One-Pot Synthesis of Dihydropyrimidinones/Thiones Catalyzed by White Marble a Metamorphic Rock an Efficient and Reusable Catalyst for the Biginelli Reaction

K. El Mejdoubi; B. Sallek; H. Cherkaoui; H. Chaair; H. Oudadesse

One-Pot Synthesis of Dihydropyrimidinones/Thiones Catalyzed by White Marble a Metamorphic Rock an Efficient and Reusable Catalyst for the Biginelli Reaction

K. El Mejdoubi ¹ B. Sallek ¹ H. Cherkaoui ¹ H. Chaair ² H. Oudadesse ³

2 FSTM - Faculté des Sciences et Techniques [Mohammedia]

3 ISCR - Institut des Sciences Chimiques de Rennes

Abstract : In this work, we report a simple, efficient and green protocol for the synthesis of dihydropyrimidinones/thiones (products of Biginelli reaction) by the use of white marble as an effective heterogeneous catalyst. Short reaction times, high product yields, simple processing procedure and reusability of the catalyst are the superior characteristics of this protocol.

Keywords : green catalyst white marble Biginelli reaction 4-dihydropyrimidin-2(1H)-ones/thiones

Document type :

Journal articles

Domain :

Chemical Sciences / Catalysis

Chemical Sciences / Organic chemistry

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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01833234
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Submitted on : Monday, September 10, 2018 - 3:40:48 PM
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One-Pot Synthesis of Dihydropyrimidinones/Thiones Catalyzed by White Marble a Metamorphic Rock an Efficient and Reusable Catalyst for the Biginelli Reaction

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One-Pot Synthesis of Dihydropyrimidinones/Thiones Catalyzed by White Marble a Metamorphic Rock an Efficient and Reusable Catalyst for the Biginelli Reaction

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