, 144 g, 1.5 mmol) affords 48 in 75% (0.152 g) yield as a colourless oil. 1 H NMR (400 MHz, vol.3, p.5
, 182 g, 1 mmol) and 3,5-dimethylisoxazole (0.144 g, 1.5 mmol) affords 49 in 91% (0.180 g) yield as a white solid
, Hz, 1H), 7.66 (td, J = 7.9, 1.4 Hz, 1H), vol.7
, g, 1 mmol) and imidazo[1,2-a]pyridine (0.177 g, 1.5 mmol) affords 50 in 94% (0.206 g) yield as a yellow solid
, g, 1 mmol) and imidazo[1,2-a]pyridine (0.177 g, 1.5 mmol) affords 51 in 96% (0.226 g) yield as a yellow solid
, , vol.6
, 187 g, 1 mmol) and imidazo[1,2-a]pyridine (0.177 g, 1.5 mmol) affords 52 in 93% (0.208 g) yield as a white solid, vol.1
,
, Hz, 2H), 7.17 (t, J = 8.0 Hz, 1H), vol.7
, 182 g, 1 mmol) and imidazo[1,2-a]pyridine (0.177 g, 1.5 mmol) affords 53 in 92% (0.201 g) yield as a white solid
, acetone-d6): ? 8.35 (d, J = 6.8 Hz, 1H), 7.99 (dd, J = 7.8, 0.8 Hz, 1H)
, g, 1.5 mmol) affords 54 in 94% (0.230 g) yield as a yellow solid: mp 146-148 °C. 1 H NMR (400 MHz, CDCl3): ? 9, g, 1 mmol) and imidazo, vol.1
, Bromobenzonitrile (0.182 g, 1 mmol) and imidazo, vol.1
, mmol) affords 55 in 95% (0.209 g) yield as a white solid, p.159
, g, 1 mmol) and imidazo[1,2-b]pyridazine (0.178 g, 1.5 mmol) affords 56 in 96% (0.230 g) yield as a yellow solid
, g, 1 mmol) and imidazo[1,2-b]pyridazine (0.178 g, 1.5 mmol) affords 57 in 93% (0.213 g) yield as a yellow solid, Hz, 1H), 8.52 (d, J = 8.9 Hz, 2H), 8.42 (s, 1H), 8.33 (d, J = 8.9 Hz, 2H), 8.15 (dd, J = 8.2, 1.6 Hz, 1H), vol.7
, g, 1 mmol) and imidazo[1,2-b]pyridazine (0.178 g, 1.5 mmol) affords 58 in 90% (0.202 g) yield as a yellow solid
, Bromobenzonitrile (0.182 g, 1 mmol) and imidazo, vol.1
, mmol) affords 59 in 96% (0.211 g) yield as a yellow solid: mp 214216 °C. 1 H NMR (400 MHz, CDCl3): ? 8.47
, , vol.7
, g, 1 mmol) and imidazo[1,2-b]pyridazine (0.178 g, 1.5 mmol) affords 60 in 88% (0.172 g) yield as a yellow solid: mp 112-114 °C. 1 H NMR (400 MHz, CDCl3): ? 9
, 10 (s, 1H), 8.02 (dd, Hz, 1H), 8.46-8.36 (m, 2H), vol.8
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