V. Agier, P. Oliviero, J. Lainé, L. 'hermitte-stead, C. Girard et al., Lombè s A. 2012. Defective mitochondrial fusion, altered respiratory function, and distorted cristae structure in skin fibroblasts with heterozygous OPA1 mutations, Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease, vol.1822, p.22800932

Y. Baba, K. Nosho, K. Shima, N. Irahara, S. Kure et al., Aurora-A expression is independently associated with chromosomal instability in colorectal cancer, Neoplasia, vol.11, p.19412426, 2009.

V. Bavetsias and S. Linardopoulos, Aurora kinase inhibitors: current status and outlook, Frontiers in Oncology, vol.5, p.26734566, 2015.

E. J. Belt, E. A. Velde, O. Krijgsman, R. P. Brosens, M. Tijssen et al., High lymph node yield is related to microsatellite instability in colon cancer, Annals of surgical oncology, vol.19, p.21989661, 2012.

G. Bertolin, R. Ferrando-miguel, M. Jacoupy, S. Traver, K. Grenier et al., The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance, Autophagy, vol.9, p.24149440, 2013.

G. Bertolin, F. Sizaire, G. Herbomel, D. Reboutier, C. Prigent et al., A FRET biosensor reveals spatiotemporal activation and functions of Aurora kinase A in living cells, Nature Communications, vol.7, p.27624869, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01394773

J. R. Bischoff, L. Anderson, Y. Zhu, K. Mossie, L. Ng et al., A homologue of Drosophila Aurora kinase is oncogenic and amplified in human colorectal cancers, The EMBO Journal, vol.17, p.9606188, 1998.

S. Bolte, C. , and F. P. , A guided tour into subcellular colocalization analysis in light microscopy, Journal of Microscopy, vol.224, p.17210054, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00132481

A. L. Bulteau, M. Moreau, A. Saunois, C. Nizard, and B. Friguet, Algae extract-mediated stimulation and protection of proteasome activity within human keratinocytes exposed to UVA and UVB irradiation, Antioxidants & Redox Signaling, vol.8, p.16487047, 2006.

B. Carvalho, A. H. Sillars-hardebol, C. Postma, S. Mongera, J. Droste et al., Colorectal adenoma to carcinoma progression is accompanied by changes in gene expression associated with ageing, chromosomal instability, and fatty acid metabolism, Cellular Oncology, vol.35, pp.53-63, 2012.

A. Chacinska, C. M. Koehler, D. Milenkovic, T. Lithgow, and N. Pfanner, Importing mitochondrial proteins: machineries and mechanisms, Cell, vol.138, pp.1-9703392, 2009.

J. Y. Cremet, S. Descamps, F. Vé-rite, A. Martin, and C. Prigent, Preparation and characterization of a human aurora-A kinase monoclonal antibody, Molecular and Cellular Biochemistry, vol.243, p.12619897, 2003.
URL : https://hal.archives-ouvertes.fr/inserm-00966484

J. J. Driscoll and R. D. Chowdhury, Molecular crosstalk between the proteasome, aggresomes and autophagy: translational potential and clinical implications, Cancer Letters, vol.325, p.22781397, 2012.

A. W. Ferree, K. Trudeau, E. Zik, I. Y. Benador, G. Twig et al., MitoTimer probe reveals the impact of autophagy, fusion, and motility on subcellular distribution of young and old mitochondrial protein and on relative mitochondrial protein age, Autophagy, vol.9, p.24149000, 2013.

G. Griffiths, A. Mcdowall, R. Back, and J. Dubochet, On the preparation of cryosections for immunocytochemistry, Journal of Ultrastructure Research, vol.89, issue.84, p.6544882, 1984.

G. Gö-rgü-n, E. Calabrese, T. Hideshima, J. Ecsedy, G. Perrone et al., A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma, Blood, vol.115, p.20382844, 2010.

H. Hoitzing, I. G. Johnston, and N. S. Jones, What is the function of mitochondrial networks? A theoretical assessment of hypotheses and proposal for future research, BioEssays, vol.37, p.25847815, 2015.

. Huang-daw, B. T. Sherman, and R. A. Lempicki, Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources, Nature Protocols, vol.4, p.19131956, 2009.

. Huang-daw, B. T. Sherman, and R. A. Lempicki, Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists, Nucleic Acids Research, vol.37, p.19033363, 2009.

J. R. Hughes, A. M. Meireles, K. H. Fisher, A. Garcia, P. R. Antrobus et al., A microtubule interactome: complexes with roles in cell cycle and mitosis, PLoS Biology, vol.6, p.18433294, 2008.

S. Karniely and O. Pines, Single translation-dual destination: mechanisms of dual protein targeting in eukaryotes, EMBO Reports, vol.6, p.15864293, 2005.

D. F. Kashatus, K. H. Lim, D. C. Brady, N. L. Pershing, A. D. Cox et al., RALA and RALBP1 regulate mitochondrial fission at mitosis, Nature Cell Biology, vol.13, p.21822277, 2011.

S. Kondo and R. Ueda, Highly improved gene targeting by germline-specific Cas9 expression in Drosophila, Genetics, vol.195, p.24002648, 2013.

W. J. Koopman, H. J. Visch, S. Verkaart, L. W. Van-den-heuvel, J. A. Smeitink et al., Mitochondrial network complexity and pathological decrease in complex I activity are tightly correlated in isolated human complex I deficiency, American Journal of Physiology-Cell Physiology, vol.289, p.15901599, 2005.

Y. J. Lee, S. Y. Jeong, M. Karbowski, C. L. Smith, and R. J. Youle, Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis, Molecular biology of the cell, vol.15, p.15356267, 2004.

