W. Aekplakorn, L. O. Chailurkit, and B. Ongphiphadhanakul, Relationship of serum bisphenol A with diabetes in the Thai population, National Health Examination Survey IV, J Diabetes, vol.7, issue.2, pp.240-249, 2009.

K. Agay-shay, D. Martinez, D. Valvi, R. Garcia-esteban, X. Basagana et al., Exposure to Endocrine-Disrupting Chemicals during Pregnancy and Weight at 7 Years of Age: A Multi-pollutant Approach, Environ Health Perspect, vol.123, issue.10, pp.1030-1037, 2015.

R. Ahmadkhaniha, M. Mansouri, M. Yunesian, K. Omidfar, M. Z. Jeddi et al., Association of urinary bisphenol a concentration with type-2 diabetes mellitus, J Environ Health Sci Eng, vol.12, issue.1, p.64, 2014.

S. Ahmed and E. Atlas, Bisphenol S-and bisphenol A-induced adipogenesis of murine preadipocytes occurs through direct peroxisome proliferator-activated receptor gamma activation, Int J Obes, vol.40, issue.10, pp.1566-1573, 2016.

A. Vieira, E. Soriano, S. Menes, L. Burks, D. Quesada et al., Bisphenol exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring, vol.118, pp.1243-1250, 2010.

A. García-arévalo, M. Quesada, I. Nadal, and Á. , Bisphenol-A treatment during pregnancy in mice: a new window of susceptibility for the development of diabetes in mothers later in life, Endocrinology, vol.156, issue.5, pp.1659-70, 2015.

B. M. Angle, R. P. Do, D. Ponzi, R. W. Stahlhut, B. E. Drury et al., Metabolic disruption in male mice due to fetal exposure to low but not high doses of bisphenol A (BPA): evidence for effects on body weight, food intake, adipocytes, leptin, adiponectin, insulin and glucose regulation, Reprod Toxicol, vol.42, pp.256-68, 2013.

, Annex XV Restriction Report-Proposal for a restriction-4.4'isopropylidenediphenol (bisphenol A; BPA), ANSES, 2014.

F. Ariemma, D. 'esposito, V. Liguoro, D. Oriente, F. Cabaro et al., Low-Dose Bisphenol-A Impairs Adipogenesis and Generates Dysfunctional 3T3-L1 Adipocytes, PLoS One, vol.4, issue.3, p.150762, 2016.

E. Atlas, L. Pope, M. G. Wade, A. Kawata, A. Boudreau et al., Bisphenol A increases aP2 expression in 3T3L1 by enhancing the transcriptional activity of nuclear receptors at the promoter, vol.3, pp.170-179, 2014.

D. J. Barker, The origins of the developmental origins theory, J Intern Med, vol.261, issue.5, pp.412-419, 2007.

R. P. Barros, J. Å. Gustafsson, and . ;-m-a-n-u-s-c-r-i-p-t, Estrogen receptors and the metabolic network, Cell Metab, vol.14, issue.3, pp.289-99, 2011.
DOI : 10.1016/j.cmet.2011.08.005
URL : https://doi.org/10.1016/j.cmet.2011.08.005

H. A. Beydoun, S. Khanal, A. B. Zonderman, and M. A. Beydoun, Sex differences in the association of urinary bisphenol-A concentration with selected indices of glucose homeostasis among U.S. adults, Ann Epidemiol, vol.24, issue.2, pp.90-97, 2014.

G. Biasiotto, I. Zanella, A. Masserdotti, R. Pedrazzani, M. Papa et al., Municipal wastewater affects adipose deposition in male mice and increases 3T3-L1 cell differentiation, Toxicol Appl Pharmacol, vol.297, pp.32-40, 2016.
DOI : 10.1016/j.taap.2016.02.023

R. Biemann, N. Santos, A. , N. Santos, A. Riemann et al., Endocrine disrupting chemicals affect the adipogenic differentiation of mesenchymal stem cells in distinct ontogenetic windows, Biochem Biophys Res Commun, vol.417, issue.2, pp.747-52, 2012.

J. G. Boucher, M. Husain, A. Rowan-carroll, A. Williams, C. L. Yauk et al., Identification of mechanisms of action of bisphenol a-induced human preadipocyte differentiation by transcriptional profiling, Vitro Effects of Bisphenol A ?-D-Glucuronide (BPA-G) on Adipogenesis in Human and Murine Preadipocytes, vol.22, pp.1287-93, 2014.

