Far upstream element binding protein 1: a commander of transcription, translation and beyond, Oncogene, vol.32, pp.2907-2916, 2013. ,
A far upstream element stimulates c-myc expression in undifferentiated leukemia cells, J Biol Chem, vol.265, pp.18538-18545, 1990. ,
A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNAbinding motif, Genes Dev, vol.8, pp.465-480, 1994. ,
How the c-myc Promoter Works and Why It Sometimes Does Not, JNCI Monogr, pp.41-43, 2008. ,
JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress, EMBO J, vol.30, pp.846-858, 2011. ,
Overexpression of far upstream element binding proteins: A mechanism regulating proliferation and migration in liver cancer cells, Hepatology, vol.50, pp.1130-1139, 2009. ,
Overexpression of far upstream element (FUSE) binding protein (FBP)-interacting repressor (FIR) supports growth of hepatocellular carcinoma, Hepatology, vol.60, pp.1241-1250, 2014. ,
Overexpression of the far upstream element binding protein 1 in hepatocellular carcinoma is required for tumor growth, Hepatology, vol.50, pp.1121-1129, 2009. ,
Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity: FUBP1 expression in human gliomas, Neuropathol Appl Neurobiol, vol.40, pp.205-216, 2014. ,
Upregulation of Far Upstream Element-Binding Protein 1 (FUBP1) Promotes Tumor Proliferation and Tumorigenesis of Clear Cell Renal Cell Carcinoma, PLOS ONE, vol.12, 2017. ,
Pyrazolo[1,5a]pyrimidines as a new class of FUSE binding protein 1 (FUBP1) inhibitors, Bioorg Med Chem, vol.24, pp.5717-5729, 2016. ,
Transient excess of MYC activity can elicit genomic instability and tumorigenesis, Proc Natl Acad Sci U S A, vol.96, pp.3940-3944, 1999. ,
, The FBP Interacting Repressor Targets TFIIH to Inhibit Activated Transcription. Mol Cell, vol.5, issue.00, pp.80428-80429, 2000.
The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression, EMBO J, vol.25, pp.2119-2130, 2006. ,
An Essential Role of Alternative Splicing of c-myc Suppressor FUSE-Binding Protein-Interacting Repressor in Carcinogenesis, Cancer Res, vol.66, pp.1409-1417, 2006. ,
Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition, EMBO J, vol.27, pp.277-289, 2008. ,
TFIIH Operates through an Expanded Proximal Promoter To Fine-Tune c-myc Expression, Mol Cell Biol, vol.25, pp.147-61, 2005. ,
The role of stathmin in the regulation of the cell cycle, J Cell Biochem, vol.93, pp.242-250, 2004. ,
Role of stathmin in the regulation of the mitotic spindle: potential applications in cancer therapy, Mt Sinai J Med N Y, vol.69, pp.299-304, 2002. ,
Stathmin activity influences sarcoma cell shape, motility, and metastatic potential, Mol Biol Cell, vol.19, pp.2003-2013, 2008. ,
Global gene expression analysis reveals specific patterns of cell junctions in non-small cell lung cancer subtypes, Lung Cancer Amst Neth, vol.63, pp.32-38, 2009. ,
Hox genes in vertebrate development, Cell, vol.78, pp.191-201, 1994. ,
The role of HOX homeobox genes in normal and leukemic hematopoiesis, Stem Cells Dayt Ohio, vol.14, pp.281-291, 1996. ,
Stem cell factor and hematopoiesis, Blood, vol.90, pp.1345-1364, 1997. ,
Kit as a human oncogenic tyrosine kinase, Cell Mol Life Sci CMLS, vol.61, pp.2924-2931, 2004. ,
negative regulator of the cell cycle, Proc Soc Exp Biol Med Soc Exp Biol Med N Y N, vol.213, pp.138-149, 1996. ,
The role of the cyclin-dependent kinase inhibitor p21 in apoptosis, Mol Cancer Ther, vol.1, pp.639-649, 2002. ,
differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation, J Cell Sci, vol.121, pp.3271-3282, 2008. ,
Fuse binding protein antagonizes the transcription activity of tumor suppressor protein p53, BMC Cancer, vol.14, 2014. ,
