W. O. Cooper, M. E. Willy, S. J. Pont, and W. A. Ray, Increasing use of antidepressants in pregnancy, American Journal of Obstetrics and Gynecology, vol.196, issue.6, pp.544-545, 2007.

J. L. Pawluski, J. S. Lonstein, and A. S. Fleming, The Neurobiology of Postpartum Anxiety and Depression, Trends in Neurosciences, vol.40, issue.2, pp.106-120, 2017.
DOI : 10.1016/j.tins.2016.11.009

URL : https://hal.archives-ouvertes.fr/hal-01452985

R. A. Charlton, S. Jordan, A. Pierini, E. Garne, A. J. Neville et al.,

J. , Selective serotonin reuptake inhibitor prescribing before, during and after pregnancy: A population-based study in six European regions, BJOG: An International Journal of Obstetrics & Gynaecology, vol.122, issue.7, pp.1010-1020, 2015.

T. F. Oberlander, W. Warburton, S. Misri, J. Aghajanian, and C. Hertzman, Neonatal Outcomes After Prenatal Exposure to Selective Serotonin Reuptake Inhibitor Antidepressants and Maternal Depression Using Population-Based Linked Health Data, Archives of General Psychiatry, vol.63, issue.8, pp.63-898, 2006.
DOI : 10.1001/archpsyc.63.8.898

P. M. Whitaker-azmitia, M. Druse, P. Walker, and J. M. Lauder, Serotonin as a developmental signal, Behavioural Brain Research, vol.73, issue.1-2, pp.19-29, 1995.
DOI : 10.1016/0166-4328(96)00071-X

J. Kim, K. W. Riggs, S. Misri, N. Kent, T. F. Oberlander et al., Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast-feeding, British Journal of Clinical Pharmacology, vol.36, issue.2, pp.61-155, 2006.
DOI : 10.1016/S0006-3223(01)01197-0

S. Brummelte and L. A. Galea, Postpartum depression: Etiology, treatment and consequences for maternal care, Hormones and Behavior, vol.77, pp.153-166, 2016.
DOI : 10.1016/j.yhbeh.2015.08.008

T. Oberlander, J. A. Gingrich, and M. S. Ansorge, Sustained Neurobehavioral Effects of Exposure to SSRI Antidepressants During Development: Molecular to Clinical Evidence, Clinical Pharmacology & Therapeutics, vol.48, issue.6, pp.672-677, 2009.
DOI : 10.1038/sj.mp.4002007

M. Ellfolk and H. Malm, Risks associated with in utero and lactation exposure to selective serotonin reuptake inhibitors (SSRIs), Reproductive Toxicology, vol.30, issue.2, pp.249-260, 2010.
DOI : 10.1016/j.reprotox.2010.04.015

M. L. Grzeskowiak, A. L. Gilbert, and J. L. Morrison, Investigating Outcomes Following the Use of Selective Serotonin Reuptake Inhibitors for Treating Depression in Pregnancy, Drug Safety, vol.26, issue.6, pp.34-1027, 2011.
DOI : 10.1097/00007691-200412000-00016

M. S. Ansorge, M. Zhou, A. Lira, R. Hen, and J. A. Gingrich, Early-Life Blockade of the 5-HT Transporter Alters Emotional Behavior in Adult Mice, Science, vol.306, issue.5697, pp.306-879, 2004.
DOI : 10.1126/science.1101678

M. Gemmel, E. Bögi, C. Ragan, M. Hazlett, M. Dubovicky et al.,

J. L. Pawluski, Perinatal selective serotonin reuptake inhibitor medication (SSRI) effects on social behaviors, neurodevelopment and the epigenome, Neuroscience & Biobehavioral Reviews, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01619303

S. F. Lisboa, P. E. Oliveira, L. C. Costa, E. J. Venâncio, and E. G. Moreira, , 2007.

, Behavioral evaluation of male and female mice pups exposed to fluoxetine during pregnancy and lactation, Pharmacology, vol.80, issue.1, pp.49-56

D. Maciag, K. L. Simpson, D. Coppinger, Y. Lu, Y. Wang et al.,

, Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry, Neuropsychopharmacology, vol.31, issue.1, pp.47-57

D. Popa, C. Léna, C. Alexandre, and J. Adrien, Lasting Syndrome of Depression Produced by Reduction in Serotonin Uptake during Postnatal Development: Evidence from Sleep, Stress, and Behavior, Journal of Neuroscience, vol.28, issue.14, pp.28-3546, 2008.
DOI : 10.1523/JNEUROSCI.4006-07.2008

C. W. Noorlander, F. F. Ververs, P. G. Nikkels, C. J. Van-echteld, G. H. Visser et al., Modulation of Serotonin Transporter Function during Fetal Development Causes Dilated Heart Cardiomyopathy and Lifelong Behavioral Abnormalities, PLoS ONE, vol.267, issue.7, p.2782, 2008.
DOI : 10.1371/journal.pone.0002782.s001

I. Rayen, H. W. Steinbusch, T. D. Charlier, and J. L. Pawluski, Developmental fluoxetine exposure and prenatal stress alter sexual differentiation of the brain and reproductive behavior in male rat offspring, Psychoneuroendocrinology, vol.38, issue.9, pp.38-1618, 2013.
DOI : 10.1016/j.psyneuen.2013.01.007

URL : https://hal.archives-ouvertes.fr/hal-01122065

F. Boulle, J. L. Pawluski, J. R. Homberg, B. Machiels, Y. Kroeze et al., Developmental fluoxetine exposure increases behavioral despair and alters epigenetic regulation of the hippocampal BDNF gene in adult female offspring, Hormones and Behavior, vol.80, pp.47-57, 2016.
DOI : 10.1016/j.yhbeh.2016.01.017

URL : https://hal.archives-ouvertes.fr/hal-01313750

G. E. Hanley, U. Brain, and T. F. Oberlander, Infant developmental outcomes following prenatal exposure to antidepressants, and maternal depressed mood and positive affect, Early Human Development, vol.89, issue.8, pp.89-519, 2013.
DOI : 10.1016/j.earlhumdev.2012.12.012

