Experimental models of developmental programming: consequences of exposure to an energy rich diet during development, The Journal of Physiology, vol.7, issue.Suppl. 3, pp.3-8, 2005. ,
DOI : 10.1038/85354
WEIGHT IN INFANCY 740 AND DEATH FROM ISCHAEMIC HEART DISEASE. The Lancet, 1989. ,
Critical Periods of Vulnerability for the Developing Nervous 743 System: Evidence from Humans and Animal Models. Environ Health Perspect, 2000. ,
, Jun, vol.1108, issue.s3, pp.511-544
The influence of children???s diet on their cognition and behavior, European Journal of Nutrition, vol.23, issue.1, pp.25-37, 2008. ,
DOI : 10.1001/archpedi.1996.02170350091016
Maternal Macronutrient Consumption and 748 the Developmental Origins of Metabolic Disease in the Offspring, Int J Mol Sci, p.749, 2017. ,
, Jul, vol.618, issue.7, p.1451
Maternal High-Fat Diet and 751 Fetal Programming: Increased Proliferation of Hypothalamic Peptide-Producing 752 ,
, , pp.12107-12126, 2008.
Developmental programming of obesity in mammals. Exp 755 Physiol, pp.287-98, 2007. ,
Maternal nutritional history predicts 757 obesity in adult offspring independent of postnatal diet: Maternal high fat nutrition 758 and obesity in offspring, J Physiol. Feb, vol.15587, issue.4, pp.905-920, 2009. ,
Established maternal obesity in the rat reprograms 760 hypothalamic appetite regulators and leptin signaling at birth, Int J Obes, 2009. ,
DOI : 10.1038/ijo.2008.213
URL : http://www.nature.com/ijo/journal/v33/n1/pdf/ijo2008213a.pdf
, Perinatal Maternal Fat, p.763
, Intake Affects Metabolism and Hippocampal Function in the Offspring
, , pp.189-202, 2008.
, , p.766
, Melanocortin Expression and Inflammatory Pathways in Fetal Offspring of 767 Nonhuman Primates Fed a High-Fat Diet, Endocrinology. 2010, vol.151, issue.4, pp.1622-768
, Life 770 Programming and Neurodevelopmental Disorders, 2010.
Prenatal, but 773 not early postnatal, exposure to a Western diet improves spatial memory of pigs 774 later in life and is paired with changes in maternal prepartum blood lipid levels. 775 FASEB J [Internet], p.776, 2016. ,
A 778 maternal Western diet during gestation and lactation modifies offspring's 779 microbiota activity, blood lipid levels, cognitive responses, and hippocampal 780 neurogenesis in Yucatan pigs, p.781, 201601015. ,
Enduring consequences of maternal obesity for brain inflammation and behavior of offspring, The FASEB Journal, vol.24, issue.6, pp.2104-2119, 2010. ,
DOI : 10.1203/PDR.0b013e3181a7c121
Ursolic acid improves high fat 784 diet-induced cognitive impairments by blocking endoplasmic reticulum stress and 785 ,
, I?B kinase ?/nuclear factor-?B-mediated inflammatory pathways in mice, Brain, vol.786
, , pp.1658-67, 2011.
