Emerging fields in chaperone proteins: A French workshop

Elisabetta Mileo (1) , Marianne Ilbert (1) , Alessandro Barducci (2) , Patricia Bordes (3) , Marie-Pierre Castanie-Cornet (3) , Cyrille Garnier (4, 5) , Pierre Genevaux (3) , Reynald Gillet (6) , Pierre Goloubinoff (7) , Françoise Ochsenbein (8) , Gilbert Richarme (9) , Chantal Lobbi-Nivol (1) , Marie-Thérèse Giudici-Orticoni (1) , Brigitte Gontero (1) , Olivier Genest (1)

1 BIP - Bioénergétique et Ingénierie des Protéines
2 CBS - Centre de Biochimie Structurale [Montpellier]
3 LMGM - Laboratoire de microbiologie et génétique moléculaires - UMR5100
4 MMDN - Mécanismes moléculaires dans les démences neurodégénératives
5 UR - Université de Rennes
6 IGDR - Institut de Génétique et Développement de Rennes
7 UNIL - Université de Lausanne = University of Lausanne
8 I2BC - Institut de Biologie Intégrative de la Cellule
9 LCBPT - UMR 8601 - Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques

The "Bioenergetique et Ingenierie des Proteines (BIP)" laboratory, CNRS (France), organized its first French workshop on molecular chaperone proteins and protein folding in November 2017. The goal of this workshop was to gather scientists working in France on chaperone proteins and protein folding. This initiative was a great success with excellent talks and fruitful discussions. The highlights were on the description of unexpected functions and post-translational regulation of known molecular chaperones (such as Hsp90, Hsp33, SecB, GroEL) and on state-of-the-art methods to tackle questions related to this theme, including Cryo-electron microscopy, Nuclear Magnetic Resonance (NMR), Electron Paramagnetic Resonance (EPR), simulation and modeling. We expect to organize a second workshop in two years that will include more scientists working in France in the chaperone field.

Keywords: Chaperone proteins; Multifunctionality; Plasticity; Folding/misfolding; Aggregation; Structural dynamics

Domains: Life Sciences [q-bio]; Genetics; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Biochemistry [q-bio.BM]

Elisabetta Mileo, Marianne Ilbert, Alessandro Barducci, Patricia Bordes, Marie-Pierre Castanie-Cornet, et al.. Emerging fields in chaperone proteins: A French workshop. Biochimie, 2018, 151, pp.159-165. ⟨10.1016/j.biochi.2018.06.004⟩. ⟨hal-01863220⟩