra0708126
The treatment of glioblastomas: A systematic update on clinical Phase III trials, Critical Reviews in Oncology/Hematology, vol.87, issue.3, pp.265-82, 2013. ,
DOI : 10.1016/j.critrevonc.2013.01.007
Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology, Cancer Research, vol.69, issue.23, pp.9065-72, 2009. ,
DOI : 10.1158/0008-5472.CAN-09-2307
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1, Cancer Cell, vol.17, issue.1, pp.98-110, 2010. ,
DOI : 10.1016/j.ccr.2009.12.020
Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain, Acta Neuropathologica, vol.360, issue.Suppl 1, 2015. ,
DOI : 10.1056/NEJMoa0808710
Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma, Cancer Cell, vol.17, issue.5, pp.510-532, 2010. ,
DOI : 10.1016/j.ccr.2010.03.017
URL : https://hal.archives-ouvertes.fr/hal-01201573
The Somatic Genomic Landscape of Glioblastoma, Cell, vol.155, issue.2, pp.462-77, 2013. ,
DOI : 10.1016/j.cell.2013.09.034
Molecular neuro-oncology in clinical practice: a new horizon, The Lancet Oncology, vol.14, issue.9, pp.370-379, 2013. ,
DOI : 10.1016/S1470-2045(13)70168-2
Epigenetics in Cancer, New England Journal of Medicine, vol.358, issue.11, pp.1148-59, 2008. ,
DOI : 10.1056/NEJMra072067
Cancer epigenetics reaches mainstream oncology, Nature Medicine, vol.18, pp.330-339, 2011. ,
DOI : 10.1038/sj.leu.2403388
Large hypomethylated blocks as a universal defining epigenetic alteration in human solid tumors, Genome Medicine, vol.12, issue.8, p.61, 2014. ,
DOI : 10.1038/nrd4154
A decade of exploring the cancer epigenome ??? biological and translational implications, Nature Reviews Cancer, vol.9, issue.16, pp.726-760, 2011. ,
DOI : 10.1038/nrg2270
Unraveling the Glioma Epigenome-From Molecular Mechanisms to Novel Biomarkers and Therapeutic Targets, Brain Pathology, vol.102, issue.2, pp.619-651, 2011. ,
DOI : 10.1042/BC20100029
DNA methylation profiling in the clinic: applications and challenges, Nature Reviews Genetics, vol.20, issue.10, pp.679-92, 2012. ,
DOI : 10.1186/1476-4598-9-259
DNA methylation in glioblastoma: impact on gene expression and clinical outcome., BMC Genomics, vol.11, issue.1, p.701, 2010. ,
DOI : 10.1186/1471-2164-11-701
URL : https://hal.archives-ouvertes.fr/inserm-00663706
Genome-Wide Methylation Analyses in Glioblastoma Multiforme, PLoS ONE, vol.40, issue.2, p.89376, 2014. ,
DOI : 10.1371/journal.pone.0089376.s006
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma, Cancer Cell, vol.22, issue.4, pp.425-462, 2012. ,
DOI : 10.1016/j.ccr.2012.08.024
Stem Cell???Related ???Self-Renewal??? Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma, Journal of Clinical Oncology, vol.26, issue.18, pp.3015-3039, 2008. ,
DOI : 10.1200/JCO.2007.15.7164
Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are associated with expression of a stem cell related HOX-signature in glioblastoma, Genome Biology, vol.16, issue.1, p.16, 2015. ,
DOI : 10.1038/nature07385
A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function, Journal of Neuroscience, vol.28, issue.1, pp.264-78, 2008. ,
DOI : 10.1523/JNEUROSCI.4178-07.2008
Functional organization of the transcriptome in human brain, Nature Neuroscience, vol.24, issue.11, pp.1271-82, 2008. ,
DOI : 10.1038/nn.2207
Concise Review: MicroRNAs as Modulators of Stem Cells and Angiogenesis, STEM CELLS, vol.59, issue.5, pp.1059-66, 2014. ,
DOI : 10.1016/j.jacc.2012.02.033
Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer, Oncogene, vol.1, issue.6, pp.679-89, 2014. ,
DOI : 10.1038/nprot.2006.47
Modulation of miR-21 signaling by MPS1 in human glioblastoma, Oncotarget, vol.7, issue.33, pp.52912-52927, 2015. ,
DOI : 10.18632/oncotarget.4143
Tumor suppressor miR-34a targets PD-L1 and functions as a potential immunotherapeutic target in acute myeloid leukemia, Cellular Signalling, vol.27, issue.3, pp.443-52, 2015. ,
DOI : 10.1016/j.cellsig.2014.12.003
A double feedback loop mediated by microRNA-23a/27a/24-2 regulates M1 <i>versus</i> M2 macrophage polarization and thus regulates cancer progression, Oncotarget, vol.7, issue.12, pp.13502-13521, 2016. ,