Maternal high fat diet consumption during the perinatal period programs offspring behavior, Physiology & Behavior, vol.123, pp.236-789, 2014. ,
DOI : 10.1016/j.physbeh.2012.07.014
Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring, Neurochemistry International, vol.57, issue.3, pp.235-282, 2010. ,
DOI : 10.1016/j.neuint.2010.05.015
Imaging of Brain Dopamine Pathways, Journal of Addiction Medicine, vol.3, issue.1, pp.8-18, 2009. ,
DOI : 10.1097/ADM.0b013e31819a86f7
High-Fat Diet Exposure Increases Dopamine D2 Receptor and Decreases Dopamine Transporter Receptor Binding Density in the Nucleus Accumbens and Caudate Putamen of Mice, Neurochemical Research, vol.81, issue.11, pp.598-798, 2008. ,
DOI : 10.1152/ajpregu.00602.2002
Maternal high-fat intake alters presynaptic regulation of dopamine in the nucleus accumbens and increases motivation for fat rewards in the offspring, Neuroscience, vol.176, pp.225-261, 2011. ,
DOI : 10.1016/j.neuroscience.2010.12.037
Maternal high fat diet during the perinatal period alters mesocorticolimbic dopamine in the adult rat offspring: reduction in the behavioral responses to repeated amphetamine administration, Psychopharmacology, vol.83, issue.4, pp.83-94, 2008. ,
DOI : 10.1111/j.1530-0277.1999.tb04056.x
Brain dopamine and obesity, The Lancet, vol.357, issue.9253, pp.354-361, 2001. ,
DOI : 10.1016/S0140-6736(00)03643-6
Changes in Brain Activity After a Diet-Induced Obesity, Obesity, vol.21, issue.4, pp.749-56, 2011. ,
DOI : 10.1016/j.biopsych.2005.05.043
URL : https://hal.archives-ouvertes.fr/hal-01409421
Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors, NeuroImage, vol.42, issue.4, pp.1537-1580, 2008. ,
DOI : 10.1016/j.neuroimage.2008.06.002
Refined 814 food addiction: A classic substance use disorder Med Hypotheses, 2009. ,
Fructose: Metabolic, Hedonic, and Societal Parallels with Ethanol, Journal of the American Dietetic Association, vol.110, issue.9, p.817 ,
DOI : 10.1016/j.jada.2010.06.008
, Diet Assoc, vol.110, issue.9, pp.1307-1328, 2010.
The Addiction Potential of Hyperpalatable Foods, Current Drug Abuse Reviewse, vol.4, issue.3, pp.140-145, 2011. ,
DOI : 10.2174/1874473711104030140
The Pig as a Model for Human Nutrition, Annual Review of Nutrition, vol.7, issue.1, p.821, 1987. ,
DOI : 10.1146/annurev.nu.07.070187.002045
Quantitative growth and development of human brain. Arch Dis 823 Child, pp.757-67, 1973. ,
Comparative aspects of the brain growth spurt, Early Human Development, vol.3, issue.1, pp.79-83, 1979. ,
DOI : 10.1016/0378-3782(79)90022-7
The pig as a model for the study of obesity and of 827 control of food intake: a review, Yale J Biol Med, vol.52, issue.3, pp.307-336, 1979. ,
Neuroanatomical bases of spatial memory. Brain 829 Res, pp.307-327, 1980. ,
Obesity and vulnerability of the CNS, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1792, issue.5, p.831 ,
DOI : 10.1016/j.bbadis.2008.10.004
URL : https://hal.archives-ouvertes.fr/hal-00562869
, Biochim Biophys Acta BBA - Mol Basis Dis, vol.1792, issue.5, pp.395-400, 2009.
Western diet consumption and cognitive impairment: Links to hippocampal dysfunction and obesity, Physiology & Behavior, vol.103, issue.1, pp.59-834 ,
DOI : 10.1016/j.physbeh.2010.12.003
The longer-term impacts of Western diet on human 836 cognition and the brain, Appetite. 2013, vol.63, pp.119-147 ,
The Effect of Early Human Diet on Caudate Volumes and IQ, Pediatric Research, vol.20, issue.3, pp.308-839, 2008. ,
DOI : 10.1002/hbm.10131
Beyond the reward hypothesis: alternative functions of nucleus accumbens dopamine, Current Opinion in Pharmacology, vol.5, issue.1, 2005. ,
DOI : 10.1016/j.coph.2004.09.004
, Feb, vol.5, issue.1, pp.34-41
Production of Short Chain Fatty Acids by the Intestinal Microflora During the First 2 Years of Human Life, Journal of Pediatric Gastroenterology and Nutrition, vol.15, issue.4, pp.395-403, 1992845-11. ,
DOI : 10.1097/00005176-199211000-00005
, Critical review evaluating the pig as a model for human nutritional physiology, p.848
, Nutr Res Rev, pp.1-31, 2016.
