One-Pot Synthesis of Dihydropyrimidinones/Thiones Catalyzed by White Marble a Metamorphic Rock an Efficient and Reusable Catalyst for the Biginelli Reaction

K. El Mejdoubi 1 B. Sallek 1 H. Cherkaoui 1 H. Chaair 2 H. Oudadesse 3
1 UIT - Université Ibn Tofaïl
2 FSTM - Faculte des sciences et Techniques Mohammedia [Casablanca]
3 ISCR - Institut des Sciences Chimiques de Rennes
Abstract : In this work, we report a simple, efficient and green protocol for the synthesis of dihydropyrimidinones/thiones (products of Biginelli reaction) by the use of white marble as an effective heterogeneous catalyst. Short reaction times, high product yields, simple processing procedure and reusability of the catalyst are the superior characteristics of this protocol.
Keywords : green catalyst white marble Biginelli reaction 4-dihydropyrimidin-2(1H)-ones/thiones
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K. El Mejdoubi, B. Sallek, H. Cherkaoui, H. Chaair, H. Oudadesse. One-Pot Synthesis of Dihydropyrimidinones/Thiones Catalyzed by White Marble a Metamorphic Rock an Efficient and Reusable Catalyst for the Biginelli Reaction. Kinetics and Catalysis, MAIK Nauka/Interperiodica, 2018, 59 (3), pp.290-295. ⟨10.1134/S0023158418030126⟩. ⟨hal-01833234⟩

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