E. Carchia, I. Porreca, P. J. Almeida, D. Angelo, F. Cuomo et al., Evaluation of low doses BPA-induced perturbation of glycaemia by toxicogenomics points to a primary role of pancreatic islets and to the mechanism of toxicity, Cell Death Dis, vol.6, p.1959, 2015.

R. Chamorro-garcía, S. Kirchner, X. Li, A. Janesick, S. C. Casey et al., Bisphenol A diglycidyl ether induces adipogenic differentiation of multipotent stromal stem cells through a peroxisome proliferator-activated receptor gammaindependent mechanism, Environ Health Perspect, vol.120, issue.7, pp.984-993, 2012.

J. Choi, J. Eom, J. Kim, L. S. Kim, and Y. , Association between some endocrinedisrupting chemicals and childhood obesity in biological samples of young girls: a cross-sectional study, Environ Toxicol Pharmacol, vol.38, issue.1, pp.51-58, 2014.

C. Choi and P. Cohen, Adipose cross-talk with other cell types in health and disease, Exp Cell Res, 2017.
DOI : 10.1016/j.yexcr.2017.04.022

K. B. Delclos, Toxicity evaluation of bisphenol A administered by gavage to Sprague Dawley rats from gestation day 6 through postnatal day 90, Toxicol Sci, vol.139, issue.1, pp.174-97, 2014.

E. C. Dodds and W. Lawson, Synthetic oestrogenic agents without the Phenanthrene agents, Nature, vol.137, p.996, 1936.

D. J. Drucker, The biology of incretins, Cell Metabolism, vol.3, pp.153-165, 2006.

, Opinion on an Annex XV dossier proposing restrictions on Bisphenol A. Compiled version prepared by the ECHA Secretariat of RAC's opinion, SEAC's opinion, 2015.

, Scientific Opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs, EFSA journal, vol.13, issue.1, p.3978, 2015.

A. Foryst-ludwig, M. Clemenz, S. Hohmann, M. Hartge, C. Sprang et al., Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma, PLoS Genet, vol.4, issue.6, p.1000108, 2008.

M. García-arévalo, A. , P. , R. Santos, J. Quesada et al., , 2014.

M. García-arévalo, A. , P. Servitja, J. M. Boronat-belda, T. Merino et al., Maternal Exposure to Bisphenol-A During Pregnancy Increases Pancreatic ?-Cell Growth During Early Life in Male Mice Offspring, Endocrinology, vol.157, issue.11, pp.4158-4171, 2016.

H. Gong, X. Zhang, B. Cheng, Y. Sun, C. Li et al., Bisphenol A accelerates toxic amyloid formation of human islet amyloid polypeptide: a possible link between bisphenol A exposure and type 2 diabetes, PLoS One, vol.8, issue.1, p.54198, 2013.

, Guo S Insulin signaling, resistance, and metabolic syndrome : insights from mouse models into disease mechanisms, J Endocrinol, pp.220-221, 2014.

K. G. Harley, A. Schall, R. Chevrier, J. Tyler, K. Aguirre et al., Prenatal and postnatal bisphenol A exposure and body mass index in childhood in the CHAMACOS cohort, Environ Health Perspect, vol.121, issue.4, pp.514-534, 2013.

C. Héliès-toussaint, L. Peyre, C. Costanzo, M. C. Chagnon, and R. Rahmani, Is bisphenol S a safe substitute for bisphenol A in terms of metabolic function? An in vitro study, Toxicol Appl Pharmacol, vol.280, issue.2, pp.224-259, 2014.

A. L. Hevener, D. J. Clegg, and F. Mauvais-jarvis, Impaired estrogen receptor action in the pathogenesis of the metabolic syndrome, Mol Cell Endocrinol, vol.418, issue.3, pp.306-327, 2015.

J. Hu, S. Yang, Y. Wang, R. Goswami, C. Peng et al., Serum bisphenol A and progression of type 2 diabetic nephropathy: a 6-year prospective study, Acta Diabetol, vol.52, issue.6, pp.1135-1176, 2015.

S. Jayashree, D. Indumathi, N. Akilavalli, S. Sathish, J. Selvaraj et al., Effect of Bisphenol-A on insulin signal transduction and glucose oxidation in liver of adult male albino rat, Environ Toxicol Pharmacol, vol.35, issue.2, pp.300-310, 2013.

