A novel mechanism for activation of Aurora-A kinase by Ajuba, Gene, vol.543, pp.133-139, 2014. ,
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle, Mol. Cell, vol.12, issue.03, pp.392-399, 2003. ,
Zfp207 is a Bub3 binding protein regulating meiotic chromosome alignment in mouse oocytes, Oncotarget, vol.7, pp.30155-30165, 2016. ,
A novel mechanism for activation of the protein kinase Aurora A, Curr. Biol, vol.13, pp.166-166, 2003. ,
TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux, J. Cell Biol, vol.210, pp.373-383, 2015. ,
Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly, J. Biol. Chem, vol.285, pp.35238-35244, 2010. ,
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells, Cell, vol.114, issue.03, pp.642-643, 2003. ,
A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting, Dev. Cell, vol.28, pp.268-281, 2014. ,
RanGTP aids anaphase entry through Ubr5-mediated protein turnover, J. Cell Biol, vol.211, pp.7-18, 2015. ,
Phase transition of spindle-associated protein regulate spindle apparatus assembly, Cell, vol.163, pp.108-122, 2015. ,
Centrosomal protein of 192 kDa (Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation, Proc. Natl. Acad. Sci. USA, vol.107, pp.21022-21027, 2010. ,
The Cep192-organized aurora A-Plk1 cascade is essential for centrosome cycle and bipolar spindle assembly, Mol. Cell, vol.55, pp.578-591, 2014. ,
Human TPX2 is required for targeting Aurora-A kinase to the spindle, J. Cell Biol, vol.158, pp.617-623, 2002. ,
Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation, Cell Cycle, vol.15, pp.413-424, 2016. ,
Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A, Proc. Natl. Acad. Sci. USA, vol.99, pp.15440-15445, 2002. ,
Requirement for Nudel and dynein for assembly of the lamin B spindle matrix, Nat. Cell Biol, vol.11, pp.247-256, 2009. ,
The depletion attraction: an underappreciated force driving cellular organization, J. Cell Biol, vol.175, pp.681-686, 2006. ,
Aurora A kinase (AUR KA) in normal and pathological cell division, Cell. Mol. Life Sci, vol.70, pp.661-687, 2013. ,
The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome, Nat. Cell Biol, vol.7, pp.937-946, 2005. ,
Drosophila Ajuba is not an Aurora-A activator but is required to maintain Aurora-A at the centrosome, J. Cell Sci, vol.124, pp.1156-1166, 2011. ,
Dissecting the role of Aurora A during spindle assembly, EMBO J, vol.27, pp.2567-2579, 2008. ,
Phase separation of signaling molecules promotes T cell receptor signal transduction, Science, vol.352, pp.595-599, 2016. ,
BuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignment, Dev. Cell, vol.28, pp.282-294, 2014. ,
Aurora A kinase-coated beads function as microtubule-organizing centers and enhance RanGTP-induced spindle assembly, Curr. Biol, vol.15, pp.2156-2163, 2005. ,
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly, Nat. Cell Biol, vol.5, pp.242-248, 2003. ,
URL : https://hal.archives-ouvertes.fr/inserm-00966479
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation, Oncogene, vol.19, pp.4906-4916, 2000. ,
Splicing function of mitotic regulators links R-loop-mediated DNA damage to tumor cell killing, J. Cell Biol, vol.209, pp.235-246, 2015. ,
Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2, J. Cell Biol, vol.191, pp.1315-1332, 2010. ,
Aurora A phosphorylates MCAK to control ran-dependent spindle bipolarity, 2008. ,
, Mol. Biol. Cell, vol.19, pp.2752-2765
Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2. eLife. 3:e02667, 2014. ,