Bruno-3 regulates sarcomere components expression and contributes to muscle phenotypes of Myotonic dystrophy type 1

Lucie Picchio (1) , Vincent Legagneux (2, 3) , Stéphane Deschamps (2) , Yoan Renaud (1) , Sabine Chauveau (1) , Luc Paillard (2) , Krzysztof Jagla (1)

1 GReD - Génétique, Reproduction et Développement
2 IGDR - Institut de Génétique et Développement de Rennes
3 Irset - Institut de recherche en santé, environnement et travail

Keywords: RNA CLIP; myotonic dystrophy type 1; Bruno-3; Drosophila; Celf1; Steinert disease; mRNA stability; DM1; CLIP-RNA

Domains: Life Sciences [q-bio]; Ecology, environment; Health

Lucie Picchio, Vincent Legagneux, Stéphane Deschamps, Yoan Renaud, Sabine Chauveau, et al.. Bruno-3 regulates sarcomere components expression and contributes to muscle phenotypes of Myotonic dystrophy type 1. Disease Models & Mechanisms, 2018, 11 (5), pp.dmm031849. ⟨10.1242/dmm.031849⟩. ⟨hal-01795809⟩