T. F. Oberlander, P. Reebye, S. Misri, M. Papsdorf, J. Kim et al., , 2007.

, Externalizing and attentional behaviors in children of depressed mothers treated with a selective serotonin reuptake inhibitor antidepressant during pregnancy, Archives of Pediatrics & Adolescent Medicine, vol.161, issue.1, pp.22-29

W. M. Weikum, U. Brain, C. M. Chau, R. E. Grunau, W. T. Boyce et al., Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age, Frontiers in Cellular Neuroscience, vol.7, pp.1-12, 2013.
DOI : 10.3389/fncel.2013.00180

H. Malm, A. S. Brown, M. Gissler, D. Gyllenberg, S. Hinkka-yli-salomäki et al., Gestational Exposure to Selective Serotonin Reuptake Inhibitors and Offspring Psychiatric Disorders: A National Register-Based Study, Journal of the American Academy of Child & Adolescent Psychiatry, vol.55, issue.5, pp.55-359, 2016.
DOI : 10.1016/j.jaac.2016.02.013

URL : http://europepmc.org/articles/pmc4851729?pdf=render

A. Serretti and L. Mandelli, Antidepressants and Body Weight, The Journal of Clinical Psychiatry, vol.71, issue.10, pp.71-1259, 2010.
DOI : 10.4088/JCP.09r05346blu

T. R. Sampson and S. K. Mazmanian, Control of Brain Development, Function, and Behavior by the Microbiome, Cell Host & Microbe, vol.17, issue.5, pp.565-576, 2015.
DOI : 10.1016/j.chom.2015.04.011

D. Palma, G. Blennerhassett, P. Lu, J. Deng, Y. Park et al., Microbiota and host determinants of behavioural phenotype in maternally separated mice, Nature Communications, vol.5, issue.1, 2015.
DOI : 10.1371/journal.pcbi.1000352

O. 'mahony, S. M. Clarke, G. Borre, Y. E. Dinan, T. G. Cryan et al., Serotonin, tryptophan metabolism and the brain-gut-microbiome axis, Behavioural Brain Research, vol.277, pp.32-48, 2015.

D. P. Guh, W. Zhang, N. Bansback, and Z. Amarsi, , 2009.

, The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis, BMC public health, vol.9, issue.1, p.88

S. Kent, F. Fusco, A. Gray, S. A. Jebb, B. J. Cairns et al., Body mass index and healthcare costs: a systematic literature review of individual participant data studies, Obesity Reviews, vol.363, issue.8, 2017.
DOI : 10.1056/NEJMoa1000367

H. Huang, S. Coleman, J. A. Bridge, K. Yonkers, and W. Katon, A meta-analysis of the relationship between antidepressant use in pregnancy and the risk of preterm birth and low birth weight, General Hospital Psychiatry, vol.36, issue.1, pp.13-18, 2014.
DOI : 10.1016/j.genhosppsych.2013.08.002

K. A. Lattimore, S. M. Donn, N. Kaciroti, A. R. Kemper, C. R. Neal et al.,

, Selective serotonin reuptake inhibitor (SSRI) use during pregnancy and effects on the fetus and newborn: A meta-analysis, Journal of Perinatology, vol.25, issue.9, pp.595-604

L. E. Ross, S. Grigoriadis, L. Mamisashvili, E. H. Vonderporten, M. Roerecke et al., Selected Pregnancy and Delivery Outcomes After Exposure to Antidepressant Medication, JAMA Psychiatry, vol.70, issue.4, pp.436-443, 2013.
DOI : 10.1001/jamapsychiatry.2013.684

C. D. Chambers, K. A. Johnson, L. M. Dick, R. J. Felix, and K. L. Jones, Birth outcomes in pregnant women taking fluoxetine, New England Journal of Medicine, issue.14, pp.335-1010, 1996.
DOI : 10.1097/00006254-199703000-00005

M. Reis and B. Källén, Delivery outcome after maternal use of antidepressant drugs in pregnancy: an update using Swedish data, Psychological Medicine, vol.20, issue.10, pp.40-1723, 2010.
DOI : 10.1002/pds.1462

B. Källén, Neonate Characteristics After Maternal Use of Antidepressants in Late Pregnancy, Archives of Pediatrics & Adolescent Medicine, vol.158, issue.4, pp.312-316, 2004.
DOI : 10.1001/archpedi.158.4.312

A. A. Mamun and M. Mannan, Gestational weight gain in relation to offspring obesity over the life course: a systematic review and bias-adjusted meta-analysis, Obesity Reviews, vol.165, issue.4, pp.338-347, 2014.
DOI : 10.1093/aje/kwk030

L. E. Grzeskowiak, A. L. Gilbert, and J. L. Morrison, Long term impact of prenatal exposure to SSRIs on growth and body weight in childhood: Evidence from animal and human studies, Reproductive Toxicology, vol.34, issue.1, pp.101-109, 2012.
DOI : 10.1016/j.reprotox.2012.03.003

E. E. Accortt, A. C. Cheadle, and C. D. Schetter, Prenatal Depression and Adverse Birth Outcomes: An Updated Systematic Review, Maternal and Child Health Journal, vol.22, issue.3, pp.1306-1337, 2015.
DOI : 10.1093/humrep/del432

URL : http://europepmc.org/articles/pmc4447551?pdf=render

N. K. Grote, J. A. Bridge, A. R. Gavin, J. L. Melville, S. Iyengar et al., , 2010.

, A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction, Archives of General Psychiatry, vol.67, issue.10, pp.1012-1024

S. Grigoriadis, E. H. Vonderporten, L. Mamisashvili, G. Tomlinson, C. L. Dennis et al., The Impact of Maternal Depression During Pregnancy on Perinatal Outcomes, The Journal of Clinical Psychiatry, vol.74, issue.04, pp.321-341, 2013.
DOI : 10.4088/JCP.12r07968

