H. G. Abadin, C. H. Chou, and F. T. Llados, Health effects classification and its role 538 in the derivation of minimal risk levels: immunological effects, Regul. Toxicol. 539 Pharm, vol.47, issue.3, pp.249-256, 2007.

, Afssa-Agence française de sécurité sanitaire des aliments, 2003.

, éventuelle d'une corrélation significative entre les teneurs des différents 542 congénères de PCB

A. M. Api, Toxicological profile of diethyl phthalate: a vehicle for fragrance and 544 cosmetic ingredients, Food and Chemical Toxicology, vol.39, issue.2, pp.97-108, 2001.

, Toxicological profile 546 for Polycyclic Aromatic Hydrocarbons (PAHs), ATSDR-Agency for Toxic Substances and Disease Registry, 1995.

, Toxicological profile 549 for Polychlorinated Biphenyls (PCBs), ATSDR-Agency for Toxic Substances and Disease Registry, 2000.

, Toxicological profile 552 for Di(2-ethylhexyl)phthalate (DEHP), ATSDR-Agency for Toxic Substances and Disease Registry, 2002.

, Toxicological profile 555 for Hexachlorocyclohexane, ATSDR-Agency for Toxic Substances and Disease Registry, 2005.

K. Fournier, P. Glorennec, and N. Bonvallot, An exposure-based framework for 601 grouping pollutants for a cumulative risk assessment approach: Case study of indoor 602 semi-volatile organic compounds, Environ. Res, vol.130, pp.20-28, 2014.

K. Fournier, C. Tebby, F. Zeman, P. Glorennec, D. Zmirou-navier et al., Multiple exposures to indoor contaminants: Derivation of benchmark doses 605 and relative potency factors based on male reprotoxic effects, Regul. Toxicol. Pharm, vol.606, pp.23-30, 2016.

K. Fournier, E. Baumont, P. Glorennec, and N. Bonvallot, Relative toxicity for indoor 608 semi volatile organic compounds based on neuronal death, Toxicol. Lett, vol.279, pp.33-42, 2017.
DOI : 10.1016/j.toxlet.2017.07.875
URL : https://hal-univ-rennes1.archives-ouvertes.fr/hal-01579605/file/Fournier%20et%20al.%20-%20Relative%20toxicity%20for%20indoor%20semi%20volatile%20organic.pdf

S. Fujii, K. Yabe, M. Furukawa, M. Hirata, M. Kiguchi et al., A two610 generation reproductive toxicity study of diethyl phthalate (DEP) in rats. The Journal 611 of toxicological sciences, vol.30, pp.97-116, 2005.

P. Glorennec, F. Mercier, O. Blanchard, N. Bonvallot, O. Ramalho et al., Cumulative indoor exposures to Semi-Volatile Organic Compounds (SVOCs) 614 in France: the ECOS project, vol.613, 2011.

, Proceedings of meeting held 5-10, p.9781627482721, 2011.

L. E. Gray, J. Ostby, J. Furr, M. Price, D. R. Veeramachaneni et al., , 2000.

, Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP

, DOTP, alters sexual differentiation of the male rat, Toxicological Sciences, vol.58, issue.2, pp.350-621

L. E. Gray, V. S. Wilson, T. Stoker, C. Lambright, J. Furr et al., Adverse effects of environmental antiandrogens and androgens on 624 reproductive development in mammals, Int. J. Androl, vol.29, issue.623, pp.96-104, 2006.

N. Guida, G. Laudati, M. Galgani, M. Santopaolo, P. Montuori et al., , p.626

G. Canzoniero, L. Formisano, and L. , Histone deacetylase 4 promotes ubiquitin627 dependent proteasomal degradation of Sp3 in SH-SY5Y cells treated with di (2628 ethylhexyl) phthalate (DEHP), determining neuronal death. Toxicology and applied 629 pharmacology, vol.280, pp.190-198, 2014.

R. Habert, V. Muczynski, A. Lehraiki, R. Lambrot, C. Lécureuil et al., , p.631

V. Rouiller-fabre, Adverse effects of endocrine disruptors on the foetal testis 632 development: focus on the phthalates, Folia Histochem. Cyto, vol.47, issue.5, pp.67-74, 2009.

B. R. Hannas, C. S. Lambright, J. Furr, K. L. Howdeshell, V. S. Wilson et al., Dose-response assessment of fetal testosterone production and gene 635 expression levels in rat testes following in utero exposure to diethylhexyl phthalate, 636 diisobutyl phthalate, diisoheptyl phthalate, and diisononyl phthalate, Toxicol. Sci, vol.637, issue.1, pp.206-216, 2011.

