 |
 |
 |
Journal articles
Preliminary Structure-Activity Relationship (SAR) of a Novel Series of Pyrazole SKF-96365 Analogues as Potential Store-Operated Calcium Entry (SOCE) Inhibitors
Abstract : From a series of (1, 1)-1[β-(phenylalkoxy)-(phenetyl)]-1-pyrazolium hydrochloride as new analogues of SKF-96365, one has an interesting effect for endoplasmic reticulum (ER) Carelease and store-operated Caentry (SOCE) (IC25 μM) on the PLP-B lymphocyte cell line. A successful resolution of (±) 1-phenyl-2-(1-pyrazol-1-yl)ethan-1-ol has been developed by using the method of "half-concentration" in the presence of (+)-(1)- or (-)-(1)-CSA.
Cited literature [72 references]
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01744289
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, July 16, 2019 - 4:20:50 PM
Last modification on : Tuesday, February 23, 2021 - 3:20:51 PM
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, July 16, 2019 - 4:20:50 PM
Last modification on : Tuesday, February 23, 2021 - 3:20:51 PM
File
ijms-19-00856.pdf
Publisher files allowed on an open archive