A. Jarde, M. Morais, D. Kingston, R. Giallo, G. M. Macqueen et al., Neonatal Outcomes in Women With Untreated Antenatal Depression Compared With Women Without Depression, JAMA Psychiatry, vol.73, issue.8, pp.73-826, 2016.
DOI : 10.1001/jamapsychiatry.2016.0934

K. Nezvalová-henriksen, O. Spigset, R. E. Brandlistuen, E. Ystrom, G. Koren et al., Effect of prenatal selective serotonin reuptake inhibitor (SSRI) exposure on birthweight and gestational age: a sibling-controlled cohort study, International Journal of Epidemiology, vol.24, issue.1, pp.1-12, 2016.
DOI : 10.5324/nje.v24i1-2.1822

C. V. Vorhees, K. D. Acuff-smith, M. A. Schilling, J. E. Fisher, M. S. Moran et al., A Developmental Neurotoxicity Evaluation of the Effects of Prenatal Exposure to Fluoxetine in Rats, Toxicological Sciences, vol.23, issue.2, pp.194-205, 1994.
DOI : 10.1093/toxsci/23.2.194

K. L. Bairy, S. Madhyastha, K. P. Ashok, I. Bairy, and S. Malini, Developmental and Behavioral Consequences of Prenatal Fluoxetine, Pharmacology, vol.37, issue.1, pp.1-11, 2007.
DOI : 10.1002/tera.1420370303

T. M. Cabrera and G. Battaglia, Delayed decreases in brain 5- hydroxytryptamine2A/2C receptor density and function in male rat progeny following prenatal fluoxetine, Journal of Pharmacology and Experimental Therapeutics, vol.269, issue.2, pp.637-645, 1994.

R. Cagiano, P. Flace, I. Bera, L. Maries, G. Cioca et al., , 2008.

, Neurofunctional effects in rats prenatally exposed to fluoxetine, European Review for Medical and Pharmacological Sciences, vol.12, issue.3, p.137

F. H. Coleman, H. D. Christensen, C. L. Gonzalez, and W. F. Rayburn, Behavioral changes in developing mice after prenatal exposure to paroxetine (Paxil), American Journal of Obstetrics and Gynecology, vol.181, issue.5, pp.181-1166, 1999.
DOI : 10.1016/S0002-9378(99)70102-X

V. A. Da-silva, S. P. Altenburg, L. R. Malheiros, T. G. Thomaz, and . Lindsey, C. J, 1999.

, Postnatal development of rats exposed to fluoxetine or venlafaxine during the third week of pregnancy, Brazilian Journal of Medical and Biological Research, vol.32, issue.1, pp.93-98

B. B. Mcallister, V. Kiryanova, and R. H. Dyck, Behavioural outcomes of perinatal maternal fluoxetine treatment, Neuroscience, vol.226, pp.356-366, 2012.
DOI : 10.1016/j.neuroscience.2012.09.024

J. C. Müller, A. C. Boareto, E. L. Lourenço, R. M. Zaia, and M. F. Kienast,

M. Dalsenter and P. R. , In utero and lactational exposure to fluoxetine in Wistar rats: Pregnancy outcomes and sexual development, Basic & Clinical Pharmacology & Toxicology, vol.113, issue.2, pp.132-140, 2013.

D. L. Van-den-hove, C. E. Blanco, A. Scheepens, L. Desbonnet, A. M. Myint et al., Prenatal Maternal Paroxetine Treatment and Neonatal Mortality in the Rat: A Preliminary Study, Neonatology, vol.186, issue.1, pp.93-52, 2008.
DOI : 10.1001/jama.293.19.2372

M. S. Stanford and J. H. Patton, In utero exposure to fluoxetine HCl increases hematoma frequency at birth, Pharmacology Biochemistry and Behavior, vol.45, issue.4, pp.959-962, 1993.
DOI : 10.1016/0091-3057(93)90147-L

D. Long, N. E. Barry, E. J. Pinelli, C. Wood, G. A. Hardy et al., Antenatal exposure to the selective serotonin reuptake inhibitor fluoxetine leads to postnatal metabolic and endocrine changes associated with type 2 diabetes in Wistar rats, Toxicology and Applied Pharmacology, vol.285, issue.1, pp.32-40, 2015.
DOI : 10.1016/j.taap.2015.03.006

A. H. Santos, M. L. Vieira, N. De-azevedo-camin, J. A. Anselmo-franci, G. S. Ceravolo et al., In utero and lactational exposure to fluoxetine delays puberty onset in female rats offspring, utero and lactational exposure to fluoxetine delays puberty onset in female rats offspring, pp.1-8, 2016.
DOI : 10.1016/j.reprotox.2016.04.006

M. Dubovický, E. Császárová, and Z. Brnoliaková,

, Effect of prenatal administration of venlafaxine on postnatal development of rat offspring, Interdisciplinary Toxicology, vol.5, issue.2, pp.92-97

E. Fornaro, D. Li, J. Pan, and J. Belik, Prenatal Exposure to Fluoxetine Induces Fetal Pulmonary Hypertension in the Rat, American Journal of Respiratory and Critical Care Medicine, vol.176, issue.10, pp.176-1035, 2007.
DOI : 10.1159/000084527

J. Francis-oliveira, B. Ponte, A. P. Barbosa, L. F. Veríssimo, M. V. Gomes et al., Fluoxetine exposure during pregnancy and lactation: Effects on acute stress response and behavior in the novelty-suppressed feeding are age and gender-dependent in rats, Behavioural Brain Research, vol.252, pp.195-203, 2013.
DOI : 10.1016/j.bbr.2013.05.064

M. E. Glover, P. C. Pugh, N. L. Jackson, J. L. Cohen, and A. D. Fant,

M. , Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats, Neuroscience, vol.284, pp.775-797, 2015.

J. D. Pereira, A. Caricati-neto, A. Jurkiewicz, and N. H. Jurkiewicz, Decreased noradrenergic and serotonergic reactivity of vas deferens of newborn rats from mothers treated with the serotonin reuptake inhibitor fluoxetine during pregnancy and breast-feeding, Life Sciences, vol.81, issue.21-22, pp.81-1501, 2007.
DOI : 10.1016/j.lfs.2007.09.012

M. L. Vieira, R. Y. Hamada, N. I. Gonzaga, A. D. Bacchi, M. Barbieri et al.,

&. Gerardin and D. C. , Could maternal exposure to the antidepressants fluoxetine and St, 2013.

