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Syndromes paranéoplasiques en ophtalmologie

Abstract : Paraneoplastic syndromes involving the visual system are a heterogeneous group of disorders occurring in the setting of systemic malignancy. Although these syndromes are rare, the clinical manifestations can herald an unsuspected, underlying malignancy. The associated antibodies and histopathology of each syndrome are presented to help in the understanding of these autoimmune phenomena. Outlined in this review article are diagnostic features useful in differentiating cancer-associated retinopathy, melanoma-associated retinopathy, paraneoplastic polymorphous vitelliform maculopathy, bilateral diffuse uveal melanocytic proliferation and paraneoplastic neurologic syndromes such as optic neuropathy, opsoclonus-myoclonus, Lambert-Eaton myasthenia and paraneoplastic cerebellar degeneration.
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-01834085
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, July 10, 2018 - 11:17:05 AM
Last modification on : Tuesday, May 26, 2020 - 3:41:02 AM

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A Bussat, S Langner-Lemercier, A Salmon, F Mouriaux. Syndromes paranéoplasiques en ophtalmologie. Journal Français D'Ophtalmologie, Elsevier Masson, 2018, 41 (6), pp.554-559. ⟨10.1016/j.jfo.2018.02.003⟩. ⟨hal-01834085⟩

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