Fluoro- and Chloroferrocene From 2-to 3-Substituted Derivatives

Mehdi Tazi (1) , Madani Hedidi (1, 2) , William Erb (1) , Yury S. Halauko (3, 4) , Oleg A. Ivashkevich (4) , Vadim E. Matulis (4) , Thierry Roisnel (1) , Vincent Dorcet (1) , Ghenia Bentabed-Ababsa (5) , Florence Mongin (1)

1 ISCR - Institut des Sciences Chimiques de Rennes
2 UHBC - Université Hassiba Ben Bouali de Chlef
3 UNESCO Chair of Belarusian State University
4 Belarusian State University
5 Université d'Oran 1 Ahmed Ben Bella [Oran]

The ferrocene halogen "dance" has been deemed hardly controllable. Here, we describe the first efficient examples of this reaction. Conversion of 1-fluoro-2-iodo (or 1-chloro-2-iodo) to 1-fluoro-3-iodo (or 1-chloro-3-iodo) ferrocenes was ensured by suitably protecting the free 5 position.

Domains: Chemical Sciences

Mehdi Tazi, Madani Hedidi, William Erb, Yury S. Halauko, Oleg A. Ivashkevich, et al.. Fluoro- and Chloroferrocene From 2-to 3-Substituted Derivatives. Organometallics, 2018, 37 (14), pp.2207-2211. ⟨10.1021/acs.organomet.8b00384⟩. ⟨hal-01861424⟩