, John's Wort induce long-term reproductive effects on male rats?, Reproductive Toxicology, vol.35, pp.102-107

J. L. Morrison, C. Chien, N. Gruber, D. Rurak, and W. Riggs, Fetal behavioural state changes following maternal fluoxetine infusion in sheep, Developmental Brain Research, vol.131, issue.1-2, pp.47-56, 2001.
DOI : 10.1016/S0165-3806(01)00255-3

R. A. Byrd and J. K. Markham, Developmental Toxicology Studies of Fluoxetine Hydrochloride Administered Orally to Rats and Rabbits, Fundamental and Applied Toxicology, vol.22, issue.4, pp.511-518, 1994.
DOI : 10.1006/faat.1994.1058

I. Nulman, J. Rovet, D. E. Stewart, J. Wolpin, P. Pace-asciak et al., Child Development Following Exposure to Tricyclic Antidepressants or Fluoxetine Throughout Fetal Life: A Prospective, Controlled Study, American Journal of Psychiatry, vol.159, issue.11, pp.159-1889, 2002.
DOI : 10.1176/appi.ajp.159.11.1889

C. D. Chambers, P. O. Anderson, R. G. Thomas, L. M. Dick, R. J. Felix et al., Weight Gain in Infants Breastfed by Mothers Who Take Fluoxetine, Pediatrics, vol.104, issue.5, pp.61-61, 1999.
DOI : 10.1542/peds.104.5.e61

A. J. Lewis, M. Galbally, G. Opie, and A. Buist, Exposure to Antidepressant Medication, Australian & New Zealand Journal of Psychiatry, vol.150, issue.4, pp.482-487, 2010.
DOI : 10.1080/00048670903107583

P. Merlob, B. Stahl, and J. Sulkes, Paroxetine during breast-feeding: infant weight gain and maternal adherence to counsel, European Journal of Pediatrics, vol.163, issue.3, pp.135-139, 2004.
DOI : 10.1007/s00431-003-1391-8

L. E. Grzeskowiak, A. L. Gilbert, and J. L. Morrison, Prenatal exposure to selective serotonin reuptake inhibitors and risk of childhood overweight, Journal of Developmental Origins of Health and Disease, vol.269, issue.04, pp.253-261, 2012.
DOI : 10.1371/journal.pone.0011896

L. E. Grzeskowiak, A. L. Gilbert, T. I. Sørensen, J. Olsen, H. T. Sørensen et al., Prenatal exposure to selective serotonin reuptake inhibitors and childhood overweight at 7 years of age, Annals of Epidemiology, vol.23, issue.11, pp.681-687, 2013.
DOI : 10.1016/j.annepidem.2013.08.005

R. C. Casper, B. E. Fleisher, J. C. Lee-ancajas, A. Gilles, E. Gaylor et al., Follow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy, The Journal of Pediatrics, vol.142, issue.4, pp.402-408, 2003.
DOI : 10.1067/mpd.2003.139

R. C. Casper, A. A. Gilles, B. E. Fleisher, J. Baran, G. Enns et al., Length of prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants: effects on neonatal adaptation and psychomotor development, Psychopharmacology, vol.113, issue.5697, pp.211-219, 2011.
DOI : 10.1542/peds.113.2.368

T. Heikkinen, U. Ekblad, P. Kero, S. Ekblad, and K. Laine, Citalopram in pregnancy and lactation, Clinical Pharmacology & Therapeutics, vol.72, issue.2, pp.184-191, 2002.
DOI : 10.1067/mcp.2002.126181

T. Heikkinen, U. Ekblad, P. Palo, and K. Laine, Pharmacokinetics of fluoxetine and norfluoxetine in pregnancy and lactation, Clinical Pharmacology & Therapeutics, vol.73, issue.4, pp.330-337, 2003.
DOI : 10.1016/S0009-9236(02)17634-X

V. Hendrick, L. M. Smith, S. Hwang, L. L. Altshuler, and D. Haynes, Weight Gain in Breastfed Infants of Mothers Taking Antidepressant Medications, The Journal of Clinical Psychiatry, vol.64, issue.4, pp.410-412, 2003.
DOI : 10.4088/JCP.v64n0409

M. E. Moretti, A. Sharma, B. Bar-oz, G. Koren, and S. Ito, Fluoxetine and its effects on the nursing infant: A prospective cohort study, Clinical Pharmacology & Therapeutics, vol.65, issue.2, p.141, 1999.
DOI : 10.1016/S0009-9236(99)80095-2

I. Nulman, G. Koren, J. Rovet, M. Barrera, A. Pulver et al., Neurodevelopment of Children Following Prenatal Exposure to Venlafaxine, Selective Serotonin Reuptake Inhibitors, or Untreated Maternal Depression, American Journal of Psychiatry, vol.169, issue.11, pp.169-1165, 2012.
DOI : 10.1176/appi.ajp.2012.11111721

I. Nulman, G. Koren, J. Rovet, M. Barrera, D. L. Streiner et al., , 2015.

, Neurodevelopment of children prenatally exposed to selective reuptake inhibitor antidepressants: Toronto sibling study, The Journal of Clinical Psychiatry, vol.76, issue.7, pp.842-849

I. Nulman, J. Rovet, D. E. Stewart, J. Wolpin, H. A. Gardner et al., Neurodevelopment of Children Exposed in Utero to Antidepressant Drugs, New England Journal of Medicine, vol.336, issue.4, pp.258-262, 1997.
DOI : 10.1056/NEJM199701233360404

K. L. Wisner, D. L. Bogen, D. Sit, M. Mcshea, C. Hughes et al., Does Fetal Exposure to SSRIs or Maternal Depression Impact Infant Growth?, American Journal of Psychiatry, vol.170, issue.5, 2013.
DOI : 10.1176/appi.ajp.2012.11121873