DOI : 10.18632/oncotarget.6284
<i>NOVA1</i> inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal, Oncotarget, vol.7, issue.3, pp.2475-95, 2016. ,
DOI : 10.18632/oncotarget.6542
Epigenetic Silencing of the Tumor Suppressor MicroRNA Hsa-miR-124a Regulates CDK6 Expression and Confers a Poor Prognosis in Acute Lymphoblastic Leukemia, Cancer Research, vol.69, issue.10, pp.4443-53, 2009. ,
DOI : 10.1158/0008-5472.CAN-08-4025
MicroRNA Profiling in Subventricular Zone after Stroke: MiR-124a Regulates Proliferation of Neural Progenitor Cells through Notch Signaling Pathway, PLoS ONE, vol.282, issue.5, p.23461, 2011. ,
DOI : 10.1371/journal.pone.0023461.s004
Dicer1 and miR-219 Are Required for Normal Oligodendrocyte Differentiation and Myelination, Neuron, vol.65, issue.5, pp.597-611, 2010. ,
DOI : 10.1016/j.neuron.2010.01.027
URL : https://doi.org/10.1016/j.neuron.2010.01.027
A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma, New England Journal of Medicine, vol.370, issue.8, pp.699-708, 2014. ,
DOI : 10.1056/NEJMoa1308573
Bevacizumab plus Radiotherapy???Temozolomide for Newly Diagnosed Glioblastoma, New England Journal of Medicine, vol.370, issue.8, pp.709-731, 2014. ,
DOI : 10.1056/NEJMoa1308345
URL : http://umu.diva-portal.org/smash/get/diva2:725879/FULLTEXT01
DNA Methylation As a Clinical Marker in Oncology, Journal of Clinical Oncology, vol.30, issue.20, pp.2566-2574, 2012. ,
DOI : 10.1200/JCO.2012.42.1016
Quantitative cross-validation and content analysis of the 450k DNA methylation array from Illumina, Inc., BMC Research Notes, vol.5, issue.1, p.210, 2012. ,
DOI : 10.1002/path.2495
DNA hypomethylation in cancer cells, Epigenomics, vol.94, issue.2, pp.239-59, 2009. ,
DOI : 10.1073/pnas.94.9.4681
DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter, Human Molecular Genetics, vol.2, issue.22, pp.4299-310, 2011. ,
DOI : 10.1371/journal.pgen.0020160
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina???associated domains, Nature Genetics, vol.12, issue.1, pp.40-46, 2012. ,
DOI : 10.1186/gb-2009-10-7-r79
STRING v9.1: protein-protein interaction networks, with increased coverage and integration, Nucleic Acids Research, vol.37, issue.D1, pp.808-823, 2013. ,
DOI : 10.1093/nar/gkn750
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma, New England Journal of Medicine, vol.352, issue.10, pp.987-96, 2005. ,
DOI : 10.1056/NEJMoa043330
A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data, Bioinformatics, vol.24, issue.2, pp.189-96, 2013. ,
DOI : 10.1186/1471-2105-13-59
Rembrandt: Helping Personalized Medicine Become a Reality through Integrative Translational Research, Molecular Cancer Research, vol.7, issue.2, pp.157-67, 2009. ,
DOI : 10.1158/1541-7786.MCR-08-0435
URL : http://mcr.aacrjournals.org/content/molcanres/7/2/157.full.pdf
Adjusting batch effects in microarray expression data using empirical Bayes methods, Biostatistics, vol.30, issue.4, pp.118-145, 2007. ,
DOI : 10.1093/nar/30.4.e15
Generalized Maximally Selected Statistics, Biometrics, vol.69, issue.4, pp.1263-1272, 2008. ,
DOI : 10.1093/biomet/69.2.297
URL : http://epub.wu.ac.at/1252/1/document.pdf
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles, Proceedings of the National Academy of Sciences, vol.19, issue.18, pp.15545-50, 2005. ,
DOI : 10.1093/bioinformatics/btg363
Statistical Significance of Clustering for High-Dimension, Low???Sample Size Data, Journal of the American Statistical Association, vol.103, issue.483, pp.1281-93, 2008. ,
DOI : 10.1198/016214508000000454
GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers, Genome Biology, vol.12, issue.4, p.41, 2011. ,
DOI : 10.1214/aos/1176344136
Mutational heterogeneity in cancer and the search for new cancer-associated genes, Nature, vol.31, issue.7457, pp.214-222, 2013. ,
DOI : 10.1038/nbt.2514
MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status, Acta Neuropathologica, vol.6, issue.4, pp.547-60, 2012. ,
DOI : 10.1371/journal.pone.0025451