R. E. Jennings, A. A. Berry, J. P. Strutt, D. T. Gerrard, and N. A. Hanley, Human pancreas development, Development, vol.142, issue.18, pp.3126-3163, 2015.

A. D. Karelis, To be obese-does it matter if you are metabolically healthy?, Nat Rev Endocrinol, vol.7, issue.12, pp.699-700, 2011.

N. Khalil, J. R. Ebert, L. Wang, S. Belcher, M. Lee et al., Bisphenol A and cardiometabolic risk factors in obese children, Sci Total Environ, pp.470-471, 2014.

A. Ko, M. S. Hwang, J. H. Park, H. S. Kang, H. S. Lee et al., Association between Urinary Bisphenol A and Waist Circumference in Korean Adults, Toxicol Res, vol.30, issue.1, pp.39-44, 2014.

E. Labaronne, C. Pinteur, N. Vega, S. Pesenti, B. Julien et al., Low-dose pollutant mixture triggers metabolic disturbances in female mice leading to common and specific features as compared to a high-fat diet, J Nutr Biochem, vol.45, pp.83-93, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01603791

J. S. Lakind, M. Goodman, and D. Q. Naiman, Use of NHANES data to link chemical exposures to chronic diseases: a cautionary tale, PLoS One, vol.7, issue.12, 2012.

F. Leclerc, M. F. Dubois, and A. Aris, Maternal, placental and fetal exposure to bisphenol A in women with and without preeclampsia, Hypertens Pregnancy, vol.33, issue.3, pp.341-349, 2014.

M. R. Lee, J. H. Kim, Y. H. Choi, S. Bae, C. Park et al., Association of bisphenol A exposure with overweight in the elderly: a panel study, Environ Sci Pollut Res Int, vol.22, issue.12, pp.9370-9377, 2015.

C. Y. Lin, F. Y. Shen, G. W. Lian, K. L. Chien, F. C. Sung et al., Association between levels of serum bisphenol A, a potentially harmful chemical in plastic containers, and carotid artery intima-media thickness in adolescents and young adults, Atherosclerosis, issue.2, pp.657-63, 2015.

H. Y. Lin, I. C. Yu, R. S. Wang, Y. T. Chen, N. C. Liu et al., Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor, Hepatology, vol.47, issue.6, pp.1924-1959, 2008.

J. Liu, P. Yu, W. Qian, Y. Li, J. Zhao et al., Perinatal bisphenol A exposure and adult glucose homeostasis: identifying critical windows of exposure, PLoS One, vol.8, issue.5, p.64143, 2013.

Z. Mao, W. Xia, H. Chang, W. Huo, Y. Li et al., Paternal BPA exposure in early life alters Igf2 epigenetic status in sperm and induces pancreatic impairment in rat offspring, Toxicol Lett, vol.238, issue.3, pp.30-38, 2015.

K. J. Mather and R. B. Goldberg, Clinical use of adiponectin as a marker of metabolic dysregulation, Best Pract Res Clin Endocrinol Metab, vol.28, issue.1, pp.107-124, 2013.

M. , The role of estrogens in control of energy balance and glucose homeostasis, Endocr Rev, vol.34, issue.3, pp.309-338, 2013.

C. Menale, M. T. Piccolo, G. Cirillo, R. A. Calogero, A. Papparella et al., Bisphenol A effects on gene expression in adipocytes from children: association with metabolic disorders, J Mol Endocrinol, vol.54, issue.3, pp.289-303, 2015.

C. Menale, A. Grandone, C. Nicolucci, G. Cirillo, S. Crispi et al., Bisphenol A is associated with insulin resistance and modulates adiponectin and resistin gene expression in obese children, 2016.

J. Miyawaki, Perinatal and postnatal exposure to bisphenol a increases adipose tissue mass and serum cholesterol level in mice, Journal of Atherosclerosis and Thrombosis, vol.14, issue.5, pp.245-252, 2007.

H. S. Moghaddam, S. Samarghandian, and T. Farkhondeh, Effect of bisphenol A on blood glucose, lipid profile and oxidative stress indices in adult male mice, Toxicol Mech Methods, vol.25, issue.7, pp.507-520, 2015.

M. K. Moon, I. K. Jeong, J. Oh, T. Ahn, H. Y. Kim et al., Long-term oral exposure to bisphenol A induces glucose intolerance and insulin resistance, J Endocrinol, vol.226, issue.1, pp.35-42, 2015.

