P. Ponikowski, A. A. Voors, S. D. Anker, H. Bueno, J. Cleland et al., Authors/Task Force Members, Document Reviewers. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC, Eur Heart J, vol.37, pp.2129-2200, 2016.

A. P. Maggioni, U. Dahlström, G. Filippatos, O. Chioncel, C. Leiro et al., EURObservational Research Programme: regional differences and 1-year follow-up results of the Heart Failure Pilot Survey (ESC-HF Pilot), Eur J Heart Fail, vol.15, pp.808-817, 2013.

D. Logeart, R. Isnard, M. Resche-rigon, M. Seronde, P. De-groote et al., Heart Failure of the French Society of Cardiology. Current aspects of the spectrum of acute heart failure syndromes in a real-life setting: the OFICA study, Eur J Heart Fail, vol.15, pp.465-476, 2013.

P. De-groote, R. Isnard, P. Clerson, G. Jondeau, M. Galinier et al., Improvement in the management of chronic heart failure since the publication of the updated guidelines of the European Society of Cardiology. The Impact-Reco Programme, Eur J Heart Fail, vol.11, pp.85-91, 2009.

S. Ghio, A. Gavazzi, C. Campana, C. Inserra, C. Klersy et al., Independent and additive prognostic value of right ventricular systolic function and pulmonary artery pressure in patients with chronic heart failure, J Am Coll Cardiol, vol.37, pp.183-188, 2001.

T. Damy, K. M. Goode, A. Kallvikbacka-bennett, C. Lewinter, J. Hobkirk et al., Determinants and prognostic value of pulmonary arterial pressure in patients with chronic heart failure, Eur Heart J, vol.31, pp.2280-2290, 2010.

C. Lam, V. L. Roger, R. J. Rodeheffer, B. A. Borlaug, F. T. Enders et al., Pulmonary hypertension in heart failure with preserved ejection fraction: a community-based study, J Am Coll Cardiol, vol.53, pp.1119-1126, 2009.

A. M. Shah, S. J. Shah, I. S. Anand, N. K. Sweitzer, E. O'meara et al., TOPCAT Investigators. Cardiac structure and function in heart failure with preserved ejection fraction: baseline findings from the echocardiographic study of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist trial, Circ Heart Fail, vol.7, pp.104-115, 2014.

B. A. Maron, E. Hess, T. M. Maddox, A. R. Opotowsky, R. J. Tedford et al.,

G. , Association of borderline pulmonary hypertension with mortality and hospitalization in a large patient cohort: Insights from the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program, Circulation, vol.133, pp.1240-1248, 2016.

P. De-groote, M. Fertin, C. Goéminne, G. Petyt, S. Peyrot et al., Right ventricular systolic function for risk stratification in patients with stable left ventricular systolic dysfunction: comparison of radionuclide angiography to echoDoppler parameters, Eur Heart J, vol.33, pp.2672-2679, 2012.

S. Breitling, K. Ravindran, N. M. Goldenberg, and W. M. Kuebler, The pathophysiology of pulmonary hypertension in left heart disease, Am J Physiol Lung Cell Mol Physiol, vol.309, pp.924-941, 2015.

J. B. West and O. Mathieu-costello, Vulnerability of pulmonary capillaries in heart disease, Circulation, vol.92, pp.622-631, 1995.

J. F. Delgado, E. Conde, V. Sánchez, F. López-ríos, M. A. Gómez-sánchez et al., Pulmonary vascular remodeling in pulmonary hypertension due to chronic heart failure, Eur J Heart Fail, vol.7, pp.1011-1016, 2005.

Y. S. Lee, Electron microscopic studies on the alveolar-capillary barrier in the patients of chronic pulmonary edema, Jpn Circ J, vol.43, pp.945-954, 1979.

S. Ghio, G. Crimi, S. Pica, P. L. Temporelli, M. Boffini et al., Persistent abnormalities in pulmonary arterial compliance after heart transplantation in patients with combined post-capillary and precapillary pulmonary hypertension, PLoS One, vol.12, p.188383, 2017.

