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Journal articles
New transcriptomic tools to understand testis development and functions
Abstract : The testis plays a central role in the male reproductive system - secreting several hormones including male steroids and producing male gametes. A complex and coordinated molecular program is required for the proper differentiation of testicular cell types and maintenance of their functions in adulthood. The testicular transcriptome displays the highest levels of complexity and specificity across all tissues in a wide range of species. Many studies have used high-throughput sequencing technologies to define the molecular dynamics and regulatory networks in the testis as well as to identify novel genes or gene isoforms expressed in this organ. This review intends to highlight the complementarity of these transcriptomic studies and to show how the use of different sequencing protocols contribute to improve our global understanding of testicular biology.
Cited literature [194 references]
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01864339
Contributor : Laurent Jonchère Connect in order to contact the contributor
Submitted on : Thursday, August 30, 2018 - 1:24:16 PM
Last modification on : Wednesday, October 20, 2021 - 3:19:22 AM
Contributor : Laurent Jonchère Connect in order to contact the contributor
Submitted on : Thursday, August 30, 2018 - 1:24:16 PM
Last modification on : Wednesday, October 20, 2021 - 3:19:22 AM
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Lecluze et al_New transcriptom...
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