A. Nadal, P. Alonso-magdalena, S. Soriano, C. Ripoll, E. Fuentes et al., Role of estrogen receptors alpha, beta and GPER1/GPR30 in pancreatic beta-cells, Front Biosci (Landmark Ed), vol.1, pp.251-60, 2011.

A. Nadal, I. Quesada, E. Tudurí, R. Nogueiras, and P. Alonso-magdalena, Endocrinedisrupting chemicals and the regulation of energy balance, Nat Rev Endocrinol, vol.13, issue.9, pp.536-546, 2017.

G. Ning, Y. Bi, T. Wang, M. Xu, Y. Xu et al., Relationship of urinary bisphenol A concentration to risk for prevalent type 2 diabetes in Chinese adults: a cross-sectional analysis, Ann Intern Med, vol.155, issue.6, pp.368-74, 2011.

K. J. Oh, D. S. Lee, W. K. Kim, B. S. Han, S. C. Lee et al., Metabolic adaptation in obesity and type II diabetes: Myokines, adipokines and hepatokines, Int J Mol Sci, vol.18, 2017.

J. F. Ohlstein, A. L. Strong, J. A. Mclachlan, J. M. Gimble, M. E. Burow et al., Bisphenol A enhances adipogenic differentiation of human adipose stromal/stem cells, J Mol Endocrinol, vol.53, issue.3, pp.345-53, 2014.

A. Pedram, M. Razandi, B. Blumberg, and E. R. Levin, Membrane and nuclear estrogen receptor ? collaborate to suppress adipogenesis but not triglyceride content, FASEB J, vol.30, issue.1, pp.230-270, 2016.

. Pereira-fernandes, Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect, PLoS One, vol.8, issue.10, p.7748, 2013.

A. Pereira-fernandes, Toxicogenomics in the 3T3-L1 cell line, a new approach for screening of obesogenic compounds, Toxicol Sci, vol.140, issue.2, pp.352-63, 2014.

M. Ronn, L. Lind, J. Orberg, J. Kullberg, S. Soderberg et al., Bisphenol A is related to circulating levels of adiponectin, leptin and ghrelin, but not to fat mass or fat distribution in humans, Chemosphere, vol.112, pp.42-50, 2014.

E. Rosen, The transcriptional basis of adipocyte development, Prostaglandins Leukot Essent Fatty Acids, vol.73, issue.1, pp.31-35, 2005.

R. Dong and L. Q. , Adiponectin signaling and function in insulin target tissues, J Mol Cell Biol, vol.8, issue.2, pp.101-110, 2016.

B. S. Rubin, Perinatal BPA exposure alters body weight and composition in a dose specific and sex specific manner: The addition of peripubertal exposure exacerbates adverse effects in female mice, Reproductive Toxicology, vol.68, pp.130-144, 2017.

K. K. Ryan, A. M. Haller, J. E. Sorrell, S. C. Woods, R. J. Jandacek et al., Perinatal exposure t bisphenol-A and the development of metabolic syndrome in CD-1 mice, Endocrinology, vol.151, pp.2603-2612, 2010.

S. Savastano, G. Tarantino, D. 'esposito, V. Passaretti, F. Cabaro et al., Bisphenol-A plasma levels are related to inflammatory markers, visceral obesity and insulin-resistance: a cross-sectional study on adult male population, J Transl Med, vol.13, p.169, 2015.

R. A. Scott, T. Fall, D. Pasko, A. Barker, S. J. Sharp et al.,

H. Yaghootkar, . ;. Group, . Epic-interact-consortium, M. I. Mccarthy, R. K. Semple et al., Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity, Diabetes, vol.63, issue.12, pp.4378-87, 2014.

A. Shankar and S. Teppala, Relationship between urinary bisphenol A levels and diabetes mellitus, J Clin Endocrinol Metab, vol.96, issue.12, pp.3822-3828, 2011.

G. D. Shapiro, L. Dodds, T. E. Arbuckle, J. Ashley-martin, W. Fraser et al., Exposure to phthalates, bisphenol A and metals in pregnancy and the association with impaired glucose tolerance and gestational diabetes mellitus: The MIREC study, Environ Int, vol.83, pp.63-71, 2015.

M. K. Silver, O. Neill, M. S. , S. Mr, and S. K. Park, Urinary bisphenol A and type-2 diabetes in U.S. adults: data from NHANES, PLoS One, vol.6, p.10, 2003.