, Pulmonary hypertension in chronic heart failure

T. Damy, C. Viallet, O. Lairez, G. Deswarte, A. Paulino et al., Comparison of four right ventricular systolic echocardiographic parameters to predict adverse outcomes in chronic heart failure, Eur J Heart Fail, vol.11, pp.818-824, 2009.
URL : https://hal.archives-ouvertes.fr/inserm-00414783

S. F. Mohammed, I. Hussain, O. F. Abouezzeddine, H. Takahama, S. H. Kwon et al., Right ventricular function in heart failure with preserved ejection fraction: a community-based study, Circulation, vol.130, pp.2310-2320, 2014.

S. Ghio, P. L. Temporelli, C. Klersy, A. Simioniuc, B. Girardi et al., Prognostic relevance of a non-invasive evaluation of right ventricular function and pulmonary artery pressure in patients with chronic heart failure, Eur J Heart Fail, vol.15, pp.408-414, 2013.

S. Frea, S. Pidello, V. Bovolo, C. Iacovino, E. Franco et al., Prognostic incremental role of right ventricular function in acute decompensation of advanced chronic heart failure, Eur J Heart Fail, vol.18, pp.564-572, 2016.

M. R. Mehra, C. E. Canter, M. M. Hannan, M. J. Semigran, P. A. Uber et al., International Society for Heart Lung Transplantation (ISHLT) Infectious Diseases Council, International Society for Heart Lung Transplantation (ISHLT) Pediatric Transplantation Council, International Society for Heart Lung Transplantation (ISHLT) Heart Failure and Transplantation Council. The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: a 10-year update, J Heart Lung Transplant, vol.35, pp.1-23, 2016.

N. Galiè, M. M. Hoeper, M. Humbert, A. Torbicki, J. Vachiery et al., Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT), Eur Heart J, vol.30, pp.2493-2537, 2009.

W. L. Miller, D. E. Grill, and B. A. Borlaug, Clinical features, hemodynamics, and outcomes of pulmonary hypertension due to chronic heart failure with reduced ejection fraction: pulmonary hypertension and heart failure, JACC Heart Fail, vol.1, pp.290-299, 2013.

E. Tampakakis, P. J. Leary, V. N. Selby, D. Marco, T. Cappola et al., The diastolic pulmonary gradient does not predict survival in patients with pulmonary hypertension due to left heart disease, JACC Heart Fail, vol.3, pp.9-16, 2015.

R. J. Tedford, C. A. Beaty, S. C. Mathai, T. M. Kolb, R. Damico et al., Prognostic value of the pre-transplant diastolic pulmonary artery pressure-to-pulmonary capillary wedge pressure gradient in cardiac transplant recipients with pulmonary hypertension, J Heart Lung Transplant, vol.33, pp.289-297, 2014.

C. Gerges, M. Gerges, M. B. Lang, Y. Zhang, J. Jakowitsch et al., Diastolic pulmonary vascular pressure gradient: a predictor of prognosis in 'out-of-proportion' pulmonary hypertension, Chest, vol.143, pp.758-766, 2013.

N. Galiè, M. Humbert, J. Vachiery, S. Gibbs, I. Lang et al., ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the, ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT), vol.37, pp.67-119, 2015.

D. Aronson, A. Eitan, R. Dragu, and A. J. Burger, Relationship between reactive pulmonary hypertension and mortality in patients with acute decompensated heart failure, Circ Heart Fail, vol.4, pp.644-650, 2011.

P. Pellegrini, A. Rossi, M. Pasotti, C. Raineri, M. Cicoira et al., Prognostic relevance of pulmonary arterial compliance in patients with chronic heart failure, Chest, vol.145, pp.1064-1070, 2014.

N. Al-naamani, I. R. Preston, J. K. Paulus, N. S. Hill, and K. E. Roberts, Pulmonary arterial capacitance is an important predictor of mortality in heart failure with a preserved ejection fraction, JACC Heart Fail, vol.3, pp.467-474, 2015.