FUSE Binding Protein 1 Facilitates Persistent Hepatitis C Virus Replication in Hepatoma Cells by Regulating Tumor Suppressor p53, J Virol, vol.89, pp.7905-7921, 2015. ,
Adenovirus 5 E1A-mediated suppression of p53 via FUBP1, J Virol, 2018. ,
Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degradation factor-1], AUF2, tristetraprolin, HuR (Hu antigen R) or FBP1 (far-upstream-sequence-elementbinding protein 1), Biochem J, vol.377, pp.629-639, 2004. ,
The FUSE Binding Protein Is a Cellular Factor Required for Efficient Replication of Hepatitis C Virus, J Virol, vol.82, pp.5761-5773, 2008. ,
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators, Proc Natl Acad Sci U S A, vol.83, pp.1670-1674, 1986. ,
AU-rich element-mediated translational control: complexity and multiple activities of trans-activating factors, Biochem Soc Trans, vol.30, pp.952-958, 2002. ,
The role of KSRP in mRNA decay and microRNA precursor maturation, Wiley Interdiscip Rev RNA, vol.1, pp.230-239, 2010. ,
The Splicing Factor FUBP1 Is Required for the Efficient Splicing of Oncogene MDM2 Pre-mRNA, J Biol Chem, vol.289, pp.17350-17364, 2014. ,
FUBP1: a new protagonist in splicing regulation of the DMD gene, Nucleic Acids Res, vol.43, pp.2378-2389, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01279092
Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation, J Am Soc Nephrol, 2016. ,
Identification of two proteins that bind to a pyrimidine-rich sequence in the 3'-untranslated region of GAP43 mRNA, Nucleic Acids Res, vol.25, pp.1281-1288, 1997. ,
Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation, Oncogene, vol.30, pp.77-86, 2011. ,
Nucleophosmin: from structure and function to disease development, BMC Mol Biol, vol.17, 2016. ,
The survival motor neuron protein interacts with the transactivator FUSE binding protein from human fetal brain, FEBS Lett, vol.470, pp.207-210, 2000. ,
Far upstream element binding protein 1 activates translation of p27Kip1 mRNA through its internal ribosomal entry site, Int J Biochem Cell Biol, vol.43, pp.1641-1648, 2011. ,
Far upstream element binding protein 1 binds the internal ribosomal entry site of enterovirus 71 and enhances viral translation and viral growth, Nucleic Acids Res, vol.39, pp.9633-9648, 2011. ,
Kaempferol inhibits enterovirus 71 replication and internal ribosome entry site (IRES) activity through FUBP and HNRP proteins, Food Chem, vol.128, pp.312-322, 2011. ,
Additive Promotion of Viral Internal Ribosome Entry Site-Mediated Translation by Far Upstream Element-Binding Protein 1 and an Enterovirus 71-Induced Cleavage Product, PLoS Pathog, vol.12, 2016. ,
Far upstream element binding protein 2 interacts with enterovirus 71 internal ribosomal entry site and negatively regulates viral translation, Nucleic Acids Res, vol.37, pp.47-59, 2009. ,
A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer, Genes Dev, vol.11, pp.1023-1036, 1997. ,
Modulation of P-Element Pre-mRNA Splicing by a Direct Interaction between PSI and U1 snRNP 70K Protein, Mol Cell, vol.8, pp.311-313, 2001. ,
Large-Scale Proteomic Analysis of the Human Spliceosome, Genome Res, vol.12, pp.1231-1245, 2002. ,
,
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing, Nat Genet, vol.40, pp.1413-1415, 2008. ,
Far upstream element-binding protein 1 and RNA secondary structure both mediate second-step splicing repression, Proc Natl Acad Sci, vol.110, pp.2687-2695, 2013. ,
Spliceosome Structure and Function, Cold Spring Harb Perspect Biol, vol.3, 2011. ,
Mechanistic studies of a small-molecule modulator of SMN2 splicing, Proc Natl Acad Sci U S A, vol.115, pp.4604-4612, 2018. ,
Functions of the MDM2 oncoprotein, Cell Mol Life Sci CMLS, vol.55, pp.96-107, 1999. ,
The muscular dystrophies, Lancet Lond Engl, vol.359, pp.7815-7822, 2002. ,
