IGHV segment utilization in immunoglobulin gene rearrangement differentiates patients with anti-myelin-associated glycoprotein neuropathy from others immunoglobulin M-gammopathies

Jean-Sebastien Allain; Florian Thonier; Morgane Pihan; Marie-Laure Boulland; Sophie de Guibert; Vincent Launay; Anne-Violaine Doncker; Michel Ganard; Amyra Aliouat; Céline Pangault; Roch Houot; Marie de Tayrac; Thierry Lamy; Mikael Roussel; Thierry Fest; Olivier Decaux; Cedric Pastoret

doi:10.3324/haematol.2017.177444

Journal articles

IGHV segment utilization in immunoglobulin gene rearrangement differentiates patients with anti-myelin-associated glycoprotein neuropathy from others immunoglobulin M-gammopathies

Jean-Sebastien Allain ¹ Florian Thonier ² Morgane Pihan ³ Marie-Laure Boulland ² Sophie de Guibert ⁴ Vincent Launay ⁵ Anne-Violaine Doncker ⁶ Michel Ganard ^{4, 7} Amyra Aliouat ⁸ Céline Pangault ^{9, 2, 7} Roch Houot ^{9, 7, 4} Marie de Tayrac ^{8, 7} Thierry Lamy ^{9, 7, 4} Mikael Roussel ^{9, 2} Thierry Fest ^{9, 2, 7} Olivier Decaux ^{9, 7, 1} Cedric Pastoret ^{9, 2, 7, *}

* Corresponding author

1 Service de Médecine interne et immunologie clinique [Rennes] = internal medicine and clinical immunology [Rennes]

2 Pôle de Biologie - Laboratoire d'Hematologie [CHU Pontchaillou, Rennes]

3 Service de Neurologie [Rennes] = Neurology [Rennes]

4 Service d’Hématologie Clinique [Rennes]

5 Service d’Hématologie [CH Saint Brieuc]

6 Hopital Privé Sévigné [Cesson-Sévigné, France]

7 UR1 - Université de Rennes 1

8 Pôle de Biologie - Laboratoire de Bioinformatique Médicale [CHU Rennes]

9 MICMAC - Microenvironment, Cell Differentiation, Immunology and Cancer

Abstract : no abstract.

Keywords : immunoglobulin gene High throughput sequencing Monoclonal Gammopathy of Undetermined Significance Waldenström Macroglobulinemia MYD88 CXCR4 anti-MAG

Document type :

Journal articles

Domain :

Life Sciences [q-bio] / Genetics / Human genetics

Life Sciences [q-bio] / Immunology

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Submitted on : Wednesday, August 29, 2018 - 10:59:04 AM
Last modification on : Wednesday, March 30, 2022 - 2:39:16 PM
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IGHV segment utilization in immunoglobulin gene rearrangement differentiates patients with anti-myelin-associated glycoprotein neuropathy from others immunoglobulin M-gammopathies

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IGHV segment utilization in immunoglobulin gene rearrangement differentiates patients with anti-myelin-associated glycoprotein neuropathy from others immunoglobulin M-gammopathies

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