, American Journal of Psychiatry, vol.170, pp.485-493

K. A. Ertel, K. C. Koenen, J. W. Rich-edwards, and M. W. Gillman, Maternal Depressive Symptoms Not Associated with Reduced Height in Young Children in a US Prospective Cohort Study, PLoS ONE, vol.5, issue.10, p.13656, 2010.
DOI : 10.1371/journal.pone.0013656.t004

V. Grote, T. Vik, R. Von-kries, V. Luque, J. Socha et al., Maternal postnatal depression and child growth: a European cohort study, BMC Pediatrics, vol.27, issue.1, 2010.
DOI : 10.1038/sj.ijo.0802409

M. Ramsay, E. G. Gisel, J. Mccusker, F. Bellavance, and R. Platt, Infant sucking ability, non-organic failure to thrive, maternal characteristics, and feeding practices: A prospective cohort study, Developmental Medicine & Child Neurology, issue.06, pp.44-405, 2002.

I. S. Santos, A. Matijasevich, M. R. Domingues, and A. J. Barros, , 2010.

, Long-lasting maternal depression and child growth at 4 years of age: A cohort study, The Journal of pediatrics, vol.157, issue.3, pp.401-406

J. Li, J. Olsen, M. Vestergaard, C. Obel, J. L. Baker et al., Prenatal Stress Exposure Related to Maternal Bereavement and Risk of Childhood Overweight, PLoS ONE, vol.149, issue.7, p.11896, 2010.
DOI : 10.1371/journal.pone.0011896.s001

P. Sengupta, The laboratory rat: Relating its age with human's, International Journal of Preventive medicine, vol.4, issue.6, p.624, 2013.

J. D. Olivier, A. Valles, F. Van-heesch, A. Afrasiab-middelman, J. J. Roelofs et al., Fluoxetine administration to pregnant rats increases anxietyrelated behavior in the offspring, Psychopharmacology, issue.3, pp.217-419, 2011.

S. M. Gaukler, J. S. Ruff, T. Galland, K. A. Kandaris, T. K. Underwood et al.,

&. Potts and W. K. , Low-dose paroxetine exposure causes lifetime declines in male mouse body weight, reproduction and competitive ability as measured by the novel organismal performance assay, Neurotoxicology andTteratology, vol.47, pp.46-53, 2015.

P. A. Forcelli and S. C. Heinrichs, Teratogenic effects of maternal antidepressant exposure on neural substrates of drug-seeking behavior in offspring, Addiction Biology, vol.61, issue.1, pp.52-62, 2008.
DOI : 10.1016/S0168-0102(98)00097-2

W. F. Rayburn, C. L. Gonzalez, H. D. Christensen, T. C. Kupiec, J. A. Jacobsen et al., Effect of antenatal exposure to paroxetine (paxil) on growth and physical maturation of mice offspring, Journal of Maternal-Fetal Medicine, vol.9, issue.2, pp.136-141, 2000.
DOI : 10.1002/(sici)1520-6661(200003/04)9:2<136::aid-mfm10>3.0.co;2-q

T. S. Gouvêa, H. K. Morimoto, M. J. De-faria, E. G. Moreira, and D. C. Gerardin, Maternal exposure to the antidepressant fluoxetine impairs sexual motivation in adult male mice, Pharmacology Biochemistry and Behavior, vol.90, issue.3, pp.90-416, 2008.
DOI : 10.1016/j.pbb.2008.03.025

R. Vartazarmian, S. Malik, G. B. Baker, and P. Boksa, Long-term effects of fluoxetine or vehicle administration during pregnancy on behavioral outcomes in guinea pig offspring, Psychopharmacology, vol.296, issue.Suppl 7, pp.328-338, 2005.
DOI : 10.1176/ajp.153.11.1450

T. C. Deiró, J. Carvalho, E. D. Nascimento, J. M. Medeiros, F. Cajuhi et al., Neonatal exposure to citalopram, a serotonin selective reuptake inhibitor, programs a delay in the reflex ontogeny in rats, Arquivos de Neuro-Psiquiatria, vol.79, issue.Suppl, pp.66-736, 2008.
DOI : 10.1016/S0031-9384(03)00104-5

T. C. Deiró, R. Manhães-de-castro, J. E. Cabral-filho, J. M. Barreto-medeiros, S. L. Souza et al., Sertraline delays the somatic growth and reflex ontogeny in neonate rats, Physiology & Behavior, vol.87, issue.2, pp.338-344, 2006.
DOI : 10.1016/j.physbeh.2005.10.003

I. Rayen, D. L. Van-den-hove, J. Prickaerts, H. W. Steinbusch, and . Pawluski, J. L, 2011.

, Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence, PloS one, vol.6, issue.9, p.24003

N. N. Karpova, J. Lindholm, P. Pruunsild, T. Timmusk, and E. Castrén, Long-lasting behavioural and molecular alterations induced by early postnatal fluoxetine exposure are restored by chronic fluoxetine treatment in adult mice, European Neuropsychopharmacology, vol.19, issue.2, pp.97-108, 2009.
DOI : 10.1016/j.euroneuro.2008.09.002

G. J. Kummet, S. E. Haskell, G. M. Hermann, C. Ni, K. A. Volk et al., Neonatal SSRI Exposure Programs a Hypermetabolic State in Adult Mice, Journal of Nutrition and Metabolism, vol.44, issue.8, pp.1-8, 2012.
DOI : 10.1007/s00726-005-0280-z

M. Gemmel, N. Kokras, C. Dalla, and J. Pawluski, Perinatal fluoxetine prevents the effect of pre-gestational maternal stress on 5-HT in the PFC, but maternal stress has enduring effects on mPFC synaptic structure in offspring, Neuropharmacology, vol.128
DOI : 10.1016/j.neuropharm.2017.10.009

URL : https://hal.archives-ouvertes.fr/hal-01647158

A. R. Gobinath, J. L. Workman, C. Chow, S. E. Lieblich, and L. A. Galea, , 2016.

, Maternal postpartum corticosterone and fluoxetine differentially affect adult male and female offspring on anxiety-like behavior, stress reactivity, and hippocampal neurogenesis, Neuropharmacology, vol.101, pp.165-178