E. Somm, V. M. Schwitzgebel, A. Toulotte, C. R. Cederroth, C. Combescure et al., Perinatal exposure to bisphenol a alters early adipogenesis in the rat, Environ Health Perspect, vol.117, issue.10, pp.1549-55, 2009.

L. Song, W. Xia, Z. Zhou, Y. Li, Y. Lin et al., Lowlevel phenolic estrogen pollutants impair islet morphology and ?-cell function in isolated rat islets, J Endocrinol, vol.215, issue.2, pp.303-314, 2012.

Y. Song, R. Hauser, F. B. Hu, A. A. Franke, S. Liu et al., Urinary concentrations of bisphenol A and phthalate metabolites and weight change: a prospective investigation in US women, Int J Obes (Lond), vol.38, issue.12, pp.1532-1539, 2014.

S. Soriano, P. Alonso-magdalena, M. García-arévalo, A. Novials, S. J. Muhammed et al., Rapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor ?, PLoS One, vol.7, issue.2, p.31109, 2012.

Q. Sun, M. C. Cornelis, M. K. Townsend, D. K. Tobias, A. H. Eliassen et al., Association of urinary concentrations of bisphenol A and phthalate metabolites with risk of type 2 diabetes: a prospective investigation in the Nurses' Health Study (NHS) and NHSII cohorts, Environ Health Perspect, vol.122, issue.6, pp.616-639, 2014.

J. P. Tiano and F. Mauvais-jarvis, Importance of oestrogen receptors to preserve functional ?-cell mass in diabetes, Nat Rev Endocrinol, vol.8, issue.6, pp.342-51, 2012.

R. Valentino, D. 'esposito, V. Passaretti, F. Liotti, A. Cabaro et al., Bisphenol-A impairs insulin action and upregulates inflammatory pathways in human subcutaneous adipocytes and 3T3-L1 cells, PLoS One, vol.8, issue.12, p.82099, 2013.

J. C. Van-esterik, M. E. Dollé, M. H. Lamoree, S. P. Van-leeuwen, T. Hamers et al., Programming of metabolic effects in C57BL/6JxFVB mice by exposure to bisphenol A during gestation and lactation, Toxicology, vol.321, pp.40-52, 2014.

A. Veiga-lopez, J. Moeller, R. Sreedharan, K. Singer, C. Lumeng et al., Developmental programming: interaction between prenatal BPA exposure and postnatal adiposity on metabolic variables in female sheep, Am J Physiol Endocrinol Metab, vol.310, issue.3, pp.238-285, 2016.

V. Volberg, K. Harley, A. M. Calafat, V. Dave, J. Mcfadden et al., Maternal bisphenol a exposure during pregnancy and its association with, Environmental and Molecular Mutagenesis, vol.54, pp.621-628, 2013.

T. Wang, M. Li, B. Chen, M. Xu, Y. Xu et al., Urinary bisphenol A (BPA) concentration associates with obesity and insulin resistance, J Clin Endocrinol Metab, vol.97, issue.2, pp.223-230, 2012.

J. Wang, B. Sun, M. Hou, X. Pan, and X. Li, The environmental obesogen bisphenol A promotes adipogenesis by increasing the amount of 11?-hydroxysteroid dehydrogenase type 1 in the adipose tissue of children, Int J Obes (Lond), vol.37, issue.7, pp.999-1005, 2013.

J. Wei, Y. Lin, Y. Li, C. Ying, J. Chen et al., Perinatal exposure to bisphenol A at reference dose predisposes offspring to metabolic syndrome in adult rats on a high-fat diet, Endocrinology, vol.152, issue.8, pp.3049-61, 2011.

R. Whitehead, H. Guan, E. Arany, M. Cernea, and Y. K. , Prenatal exposure to bisphenol A alters mouse fetal pancreatic morphology and islet composition, Horm Mol Biol Clin Investig, vol.25, issue.3, pp.171-180, 2016.

Q. Xiong, X. Liu, Y. Shen, P. Yu, S. Chen et al., Elevated serum bisphenol a level in patients with dilated cardiomyopathy, Int J Environ Res Public Health, vol.12, issue.5, pp.5329-5366, 2015.

M. Yang, M. Chen, J. Wang, M. Xu, J. Sun et al., Bisphenol A promotes adiposity and inflammation in a nonmonotonic dose-response way in five-week old male and female C57BL/6J mice fed a lowcalorie diet, Endocrinology, vol.157, issue.6, pp.2333-2378, 2016.

H. Zhang, Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat, J Lipid Res, vol.54, issue.2, pp.345-57, 2013.