R. Hauser, J. D. Meeker, N. P. Singh, M. J. Silva, L. Ryan et al., DNA damage in human sperm is related to urinary levels of phthalate 640 monoester and oxidative metabolites, Human reproduction, vol.22, issue.3, pp.688-695, 2006.

, Some 642 non-heterocyclic polycyclic aromatic hydrocarbons and some related exposures, IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, vol.92, p.1, 2010.

. Ineris, Évaluation de la relation 645 dose-réponse pour des effets cancérigènes : Approche substance par substance 646 (facteurs d'équivalence toxique-FET) et approche par mélanges. Évaluation de la 647 relation dose-réponse. Institut National de l'Environnement et des Risques. Verneuil 648 en Halatte, Hydrocarbures aromatiques polycycliques (HAPs), 2003.

. Inserm, Expertise collective : Pesticides-Effets sur la santé, pp.978-980, 2013.

V. R. Kay, M. S. Bloom, and W. G. Foster, Reproductive and developmental effects of 653 phthalate diesters in males, Crit. Rev. Toxicol, vol.44, issue.6, pp.467-498, 2014.

R. W. Kobrosly, S. Evans, A. Miodovnik, E. S. Barrett, S. W. Thurston et al., , p.655

S. H. Swan, Prenatal phthalate exposures and neurobehavioral development 656 scores in boys and girls at 6-10 years of age. Environmental health perspectives, vol.657, p.521, 2014.

M. Levin, B. Morsey, C. Mori, P. R. Nambiar, and S. De-guise, Non-coplanar PCB659 mediated modulation of human leukocyte phagocytosis: a new mechanism for 660 immunotoxicity, Journal of Toxicology and Environmental Health, Part A, vol.68, issue.22, pp.661-1977, 2005.

C. H. Lin, T. J. Chen, S. S. Chen, P. C. Hsiao, and R. C. Yang, Activation of Trim17 663 by PPAR? is involved in Di (2-ethylhexyl) phthalate (DEHP)-induced apoptosis on 664 Neuro-2a cells, Toxicology letters, vol.206, issue.3, pp.245-251, 2011.

G. Lottrup, A. M. Andersson, H. Leffers, G. K. Mortensen, J. Toppari et al., , p.666

K. M. Main, Possible impact of phthalates on infant reproductive health, International journal of andrology, vol.667, issue.1, pp.172-180, 2006.

C. Mandin, F. Mercier, J. Lucas, O. Ramalho, O. Blanchard et al., ECOS-POUSS: A Nationwide Survey of Semi, 2014.

, Volatile Organic Compounds in Home Settled Dust, Proceedings of the Indoor Air, vol.671, pp.143-148, 2014.

C. Mandin, F. Mercier, O. Ramalho, J. P. Lucas, E. Gilles et al., , p.673

P. Glorennec, L. Bot, and B. , Semi-volatile organic compounds in the 674 particulate phase in dwellings: A nationwide survey in France, Atmos. Environ, vol.136, pp.675-82, 2016.

M. Matsumoto, M. Hirata-koizumi, and M. Ema, Potential adverse effects of phthalic 677 acid esters on human health: a review of recent studies on reproduction. Regulatory 678, Toxicology and Pharmacology, vol.50, issue.1, pp.37-49, 2008.

M. E. Meek, A. R. Boobis, K. M. Crofton, G. Heinemeyer, M. Van-raaij et al., Risk assessment of combined exposure to multiple chemicals: a WHO/IPCS 681 framework, Regul. Toxicol. Pharm, vol.60, issue.2, pp.1-14, 2011.

F. Mercier, P. Glorennec, O. Thomas, L. Bot, and B. , Organic contamination of settled 683 house dust: a review for exposure assessment purposes, Environ. Sci. Technol, vol.45, pp.684-6716, 2011.

F. Mercier, P. Glorennec, O. Blanchard, L. Bot, and B. , Analysis of semi-volatile organic 686 compounds in indoor suspended particulate matter by thermal desorption coupled with 687 gas chromatography / mass spectrometry, Journal of Chromatography A, vol.1254, pp.107-121, 2012.

F. Mercier, E. Gilles, G. Saramito, P. Glorennec, L. Bot et al., A multi-residue 689 method for the simultaneous analysis in indoor dust of several classes of semi-volatile 690 organic compounds by pressurized liquid extraction and gas chromatography/tandem 691 mass spectrometry, J. Chromatogr. A, vol.1336, pp.101-111, 2014.