S. Bouali, A. Evrard, M. Chastanet, K. P. Lesch, M. Hamon et al., Sex hormone-dependent desensitization of 5-HT1A autoreceptors in knockout mice deficient in the 5-HT transporter, European Journal of Neuroscience, vol.16, issue.8, pp.18-2203, 2003.
DOI : 10.1016/0166-2236(85)90145-6

Q. Li, C. H. Wichems, L. Ma, L. D. Van-de-kar, F. Garcia et al., , 2003.

, Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice, Journal of Neurochemistry, vol.84, issue.6, pp.1256-1265

Q. Li, C. Wichems, A. Heils, K. P. Lesch, and D. L. Murphy, ) in 5-HT Transporter Knock-Out Mice: Gender and Brain Region Differences, The Journal of Neuroscience, vol.20, issue.21, pp.20-7888, 2000.
DOI : 10.1523/JNEUROSCI.20-21-07888.2000

S. J. Line, C. Barkus, C. Coyle, K. A. Jennings, R. M. Deacon et al., Opposing alterations in anxiety and species-typical behaviours in serotonin transporter overexpressor and knockout mice, European Neuropsychopharmacology, vol.21, issue.1, pp.108-116, 2011.
DOI : 10.1016/j.euroneuro.2010.08.005

N. Üçeyler, M. Schütt, F. Palm, C. Vogel, M. Meier et al.,

, Lack of the serotonin transporter in mice reduces locomotor activity and leads to genderdependent late onset obesity, International Journal of Obesity, vol.34, issue.4, pp.701-711

J. R. Homberg, S. E. Fleur, and E. Cuppen, Serotonin Transporter Deficiency Increases Abdominal Fat in Female, but Not Male Rats, Obesity, vol.55, issue.1, pp.137-145, 2010.
DOI : 10.1016/j.neuropharm.2008.04.016

B. Leuner, P. J. Fredericks, C. Nealer, and C. Albin-brooks, Chronic Gestational Stress Leads to Depressive-Like Behavior and Compromises Medial Prefrontal Cortex Structure and Function during the Postpartum Period, PLoS ONE, vol.3, issue.2, p.89912, 2014.
DOI : 10.1371/journal.pone.0089912.t001

J. W. Smith, J. R. Seckl, A. T. Evans, B. Costall, and J. W. Smythe, Gestational stress induces post-partum depression-like behaviour and alters maternal care in rats, Psychoneuroendocrinology, vol.29, issue.2, pp.29-227, 2004.
DOI : 10.1016/S0306-4530(03)00025-8

S. Brummelte and L. A. Galea, Chronic corticosterone during pregnancy and postpartum affects maternal care, cell proliferation and depressive-like behavior in the dam, Hormones and Behavior, vol.58, issue.5, pp.769-779, 2010.
DOI : 10.1016/j.yhbeh.2010.07.012

S. Brummelte, J. L. Pawluski, and L. A. Galea, High post-partum levels of corticosterone given to dams influence postnatal hippocampal cell proliferation and behavior of offspring: A model of post-partum stress and possible depression, Hormones and Behavior, vol.50, issue.3, pp.370-382, 2006.
DOI : 10.1016/j.yhbeh.2006.04.008

S. Maccari, M. Darnaudery, S. Morley-fletcher, A. R. Zuena, C. Cinque et al., Prenatal stress and long-term consequences: implications of glucocorticoid hormones, Neuroscience & Biobehavioral Reviews, vol.27, issue.1-2, pp.119-127, 2003.
DOI : 10.1016/S0149-7634(03)00014-9

I. Rayen, H. W. Steinbusch, T. D. Charlier, and J. L. Pawluski, Developmental fluoxetine exposure facilitates sexual behavior in female offspring, Psychopharmacology, vol.7, issue.1, pp.123-133, 2014.
DOI : 10.1016/0091-3057(86)90167-X

URL : https://hal.archives-ouvertes.fr/hal-01122028

I. Lucki, The spectrum of behaviors influenced by serotonin, Biological Psychiatry, vol.44, issue.3, pp.151-162, 1998.
DOI : 10.1016/S0006-3223(98)00139-5

K. R. Bruce, H. Steiger, S. N. Young, N. M. Kin, M. Israel et al., Impact of acute tryptophan depletion on mood and eating-related urges in bulimic and nonbulimic women, Journal of Psychiatry Neuroscience, vol.34, issue.5, pp.376-382, 2009.

T. D. Brewerton, Toward a unified theory of serotonin dysregulation in eating and related disorders, Psychoneuroendocrinology, vol.20, issue.6, pp.561-590, 1995.
DOI : 10.1016/0306-4530(95)00001-5

K. J. Simansky, Serotonergic control of the organization of feeding and satiety, Behavioural Brain Research, vol.73, issue.1-2, pp.37-42, 1996.
DOI : 10.1016/0166-4328(96)00066-6

S. M. Hoy, Lorcaserin: A Review of its Use in Chronic Weight Management, Drugs, vol.83, issue.6, pp.463-473, 2013.
DOI : 10.1016/S0002-9149(98)01064-9

A. M. Cypess, S. Lehman, G. Williams, I. Tal, D. Rodman et al., Identification and importance of brown adipose tissue in adult humans, 2009.