850 Maternal short-chain fructo-oligosaccharide supplementation increases intestinal 851 cytokine secretion, goblet cell number, butyrate concentration and Lawsonia 852 intracellularis humoral vaccine response in weaned pigs, Br J Nutr, 2017. ,
Review article, Journal of Advanced Nursing, vol.30, issue.3, pp.349-63, 2006. ,
DOI : 10.1046/j.1365-2648.1999.1143f.x
Effects of chronic intake of starch-, glucose- and fructose-containing diets on eating behaviour in adult minipigs, Applied Animal Behaviour Science, vol.157, pp.61-71, 2014. ,
DOI : 10.1016/j.applanim.2014.05.010
Working and reference memory of pigs in the spatial holeboard discrimination task, Behavioural Brain Research, vol.205, issue.1, pp.303-309, 2009. ,
DOI : 10.1016/j.bbr.2009.06.014
Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research, Neuroscience & Biobehavioral Reviews, vol.35, issue.3, pp.437-51, 2011. ,
DOI : 10.1016/j.neubiorev.2010.05.004
Working and reference memory of pigs (Sus scrofa domesticus) in a holeboard 866 spatial discrimination task: the influence of environmental enrichment, Anim Cogn, vol.86716, issue.5, pp.845-50, 2013. ,
Assessing learning and memory in pigs, Animal Cognition, vol.111, issue.4, p.869 ,
DOI : 10.1016/j.applanim.2007.05.010
, Anim Cogn, vol.14, issue.2, pp.151-73, 2011.
OsiriX: An Open-Source Software for Navigating in 871 ,
, J Digit Imaging, vol.17, issue.3, pp.205-221, 2004.
Combined 873 compared to dissociated oral and intestinal sucrose stimuli induce different brain 874 hedonic processes, Front Psychol [Internet], vol.5, 2014. ,
A three- 878 dimensional digital segmented and deformable brain atlas of the domestic pig. J 879 Neurosci Methods, pp.102-111, 2010. ,
A computed tomography scan 881 application to evaluate adiposity in a minipig model of human obesity, Br J Nutr, vol.882104, issue.11, pp.1719-1747, 2010. ,
Dietary ??-lactalbumin supplementation alleviates normocaloric western diet-induced glucose intolerance in G??ttingen minipigs, Obesity, vol.134, issue.2, pp.415-436, 2015. ,
DOI : 10.1038/ejcn.2012.48
Evaluation of different methods for assessment of insulin sensitivity in G??ttingen minipigs: introduction of a new, simpler method, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, vol.281, issue.4, pp.1195-201, 2009. ,
DOI : 10.1111/j.0959-9673.2004.00394.x
Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose., Journal of Clinical Investigation, vol.68, issue.6, pp.1456-67, 1981. ,
DOI : 10.1172/JCI110398
Consensus 896 Nomenclature for in vivo Imaging of Reversibly Binding Radioligands. J Cereb Blood 897 Flow Metab, pp.1533-1542, 2007. ,
Quantitative autoradiography of ligands for dopamine receptors and transporters in brain of G??ttingen minipig: Comparison with results in vivo, Synapse, vol.1, issue.4, pp.211-220, 2006. ,