A. Miodovnik, A. Edwards, D. C. Bellinger, and R. Hauser, Developmental 693 neurotoxicity of ortho-phthalate diesters: review of human and experimental evidence, 2014.

, Neurotoxicology, vol.41, pp.112-122

, Diethyl phthalate: reproduction and fertility assessment in CD-1 mice when 696 administered in the feed, NTP, p.697, 1984.

, National Institutes of Health, National Toxicology Program, 1984.

M. Pelletier, N. Bonvallot, O. Ramalho, C. Mandin, W. Wei et al., , p.700

O. Blanchard, L. Bot, B. Glorennec, and P. , Indoor residential exposure to 701 semivolatile organic compounds in France, Environ. Int, 2017.

M. Pelletier, N. Bonvallot, and P. Glorennec, Aggregating exposures & cumulating 703 risk for semivolatile organic compounds: A review, Environ. Res, vol.158, pp.649-659, 2017.

C. Pereira, K. Mapuskar, and C. V. Rao, Effect of diethyl phthalate on rat testicular 705 antioxidant system: A dose-dependent toxicity study. Pesticide biochemistry and 706 physiology, vol.90, pp.52-57, 2008.
DOI : 10.1016/j.pestbp.2007.07.008

I. Rostami and A. L. Juhasz, Assessment of persistent organic pollutant (POP) 708 bioavailability and bioaccessibility for human health exposure assessment: a critical 709 review, Crit. Rev. Env. Sci. Tec, vol.41, issue.7, pp.623-656, 2011.
DOI : 10.1080/10643380903044178

D. A. Sarigiannis and U. Hansen, Considering the cumulative risk of mixtures of 711 chemicals-a challenge for policy makers, Environ. Health, vol.11, issue.1, p.18, 2012.

S. G. Selevan, C. A. Kimmel, and P. Mendola, Identifying critical windows of 713 exposure for children's health, Environ. Health Persp, vol.108, p.451, 2000.

S. H. Swan, K. M. Main, F. Liu, S. L. Stewart, R. L. Kruse et al.,

L. , Decrease in anogenital distance among male infants with prenatal phthalate 716 exposure, Environ. Health Persp, pp.1056-1061, 2005.

H. Tryphonas, Immunotoxicity of polychlorinated biphenyls: present status and future 718 considerations, Dioxins and the Immune System, pp.149-162, 1994.

H. Tryphonas, Immunotoxicity of PCBs (aroclors) in relation to Great Lakes, 1995.

, Health Persp, vol.103, p.35

U. S. Epa, PCBs: Cancer Dose-Response Assessment and Application to, 1996.

, Office of Research 723 and Development, vol.724, 1996.

U. S. Epa, A Review of the Reference Dose and Reference Concentration Processes, 2002.

, Risk Assessment Forum

U. S. Epa, Guidelines for carcinogen risk assessment, p.729, 2005.

. Agency, Risk Assessment Forum

. , IRIS Glossary, 2008.

M. Van-den-berg, L. Birnbaum, A. T. Bosveld, B. Brunström, P. Cook et al., , p.734

T. Kubiak, Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for 735 humans and wildlife, Environ. Health Persp, vol.106, issue.12, p.775, 1998.

M. Van-den-berg, L. S. Birnbaum, M. Denison, M. De-vito, W. Farland et al., , p.737

M. Rose, The 2005 World Health Organization reevaluation of human and 738 mammalian toxic equivalency factors for dioxins and dioxin-like compounds, 2006.

. Sci, , vol.93, pp.223-241

C. J. Weschler and W. W. Nazaroff, Semivolatile organic compounds in indoor 741 environments, Atmos. Environ, vol.42, issue.40, pp.9018-9040, 2008.

C. J. Weschler and W. W. Nazaroff, SVOC partitioning between the gas phase and 743 settled dust indoors, Atmos. Environ, vol.44, issue.30, pp.3609-3620, 2010.
DOI : 10.1016/j.atmosenv.2010.06.029

, Guidelines for drinking-water quality, incorporating 1st and 2nd addenda, vol.1, 2008.

K. Yolton, Y. Xu, D. Strauss, M. Altaye, A. M. Calafat et al., Prenatal 747 exposure to bisphenol A and phthalates and infant neurobehavior, Neurotoxicology 748 and teratology, vol.33, issue.5, pp.558-566, 2011.