, New England Journal of Medicine, vol.360, issue.15, pp.1509-1517

J. D. Crane, R. Palanivel, E. P. Mottillo, A. L. Bujak, H. Wang et al.,

J. , Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis, Nature Medicine, vol.21, issue.2, pp.166-172, 2015.

B. L. Jacobs and C. A. Fornal, Serotonin and motor activity, Current Opinion in Neurobiology, vol.7, issue.6, pp.820-825, 1997.
DOI : 10.1016/S0959-4388(97)80141-9

E. L. Moses-kolko, D. Bogen, J. Perel, A. Bregar, K. Uhl et al., Neonatal Signs After Late In Utero Exposure to Serotonin Reuptake Inhibitors, JAMA, vol.293, issue.19, pp.293-2372, 2005.
DOI : 10.1001/jama.293.19.2372

A. L. Salisbury, K. L. Wisner, T. Pearlstein, C. L. Battle, L. Stroud et al., Newborn neurobehavioral patterns are differentially related to prenatal maternal major depressive disorder and serotonin reuptake inhibitor treatment, Depression and Anxiety, vol.49, issue.11, pp.28-1008, 2011.
DOI : 10.1111/j.1469-7610.2008.01914.x

A. K. Santucci, L. T. Singer, S. R. Wisniewski, J. F. Luther, H. F. Eng et al., Impact of Prenatal Exposure to Serotonin Reuptake Inhibitors or Maternal Major Depressive Disorder on Infant Developmental Outcomes, The Journal of Clinical Psychiatry, issue.10, pp.75-1088, 2014.
DOI : 10.4088/JCP.13m08902

M. V. Smith, A. Sung, B. Shah, L. Mayes, D. S. Klein et al., , 2013.

, Neurobehavioral assessment of infants born at term and in utero exposure to serotonin reuptake inhibitors, Early Human Development, vol.89, issue.2, pp.81-86

P. S. Zeskind and L. E. Stephens, Maternal Selective Serotonin Reuptake Inhibitor Use During Pregnancy and Newborn Neurobehavior, PEDIATRICS, vol.113, issue.2, pp.368-375, 2004.
DOI : 10.1542/peds.113.2.368

H. E. Nasreen, Z. N. Kabir, Y. Forsell, and M. Edhborg, Impact of maternal depressive symptoms and infant temperament on early infant growth and motor development: Results from a population based study in Bangladesh, Journal of Affective Disorders, vol.146, issue.2, pp.254-261, 2013.
DOI : 10.1016/j.jad.2012.09.013

L. H. Pedersen, T. B. Henriksen, and J. Olsen, Fetal Exposure to Antidepressants and Normal Milestone Development at 6 and 19 Months of Age, PEDIATRICS, vol.125, issue.3, pp.600-6008, 2010.
DOI : 10.1542/peds.2008-3655

J. T. Mortensen, J. Olsen, H. Larsen, J. Bendsen, C. Obel et al., , 2003.

, Psychomotor development in children exposed in utero to benzodiazepines, antidepressants, neuroleptics, and anti-epileptics, European Journal of Epidemiology, vol.18, issue.8, pp.769-771

M. Galbally, A. J. Lewis, and A. Buist, Child developmental outcomes in preschool children following antidepressant exposure in pregnancy, Australian & New Zealand Journal of Psychiatry, vol.59, issue.7, pp.49-642, 2015.
DOI : 10.1073/pnas.1121263109

M. Galbally, A. J. Lewis, and A. Buist, Developmental Outcomes of Children Exposed to Antidepressants in Pregnancy, Australian & New Zealand Journal of Psychiatry, vol.14, issue.544, pp.393-399, 2011.
DOI : 10.1056/NEJMra0708473

M. Handal, S. Skurtveit, K. Furu, S. Hernandez-diaz, E. Skovlund et al., Motor development in children prenatally exposed to selective serotonin reuptake inhibitors: a large population-based pregnancy cohort study, BJOG: An International Journal of Obstetrics & Gynaecology, vol.19, issue.12, pp.123-1908, 2015.
DOI : 10.1016/j.reprotox.2004.07.004

A. C. Tse, J. W. Rich-edwards, S. L. Rifas-shiman, M. W. Gillman, and E. Oken, , 2010.

, Association of maternal prenatal depressive symptoms with child cognition at age 3 years. Paediatric and Perinatal Epidemiology, pp.232-240

M. C. Partridge, A. L. Salisbury, and L. L. Lagasse, Fine Motor Differences and Prenatal Serotonin Reuptake Inhibitors Exposure, The Journal of Pediatrics, vol.175, pp.144-149, 2016.
DOI : 10.1016/j.jpeds.2016.04.065

B. H. Wrotniak, L. H. Epstein, J. M. Dorn, K. E. Jones, and V. A. Kondilis, The Relationship Between Motor Proficiency and Physical Activity in Children, PEDIATRICS, vol.118, issue.6, pp.118-1758, 2006.
DOI : 10.1542/peds.2006-0742

T. C. Deiró, J. Carvalho, E. D. Nascimento, J. M. Medeiros, F. Cajuhi et al., Neonatal exposure to citalopram, a serotonin selective reuptake inhibitor, programs a delay in the reflex ontogeny in rats, Arquivos de Neuro-Psiquiatria, vol.79, issue.Suppl, pp.66-736, 2008.
DOI : 10.1016/S0031-9384(03)00104-5

N. Y. Glazova, S. A. Merchieva, M. A. Volodina, E. A. Sebentsova, D. M. Manchenko et al., Effects of neonatal fluvoxamine administration on the physical development and activity of the serotoninergic system in white rats, Acta Naturae, vol.6, issue.22, pp.98-105, 2014.

B. Zimmerberg and S. C. Germeyan, Effects of neonatal fluoxetine exposure on behavior across development in rats selectively bred for an infantile affective trait, Developmental Psychobiology, vol.47, issue.9, pp.141-152, 2015.
DOI : 10.1016/j.bbr.2004.11.009

L. J. Lee, Neonatal Fluoxetine Exposure Affects the Neuronal Structure in the Somatosensory Cortex and Somatosensory-Related Behaviors in Adolescent Rats, Neurotoxicity Research, vol.425, issue.4, pp.212-223, 2009.
DOI : 10.1016/S0140-6736(05)17865-9

L. J. Kepser and J. R. Homberg, The neurodevelopmental effects of serotonin: A behavioural perspective, Behavioural Brain Research, vol.277, pp.3-13, 2015.
DOI : 10.1016/j.bbr.2014.05.022

A. Bonnin and P. Levitt, Fetal, maternal, and placental sources of serotonin and new implications for developmental programming of the brain, Neuroscience, vol.197, pp.1-7, 2011.
DOI : 10.1016/j.neuroscience.2011.10.005