DOI : 10.1038/sj.npp.1380111
Effects of environmental enrichment on cognitive performance of pigs in a spatial holeboard discrimination task, Animal Cognition, vol.15, issue.2, pp.271-83, 2016. ,
DOI : 10.1002/9780470751046.ch1
Female and male pigs??? performance in a spatial holeboard and judgment bias task, Applied Animal Behaviour Science, vol.191, pp.5-16 ,
DOI : 10.1016/j.applanim.2017.01.016
Effects of diet on behaviour and cognition in children, British Journal of Nutrition, vol.125, issue.S2, p.908, 2004. ,
DOI : 10.1016/S0278-5846(99)00063-9
910 Effects of Diets High in Sucrose or Aspartame on The Behavior and Cognitive 911 Performance of Children, N Engl J Med Feb, vol.3330, issue.5, pp.301-308, 1994. ,
Chronic Consumption of a High-Fat Diet during Pregnancy Causes Perturbations in the Serotonergic System and Increased Anxiety-Like Behavior in Nonhuman Primate Offspring, Journal of Neuroscience, vol.30, issue.10, pp.3826-3856, 2010. ,
DOI : 10.1523/JNEUROSCI.5560-09.2010
Learning under stress: how does it 917 work? Trends Cogn Sci, pp.152-160, 2006. ,
The Concept of the Ventral Striatum in Nonhuman Primates, Annals of the New York Academy of Sciences, vol.10, issue.4, pp.33-48, 1999. ,
DOI : 10.1002/cne.903460305
Discrete neurochemical coding of distinguishable motivational 921 processes: insights from nucleus accumbens control of feeding. 922 Psychopharmacology (Berl), pp.439-59, 2007. ,
Dissociations between appetitive and consummatory 924 responses by pharmacological manipulations of reward-relevant brain regions, p.925 ,
, Behav Neurosci, vol.110, issue.2, pp.331-376, 1996.
Compartmental distribution of ventral striatal neurons projecting to the mesencephalon in the rat, The Journal of Neuroscience, vol.12, issue.6, pp.2079-103, 1992. ,
DOI : 10.1523/JNEUROSCI.12-06-02079.1992
Distinct prefrontal cortical regions negatively regulate evoked 930 activity in nucleus accumbens subregions, Int J Neuropsychopharmacol, p.2012 ,
Reduction of Prefrontal Cortex Glucose Metabolism Common to Three 933 Types of Depression. Arch Gen Psychiatry, pp.243-934, 1989. ,
Left 935 prefrontal glucose hypometabolism in the depressed state: a confirmation. Am J 936 Psychiatry, pp.1313-1320, 1990. ,
PET measurements of brain glucose metabolism and blood flow in 938 major depressive disorder: a critical review, Acta Psychiatr Scand, 2000. ,
Perinatal Exposure to High-Fat Diet Programs 941 Energy Balance, Metabolism and Behavior in Adulthood, Neuroendocrinology, vol.94293, issue.1, pp.1-8, 2011. ,
Less activation 944 in the left dorsolateral prefrontal cortex in the reanalysis of the response to a meal 945 in obese than in lean women and its association with successful weight loss, Am J, p.946 ,
, Clin Nutr, vol.86, issue.3, pp.573-582, 2007.