R. Dragu, S. Rispler, M. Habib, H. Sholy, H. Hammerman et al., Pulmonary arterial capacitance in patients with heart failure and reactive pulmonary hypertension, Eur J Heart Fail, vol.17, pp.74-80, 2015.

A. Vonk-noordegraaf, B. E. Westerhof, and N. Westerhof, The relationship between the right ventricle and its load in pulmonary hypertension, J Am Coll Cardiol, vol.69, pp.236-243, 2017.

F. Goodale, G. Sanchez, A. L. Friedlich, J. G. Scannell, and G. S. Myers, Correlation of pulmonary arteriolar resistance with pulmonary vascular changes in patients with mitral stenosis before and after valvulotomy, N Engl J Med, vol.252, pp.979-983, 1955.

S. C. Masri, R. J. Tedford, M. M. Colvin, P. J. Leary, and R. Cogswell, Pulmonary arterial compliance improves rapidly after left ventricular assist device implantation

, ASAIO J, vol.63, pp.139-143, 2017.

J. W. Ha, N. Chung, Y. Jang, W. C. Kang, S. M. Kang et al., Is the left atrial v. wave the determinant of peak pulmonary artery pressure in patients with pure mitral stenosis?, Am J Cardiol, vol.85, pp.986-991, 2000.

T. Sugimoto, F. Bandera, G. Generati, E. Alfonzetti, C. Bussadori et al., Left atrial function dynamics during exercise in heart failure: pathophysiological implications on the right heart and exercise ventilation inefficiency, JACC Cardiovasc Imaging, vol.10, pp.1253-1264, 2017.

D. Aronson, W. Darawsha, A. Atamna, M. Kaplan, B. F. Makhoul et al., Pulmonary hypertension, right ventricular function, and clinical outcome in acute decompensated heart failure, J Card Fail, vol.19, pp.665-671, 2013.

K. K. Khush, G. Tasissa, J. Butler, D. Mcglothlin, D. Marco et al., ESCAPE Investigators. Effect of pulmonary hypertension on clinical outcomes in advanced heart failure: analysis of the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) database, Am Heart J, vol.157, pp.1026-1034, 2009.

M. Palazzini, F. Dardi, A. Manes, M. L. Bacchi-reggiani, E. Gotti et al., Pulmonary hypertension due to left heart disease: analysis of survival according to the haemodynamic classification of the 2015 ESC/ERS guidelines and insights for future changes, Eur J Heart Fail, vol.20, pp.248-255, 2018.

P. B. Adamson, W. T. Abraham, R. C. Bourge, M. R. Costanzo, A. Hasan et al., Wireless pulmonary artery pressure monitoring guides management to reduce decompensation in heart failure with preserved ejection fraction, Circ Heart Fail, vol.7, pp.935-944, 2014.

F. Bursi, S. M. Mcnallan, M. M. Redfield, V. T. Nkomo, C. Lam et al., Pulmonary pressures and death in heart failure: a community study, J Am Coll Cardiol, vol.59, pp.222-231, 2012.

C. F. Opitz, M. M. Hoeper, J. Gibbs, H. Kaemmerer, J. Pepke-zaba et al.,

E. Berthelot,

. Cd, G. Staehler, L. Bruch, D. Huscher, D. Pittrow et al., Pre-capillary, combined, and post-capillary pulmonary hypertension: a pathophysiological continuum, J Am Coll Cardiol, vol.68, pp.368-378, 2016.

P. De-groote, E. Asri, C. Fertin, M. Goéminne, C. Vincentelli et al., Sildenafil in heart transplant candidates with pulmonary hypertension, Arch Cardiovasc Dis, vol.108, pp.375-384, 2015.

M. M. Redfield, H. H. Chen, B. A. Borlaug, M. J. Semigran, K. L. Lee et al., Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial, JAMA, vol.309, pp.1268-1277, 2013.

J. Bermejo, R. Yotti, R. García-orta, P. L. Sánchez-fernández, M. Castaño et al., Sildenafil for Improving Outcomes after VAlvular Correction (SIOVAC) investigators. Sildenafil for improving outcomes in patients with corrected valvular heart disease and persistent pulmonary hypertension: a multicenter, double-blind, randomized clinical trial, Eur Heart J, vol.39, pp.1255-1264, 2018.