S. Migliarini, G. Pacini, B. Pelosi, G. Lunardi, and M. Pasqualetti, Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation, Molecular Psychiatry, vol.6, issue.10, pp.18-1106, 2013.
DOI : 10.1002/hipo.20759

N. R. Saunders, S. A. Liddelow, and K. M. Dziegielewska, Barrier Mechanisms in the Developing Brain, Frontiers in Pharmacology, vol.3, pp.1-18, 2012.
DOI : 10.3389/fphar.2012.00046

E. A. Mayer, Gut feelings: the emerging biology of gut???brain communication, Nature Reviews Neuroscience, vol.351, issue.8, pp.453-466, 2011.
DOI : 10.1098/rstb.1996.0125

URL : http://europepmc.org/articles/pmc3845678?pdf=render

G. M. Mawe and J. M. Hoffman, Serotonin signalling in the gut???functions, dysfunctions and therapeutic targets, Nature Reviews Gastroenterology & Hepatology, vol.20, issue.8, pp.473-486, 2013.
DOI : 10.1053/j.gastro.2005.08.005

URL : http://europepmc.org/articles/pmc4048923?pdf=render

S. H. Rhee, C. Pothoulakis, and E. A. Mayer, Principles and clinical implications of the brain???gut???enteric microbiota axis, Nature Reviews Gastroenterology & Hepatology, vol.122, issue.5, pp.306-314, 2009.
DOI : 10.1016/S0079-6123(08)62136-6

C. M. Nijenhuis, P. G. Ter-horst, L. De-jong-van-den-berg, and B. Wilffert, , 2012.

, Disturbed development of the enteric nervous system after in utero exposure of selective serotonin re-uptake inhibitors and tricyclic antidepressants. Part 1: Literature review, British Journal of Clinical Pharmacology, vol.73, issue.1, pp.16-26

C. M. Nijenhuis, P. G. Ter-horst, N. Van-rein, B. Wilffert, and L. De-jong-van-den-berg, Disturbed development of the enteric nervous system after in utero exposure of selective serotonin re-uptake inhibitors and tricyclic antidepressants. Part 2: Testing the hypotheses, British Journal of Clinical Pharmacology, vol.122, issue.1, pp.126-134, 2012.
DOI : 10.1152/ajpgi.90712.2008

T. G. Dinan and J. F. Cryan, The Microbiome-Gut-Brain Axis in Health and Disease, Gastroenterology Clinics of North America, vol.46, issue.1, pp.77-89, 2017.
DOI : 10.1016/j.gtc.2016.09.007

O. 'mahony, S. M. Clarke, G. Dinan, T. G. Cryan, and J. F. , Early-life adversity and brain development: Is the microbiome a missing piece of the puzzle, Neuroscience, vol.342, pp.37-54, 2017.

T. G. Dinan and J. F. Cryan, Brain-Gut-Microbiota Axis and Mental Health, Psychosomatic Medicine, vol.79, issue.8, pp.79-920, 2017.
DOI : 10.1097/PSY.0000000000000519

G. Clarke, S. Grenham, P. Scully, P. Fitzgerald, R. D. Moloney et al., The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner, Molecular Psychiatry, vol.10, issue.6, pp.666-674, 2013.
DOI : 10.1111/j.1651-2227.2008.01060.x

S. Himpel, J. Bartels, K. Zimdars, G. Huether, L. Adler et al., Association between body weight of newborn rats and density of serotonin transporters in the frontal cortex at adulthood, Journal of Neural Transmission, vol.33, issue.Suppl 3, pp.295-302, 2006.
DOI : 10.1097/00004703-200304000-00009

P. J. Turnbaugh and J. I. Gordon, The core gut microbiome, energy balance and obesity, The Journal of Physiology, vol.106, issue.17, pp.4153-4158, 2009.
DOI : 10.1073/pnas.0812600106

K. J. Davey, S. M. O-'mahony, H. Schellekens, O. O-'sullivan, J. Bienenstock et al., Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters, Psychopharmacology, vol.128, issue.Suppl 1, pp.155-169, 2012.
DOI : 10.1016/j.jss.2005.04.017

K. J. Davey, S. M. O-'mahony, H. Schellekens, O. O-'sullivan, J. Bienenstock et al., Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters, Psychopharmacology, vol.128, issue.Suppl 1, pp.155-169, 2012.
DOI : 10.1016/j.jss.2005.04.017

M. Hamilton, A RATING SCALE FOR DEPRESSION, Journal of Neurology, Neurosurgery & Psychiatry, vol.23, issue.1, pp.56-62, 1960.
DOI : 10.1136/jnnp.23.1.56

J. L. Cox, J. M. Holden, and R. Sagovsky, Detection of Postnatal Depression, British Journal of Psychiatry, vol.150, issue.06, pp.782-786, 1987.
DOI : 10.1192/bjp.150.6.782

L. C. Abbott and U. H. Winzer-serhan, Smoking during pregnancy: lessons learned from epidemiological studies and experimental studies using animal models, Critical Reviews in Toxicology, vol.15, issue.3, pp.279-303, 2012.
DOI : 10.1002/bdrb.20052

L. Bonari, N. Pinto, E. Ahn, and A. Einarson, Perinatal Risks of Untreated Depression during Pregnancy, The Canadian Journal of Psychiatry, vol.59, issue.7, pp.49-726, 2004.
DOI : 10.1001/archpsyc.60.3.253

T. Kurki, V. Hiilesmaa, R. Raitasalo, H. Mattila, and O. Ylikorkala, Depression and anxiety in early pregnancy and risk for preeclampsia, Obstetrics & Gynecology, vol.95, issue.4, pp.487-490, 2000.
DOI : 10.1016/s0029-7844(99)00602-x

M. R. Munafò, J. Heron, and R. Araya, Smoking patterns during pregnancy and postnatal period and depressive symptoms, Nicotine & Tobacco Research, vol.10, issue.11, pp.1609-1602, 2008.
DOI : 10.1080/14622200802412895