S. Bardak-ozcem and O. R. Sipahi, An updated approach to healthcare-associated meningitis, Expert Review of Anti-infective Therapy, vol.310, issue.3
DOI : 10.1001/jama.2013.280506

, Infect. Ther, vol.12, pp.333-375, 2014.

D. Van-de-beek, J. M. Drake, and A. R. , Nosocomial Bacterial Meningitis, New England Journal of Medicine, vol.362, issue.2, pp.146-54, 2010.
DOI : 10.1056/NEJMra0804573

O. R. Sipahi, A. Nazli-zeka, M. Ta?bakan, H. Pullukçu, B. Arda et al., Pooled analysis of 899 nosocomial meningitis episodes from Turkey, Turk, J. Med. Sci, pp.47-76, 2017.

O. R. Sipahi, Economics of antibiotic resistance, Expert Review of Anti-infective Therapy, vol.21, issue.4, pp.523-562, 2008.
DOI : 10.1016/S0924-8579(02)00361-8

M. S. Tasbakan, H. Pullukcu, O. R. Sipahi, M. I. Tasbakan, S. Aydemir et al., Pneumonia?, Journal of Chemotherapy, vol.18, issue.1, pp.345-354, 2011.
DOI : 10.1016/j.jinf.2009.02.009

J. A. Wadi, J. A. , and M. A. , Multidrug resistant Acinetobacter nosocomial meningitis treated successfully with parenteral tigecycline, Annals of Saudi Medicine, vol.27, issue.6, pp.456-464, 2007.
DOI : 10.4103/0256-4947.51451

E. E. Tutuncu, F. Kuscu, Y. Gurbuz, B. Ozturk, A. Haykir et al., Tigecycline use in two cases with multidrug-resistant Acinetobacter baumannii meningitis, International Journal of Infectious Diseases, vol.14, pp.224-230, 2010.
DOI : 10.1016/j.ijid.2009.07.022

URL : https://doi.org/10.1016/j.ijid.2009.07.022

W. Y. Kim, J. Y. Moon, J. W. Huh, S. H. Choi, C. M. Lim et al., Comparable Efficacy of Tigecycline versus Colistin Therapy for Multidrug-Resistant and Extensively Drug-Resistant Acinetobacter baumannii Pneumonia in Critically Ill Patients, PLOS ONE, vol.59, issue.1, p.150642, 2016.
DOI : 10.1371/journal.pone.0150642.s001

URL : http://doi.org/10.1371/journal.pone.0150642

Y. C. Chuang, Y. C. Cheng, W. H. Sheng, H. Y. Sun, J. T. Wang et al., Effectiveness of tigecycline-based versus colistin-based therapy for treatment of pneumonia caused by multidrug-resistant Acinetobacter baumannii in a critical setting: a matched cohort analysis, BMC Infect. Dis, vol.102, p.14, 2014.

O. R. Sipahi, H. Kahraman, S. Mermer, H. Pullukcu, M. Tasbakan et al.,

S. Aydemir and . Ulusoy, Tigecycline in the management of post-neurosurgical spondylodiscitis: a review of eight cases, Int. J. Infect. Dis, vol.23, pp.16-25, 2014.

O. R. Sipahi, S. Bardak, T. Turhan, B. Arda, H. Pullukcu et al.,

M. Yurtseven, S. Zileli, and . Ulusoy, Linezolid in the treatment of methicillin-resistant staphylococcal postneurosurgical meningitis: a series of 17 cases. Scand, J. Infect. Dis, pp.43-757, 2011.

U. J. Kim, H. K. Kim, J. H. An, S. K. Cho, K. H. Park et al., Update on the Epidemiology, Treatment, and Outcomes of Carbapenem-resistant Acinetobacter infections, pp.50-87, 2014.

C. Buke, O. R. Sipahi, T. Yurtseven, and M. Zileli, High dose of intrathecal netilmicin in the treatment of nosocomial Acinetobacter baumannii meningitis, Journal of Infection, vol.51, issue.5, pp.51-420, 2005.
DOI : 10.1016/j.jinf.2005.02.011

B. N. Kim, A. Y. Peleg, T. P. Lodise, J. Lipman, R. Li et al., Management of meningitis due to antibiotic-resistant Acinetobacter species, The Lancet Infectious Diseases, vol.9, issue.4, pp.245-55, 2009.
DOI : 10.1016/S1473-3099(09)70055-6

I. Kooli, H. B. Brahim, M. Kilani, C. Gannouni, A. Aouam et al.,

. Chakroun, Successful treatment of postoperative multidrug-resistant Acinetobacter baumannii meningitis by tigecycline, J. Glob. Antimicrob. Resist, vol.5, pp.62-65, 2016.