K. H. Lim, D. C. Brady, D. F. Kashatus, B. B. Ancrile, C. J. Der et al., Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA, Molecular and Cellular Biology, vol.30, pp.508-523, 2010.

G. D. Matthews, N. Gur, W. J. Koopman, O. Pines, and L. Vardimon, Weak mitochondrial targeting sequence determines tissue-specific subcellular localization of glutamine synthetase in liver and brain cells, Journal of Cell Science, vol.123, pp.351-359, 2010.

P. Mishra, V. Carelli, G. Manfredi, and D. C. Chan, Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation, Cell Metabolism, vol.19, p.24703695, 2014.

P. Mishra and D. C. Chan, Metabolic regulation of mitochondrial dynamics, The Journal of Cell Biology, vol.212, p.26858267, 2016.

K. Mitra, C. Wunder, B. Roysam, G. Lin, and J. Lippincott-schwartz, A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase, PNAS, vol.106, p.19617534, 2009.

K. Mitra, Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation, BioEssays, vol.35, p.23943303, 2013.

W. Moon and F. Matsuzaki, Aurora A kinase negatively regulates Rho-kinase by phosphorylation in vivo, Biochemical and Biophysical Research Communications, vol.435, p.23685146, 2013.

A. Moore and A. Golden, Hypothesis: bifunctional mitochondrial proteins have centrosomal functions, Environmental and Molecular Mutagenesis, vol.50, p.9565650, 2009.

D. Mori, M. Yamada, Y. Mimori-kiyosue, Y. Shirai, A. Suzuki et al., An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics, Nature cell biology, vol.11, p.19668197, 2009.

Y. Nadler, R. L. Camp, C. Schwartz, D. L. Rimm, H. M. Kluger et al., Expression of Aurora A (but not Aurora B) is predictive of survival in breast cancer, Clinical cancer research : an official journal of the American Association for Cancer Research, vol.14, p.18628459, 2008.

K. Nakada, K. Inoue, T. Ono, K. Isobe, A. Ogura et al., Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA, Nature medicine, vol.7, p.11479626, 2001.

O. Nicolle, A. Burel, G. Griffiths, G. Michaux, and I. Kolotuev, Adaptation of Cryo-Sectioning for IEM labeling of asymmetric samples: a study using Caenorhabditis elegans: cryo-sectioning of asymmetric samples, Traffic, vol.16, pp.893-905, 2015.

A. S. Nikonova, I. Astsaturov, I. G. Serebriiskii, R. L. Dunbrack, and E. A. Golemis, Aurora A kinase (AURKA) in normal and pathological cell division, Cellular and Molecular Life Sciences, vol.70, p.22864622, 2013.

S. Padilla-parra and M. Tramier, FRET microscopy in the living cell: different approaches, strengths and weaknesses, BioEssays, vol.34, p.22415767, 2012.
URL : https://hal.archives-ouvertes.fr/inserm-00683306

A. H. Sillars-hardebol, B. Carvalho, M. Tijssen, J. A. Belië-n, M. De-wit et al., TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression, Gut, vol.61, p.22207630, 2012.

J. W. Slot and H. J. Geuze, Cryosectioning and immunolabeling, Nature protocols, vol.2, p.17947990, 2007.

D. Tondera, S. Grandemange, A. Jourdain, M. Karbowski, Y. Mattenberger et al., SLP-2 is required for stress-induced mitochondrial hyperfusion, The EMBO journal, vol.28, p.19360003, 2009.
URL : https://hal.archives-ouvertes.fr/hal-02184907

W. Treekitkarnmongkol, H. Katayama, K. Kai, K. Sasai, J. C. Jones et al., Aurora kinase-A overexpression in mouse mammary epithelium induces mammary adenocarcinomas harboring genetic alterations shared with human breast Cancer, Carcinogenesis, vol.37, p.27624071, 2016.

S. Vyas, E. Zaganjor, and M. C. Haigis, Mitochondria and cancer. Cell, vol.166, p.27471965, 2016.

F. N. Vö-gtle, S. Wortelkamp, R. P. Zahedi, D. Becker, C. Leidhold et al., Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability, Cell, vol.139, p.19837041, 2009.

T. Wai and T. Langer, Mitochondrial dynamics and metabolic regulation, Trends in Endocrinology & Metabolism, vol.27, p.26754340, 2016.

X. Wang, Y. X. Zhou, W. Qiao, Y. Tominaga, M. Ouchi et al., Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation, Oncogene, vol.25, p.16715125, 2006.

B. Westermann, Bioenergetic role of mitochondrial fusion and fission, Biochimica Et Biophysica Acta (BBA)-Bioenergetics, vol.1817, p.22409868, 2012.

D. Whitaker-menezes, U. E. Martinez-outschoorn, N. Flomenberg, R. C. Birbe, A. K. Witkiewicz et al., Hyperactivation of oxidative mitochondrial metabolism in epithelial Cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue, Cell Cycle, vol.10, p.22134189, 2011.

R. J. Youle and D. P. Narendra, Mechanisms of mitophagy, Nature reviews. Molecular cell biology, vol.12, p.21179058, 2011.

D. Zhang, T. Hirota, T. Marumoto, M. Shimizu, N. Kunitoku et al., Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models, Oncogene, vol.23, p.15480417, 2004.

F. Zheng, C. Yue, G. Li, B. He, W. Cheng et al., Nuclear AURKA acquires kinase-independent transactivating function to enhance breast Cancer stem cell phenotype, Nature Communications, vol.7, p.26782714, 2016.

K. Zhu, K. Dunner, and D. J. Mcconkey, Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells, Oncogene, vol.29, pp.1-9881538, 2010.