T. Damy, J. Hobkirk, M. Walters, A. Ciobanu, A. S. Rigby et al., Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure, J Cardiovasc Pharmacol, vol.66, pp.229-238, 2015.

J. L. Vachiéry, M. Delcroix, H. Al-hiti, M. Efficace, M. Hutyra et al., Macitentan in pulmonary hypertension due to left ventricular dysfunction, Eur Respir J, vol.51, p.1701886, 2018.

D. Zimpfer, P. Zrunek, W. Roethy, M. Czerny, H. Schima et al., Left ventricular assist devices decrease fixed pulmonary hypertension in cardiac transplant candidates, J Thorac Cardiovasc Surg, vol.133, pp.689-695, 2007.

R. John, K. Liao, F. Kamdar, P. Eckman, A. Boyle et al., Effects on pre-and posttransplant pulmonary hemodynamics in patients with continuous-flow left ventricular assist devices, J Thorac Cardiovasc Surg, vol.140, pp.447-452, 2010.

S. Ghio, G. Crimi, P. L. Temporelli, E. Traversi, L. Rovere et al., Haemodynamic effects of an acute vasodilator challenge in heart failure patients with reduced ejection fraction and different forms of postcapillary pulmonar hypertension, Eur J Heart Fail, vol.20, pp.725-734, 2018.

M. Amsallem, J. M. Sternbach, S. Adigopula, Y. Kobayashi, T. A. Vu et al., Addressing the controversy of estimating pulmonary arterial pressure by echocardiography, J Am Soc Echocardiogr, vol.29, pp.93-102, 2016.

S. Janda, N. Shahidi, K. Gin, and J. Swiston, Diagnostic accuracy of echocardiography for pulmonary hypertension: a systematic review and meta-analysis, Heart Br Card Soc, vol.97, pp.612-622, 2011.

E. Berthelot, D. Montani, V. Algalarrondo, C. Dreyfuss, R. Rifai et al., A clinical and echocardiographic score to identify pulmonary hypertension due to HFpEF, J Card Fail, vol.23, pp.29-35, 2017.

S. Ley, C. Fink, F. Risse, N. Ehlken, C. Fischer et al., Magnetic resonance imaging to assess the effect of exercise training on pulmonary perfusion and blood flow in patients with pulmonary hypertension, Eur Radiol, vol.23, pp.324-331, 2013.

M. Pienn, G. Kovacs, M. Tscherner, A. Avian, T. R. Johnson et al., Non-invasive determination of pulmonary hypertension with dynamic contrast-enhanced computed tomography: a pilot study, Eur Radiol, vol.24, pp.668-676, 2014.

F. Rengier, S. Wörz, C. Melzig, S. Ley, C. Fink et al., Automated 3D volumetry of the pulmonary arteries based on magnetic resonance angiography has potential for predicting pulmonary hypertension, PLoS One, vol.11, p.162516, 2016.

D. M. Kaye, G. Hasenfuß, P. Neuzil, M. C. Post, R. Doughty et al., One-year outcomes after transcatheter insertion of an interatrial shunt device for the management of heart failure with preserved ejection fraction, Circ Heart Fail, vol.9, p.3662, 2016.

D. Burkhoff, M. S. Maurer, S. M. Joseph, J. G. Rogers, E. Y. Birati et al., Left atrial decompression pump for severe heart failure with preserved ejection fraction: theoretical and clinical considerations, JACC Heart Fail, vol.3, pp.275-282, 2015.

G. Laurent, J. C. Eicher, A. Mathe, G. Bertaux, O. Barthez et al., Permanent left atrial pacing therapy may improve symptoms in heart failure patients with preserved ejection fraction and atrial dyssynchrony: a pilot study prior to a national clinical research programme, Eur J Heart Fail, vol.15, pp.85-93, 2013.

, Pulmonary hypertension in chronic heart failure