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A comprehensive approach of the gender bias in occupational cancer epidemiology A systematic review of lung cancer studies (2003-2014)

Abstract : Background - In occupational epidemiology, a male-centered perspective often predominates. We aimed to describe current research practices in terms of gender consideration at different stages of epidemiological studies. Methods - A systematic review of occupational lung cancer publications indexed in PubMed was conducted over the period 2003-2014. Articles were described according to the sex composition of their study sample. Results - In 243 studies, 7 (3%) were women-only, 101 (41%) were mixed, with a disproportionate men-to-women ratio (P50 = 3.5; P75 = 12.4). A shift was observed from mixed and unspecified source populations to men-only final samples. Our results also suggest implicit generalization of results from men-only studies, a lack of tests of interaction and often unjustified sex-adjustment for mixed studies. Conclusions - The lower proportion of women in studies cannot be fully explained by their under-representation in the target populations, since there were large numbers of women among both potentially exposed workers and patients diagnosed with lung cancer.
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01780219
Contributor : Xavier Chard-Hutchinson <>
Submitted on : Friday, April 27, 2018 - 12:02:37 PM
Last modification on : Saturday, September 19, 2020 - 3:52:22 AM

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Charles-Olivier Betansedi, Patricia Vaca Vasquez, Emilie Counil. A comprehensive approach of the gender bias in occupational cancer epidemiology A systematic review of lung cancer studies (2003-2014). American Journal of Industrial Medicine, Wiley, 2018, 61 (5), pp.372-382. ⟨10.1002/ajim.22823⟩. ⟨hal-01780219⟩

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