Relation of reward from food intake and anticipated food intake to obesity: A functional magnetic resonance imaging study., Journal of Abnormal Psychology, vol.117, issue.4, pp.924-959, 2008. ,
DOI : 10.1037/a0013600
Prolonged High Fat Diet 951 Reduces Dopamine Reuptake without Altering DAT Gene Expression. Simon SA, 952 editor. PLoS ONE Diet-induced 954 obesity: dopamine transporter function, impulsivity and motivation Available from: 956 http, Int J Obes, vol.837, issue.9558, pp.2005-957, 2013. ,
Quantitative autoradiography of ligands for dopamine receptors and transporters in brain of G??ttingen minipig: Comparison with results in vivo, Synapse, vol.1, issue.4, pp.211-220, 2006. ,
DOI : 10.1038/sj.npp.1380111
Dopamine transporter and D2 receptor binding densities in mice prone or resistant to chronic high fat diet-induced obesity, Behavioural Brain Research, vol.175, issue.2, pp.415-424, 2006. ,
DOI : 10.1016/j.bbr.2006.08.034
Prolonged High Fat Diet 965 Reduces Dopamine Reuptake without Altering DAT Gene Expression, PLOS ONE, vol.9668, issue.3, p.58251, 2013. ,
Correlation between body mass index and striatal dopamine transporter availability in healthy volunteers???A SPECT study, NeuroImage, vol.40, issue.1, pp.275-284, 2008. ,
DOI : 10.1016/j.neuroimage.2007.11.007
Reduced Serotonin Reuptake Transporter (SERT) Function Causes Insulin Resistance and Hepatic Steatosis Independent of Food Intake, PLoS ONE, vol.4, issue.3, pp.32511-973, 2012. ,
DOI : 10.1371/journal.pone.0032511.s005
Role of 974 the parahippocampal cortex in memory for the configuration but not the identity of 975 objects: converging evidence from patients with selective thermal lesions and fMRI. 976 Front Hum Neurosci [Internet] Available from: 977 http, 2015. ,
The role of the parahippocampal cortex in cognition. 979 Trends Cogn Sci, pp.379-90, 2013. ,
Flavour preference 981 acquired via a beverage-induced conditioning and its transposition to solid food, p.982 ,
, Sucrose but not maltodextrin or saccharin induced significant flavour preferences 983 in pigs, Appl Anim Behav Sci. 2012, vol.136, issue.1, pp.26-36
, , p.985
, Predictive Adaptive Response hypothesis: Developmental plasticity and the PAR 986 response, J Physiol, vol.592, issue.11, pp.2357-68, 2014.
Programming of intermediary metabolism, Molecular and Cellular Endocrinology, vol.185, issue.1-2, pp.81-91, 2001. ,
DOI : 10.1016/S0303-7207(01)00627-X
, Developmental Programming in Response to Maternal 990
Available from: 991 http, 2011. ,
Long-term consequences of maternal high-fat feeding on hypothalamic leptin sensitivity and diet-induced obesity in the offspring, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, vol.293, issue.3, pp.1056-62, 2007. ,
DOI : 10.1113/jphysiol.2005.100313
Unexpected Long-Term Protection of Adult Offspring Born to High-Fat Fed Dams against Obesity Induced by a Sucrose-Rich Diet, PLoS ONE, vol.242, issue.3, pp.18043-1000, 2011. ,
DOI : 10.1371/journal.pone.0018043.s001
URL : https://hal.archives-ouvertes.fr/hal-00719394
Predictive Adaptive Responses to Maternal High-Fat Diet Prevent, 1001. ,
, Endothelial Dysfunction but Not Hypertension in Adult Rat Offspring. Circulation. Aug, vol.1002110, issue.239, pp.1097-102, 2004.
Maternal obesity is necessary for 1004 programming effect of high-fat diet on offspring. AJP Regul Integr Comp Physiol, pp.1464-72, 1005. ,
An obesity-associated gut microbiome with increased capacity for energy harvest, Nature, vol.20, issue.7122, pp.1027-131, 1008. ,
DOI : 10.1093/bioinformatics/bth078
Stereotaxic atlas of the pig brain, Stereotaxic atlas of the pig brain, pp.1-137, 1010. ,
DOI : 10.1016/S0361-9230(99)00012-X
, N_Immobile as occurrences of immobility, duration as test duration, Explore_Wall 1034 representing the time of wall exploration by animals, and Index as index of performance of 1035
, C) Individuals graphic from PCA analysis for maze test. With 5 WD individuals 1036 (red) and 5 SD individuals (black), p.1037
, Binding potential (mean ± SEM) of DAT in VOIs in WD (black) and SD 1054 (white) animals. *, P
, overweight animals (hatched) animals. D) Dorsal backfat thickness evolution between lean 1062 and overweight status in SD (grey) and WD (black) animals