G. D. Fang, W. J. Weiss, W. J. , and W. M. Scheld, Comparative efficacy of GAR-936, a novel glycylcycline, alone and in combination with vancomycin against highly penicillin-resistant Streptococcus pneumoniae experimental meningitis in rabbits, Abstracts of the fortieth Interscience Conference on Antimicrobials and Chemotherapy (ICAAC), p.51, 2000.

D. Yahav, A. Lador, M. Paul, M. , and L. Leibovici, Efficacy and safety of tigecycline: a systematic review and meta-analysis, Journal of Antimicrobial Chemotherapy, vol.153, issue.Suppl 4, pp.1963-71, 2011.
DOI : 10.7326/0003-4819-153-3-201008030-00006

P. C. Mcgovern, M. Wible, A. El-tahtawy, P. Biswas, and R. D. Meyer, All-cause mortality imbalance in the tigecycline phase 3 and 4 clinical trials, International Journal of Antimicrobial Agents, vol.41, issue.5, pp.463-470, 2013.
DOI : 10.1016/j.ijantimicag.2013.01.020

J. Garner, CDC definitions for nosocomial infections APIC infection control and applied epidemiology: principles and practice. St Louis: Mosby, pp.1-20, 1996.

C. Pallotto, M. Fiorio, A. D. Avolio, A. Sgrelli, F. Baldelli et al., Performance Standards for Antimicrobial Susceptibility Cerebrospinal fluid penetration of tigecycline. Scand, J. Infect. Dis, pp.46-69, 2014.
DOI : 10.3109/00365548.2013.837957

C. Lengerke, M. Haap, F. Mayer, L. Kanz, M. Kinzig et al., Low tigecycline concentrations in the cerebrospinal fluid of a neutropenicpatient with inflamed meninges

, Antimicrob. Agents Chemother, vol.55, pp.449-50, 2011.

L. Lauretti, Q. G. D-'alessandris, M. Fantoni, T. D. Inzeo, E. Fernandez et al., Journal of Neurosurgery, vol.76, issue.2, pp.370-373, 2017.
DOI : 10.4103/0255-0857.115653

Y. Wu, K. Chen, J. Zhao, Q. Wang, and . Zhou, Intraventricular administration of tigecycline for the treatment of multidrug-resistant bacterial meningitis after craniotomy: a case report, Journal of Chemotherapy, vol.14, issue.3, pp.30-49, 2017.
DOI : 10.1016/j.ijantimicag.2008.07.031

Y. Q. Fang, R. C. Zhan, W. Jia, B. Q. Zhang, and J. J. Wang, A case report of intraventricular tigecycline therapy for intracranial infection with extremely drug resistant Acinetobacter baumannii, Medicine, vol.96, issue.31, pp.96-7703, 2017.
DOI : 10.1097/MD.0000000000007703

M. E. Falagas, I. A. Bliziotis, and I. A. Tam, Intraventricular or intrathecal use of polymyxins in patients with Gram-negative meningitis: a systematic review of the available evidence, International Journal of Antimicrobial Agents, vol.29, issue.1, pp.29-38, 2007.
DOI : 10.1016/j.ijantimicag.2006.08.024

G. Fotakopoulos, D. Makris, M. Chatzi, E. Tsimitrea, E. Zakynthinos et al., Outcomes in meningitis/ventriculitis treated with intravenous or intraventricular plus intravenous colistin, Acta Neurochirurgica, vol.57, issue.4, pp.603-613, 2016.
DOI : 10.1128/AAC.01461-12

T. Khawcharoenporn, A. Apisarnthanarak, and L. M. Mundy, Intrathecal colistin for drug-resistant

, Acinetobacter baumannii central nervous system infection: a case series and systematic review, Clin. Microbiol. Infect, vol.16, pp.888-94, 2010.

G. A. March and M. A. Bratos, A meta-analysis of in vitro antibiotic synergy against Acinetobacter baumannii, Journal of Microbiological Methods, vol.119
DOI : 10.1016/j.mimet.2015.09.014

, J. Microbiol. Methods, vol.119, pp.31-37, 2015.

J. C. Stoltzfus, Logistic Regression: A Brief Primer, Academic Emergency Medicine, vol.115, issue.10, pp.1099-104, 2011.
DOI : 10.1161/CIRCULATIONAHA.105.594929

B. Ceylan, F. Arslan, O. R. Sipahi, M. Sunbul, B. Ormen et al.,