In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors, Genome Res, vol.28, pp.699-713, 2018. ,
Far Upstream Element-Binding Protein 1 Regulates LSD1 Alternative Splicing to Promote Terminal Differentiation of Neural Progenitors, Stem Cell Rep, 2018. ,
The epidemiology of glioma in adults: a "state of the science, review. Neuro-Oncol, vol.16, pp.896-913, 2014. ,
,
Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene, Clin Cancer Res Off J Am Assoc Cancer Res, vol.11, pp.1119-1128, 2005. ,
CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas, Acta Neuropathol (Berl), vol.123, pp.853-860, 2012. ,
Loss of CIC and FUBP1 expressions are potential markers of shorter time to recurrence in oligodendroglial tumors, Mod Pathol Off J U S Can Acad Pathol Inc, vol.27, pp.332-342, 2014. ,
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas, N Engl J Med, vol.372, pp.2481-2498, 2015. ,
Mutational landscape and clonal architecture in grade II and III gliomas, Nat Genet, vol.47, pp.458-468, 2015. ,
Genetic and epigenetic stability of oligodendrogliomas at recurrence, Acta Neuropathol Commun, vol.5, 2017. ,
Amplification of c-myc in hepatocellular carcinoma: correlation with clinicopathologic features, proliferative activity and p53 overexpression, Oncology, vol.57, pp.157-163, 1999. ,
,
Hepatocellular carcinoma: epidemiology and molecular carcinogenesis, Gastroenterology, vol.132, pp.2557-2576, 2007. ,
,
Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis, Cancer Res, vol.53, pp.1719-1723, 1993. ,
Novel recurrent genetic imbalances in human hepatocellular carcinoma cell lines identified by comparative genomic hybridization, Hepatol Baltim Md, vol.29, pp.1208-1214, 1999. ,
,
Etiology-dependent molecular mechanisms in human hepatocarcinogenesis, Hepatol Baltim Md, vol.47, pp.511-520, 2008. ,
2-D DIGE profiling of hepatocellular carcinoma tissues identified isoforms of far upstream binding protein (FUBP) as novel candidates in liver carcinogenesis, Proteomics, vol.8, pp.5086-5096, 2008. ,
,
Expression of far upstream element-binding protein 1 correlates with c-Myc expression in sacral chordomas and is associated with tumor progression and poor prognosis, Biochem Biophys Res Commun, vol.491, pp.1047-1054, 2017. ,
Fuse-binding protein 1 is a target of the EZH2 inhibitor GSK343, in osteosarcoma cells, Int J Oncol, vol.49, pp.623-628, 2016. ,
Overexpression of the stathmin gene in a subset of human breast cancer, Br J Cancer, vol.78, pp.701-709, 1998. ,
Concomitant expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non-small cell lung cancer (NSCLC) cells, J Pathol, vol.237, pp.390-401, 2015. ,
Meta-analysis of 8q24 for seven cancers reveals a locus between NOV and ENPP2 associated with cancer development, BMC Med Genet, vol.12, p.156, 2011. ,
Genomic aberrations in squamous cell lung carcinoma related to lymph node or distant metastasis, Lung Cancer Amst Neth, vol.66, pp.372-378, 2009. ,
Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological graderesults of an explorative CGH meta-analysis, Br J Cancer, vol.92, pp.935-941, 2005. ,
) c-myc suppressor FBP-interacting repressor for cancer diagnosis and therapy, Front Biosci Landmark Ed, vol.14, pp.3401-3408, 2009. ,
Hepatitis C virus infection is associated with the development of hepatocellular carcinoma, Proc Natl Acad Sci, vol.87, pp.6547-6549, 1990. ,
Hepatitis C viral RNA: challenges and promises, Cell Mol Life Sci CMLS, vol.58, pp.1276-1295, 2001. ,
Delayed Mesoderm and Erythroid Differentiation of Murine Embryonic Stem Cells in the Absence of the Transcriptional Regulator FUBP1, Stem Cells Int, vol.2017, pp.1-12, 2017. ,
) c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation, Genes Dev, vol.18, pp.2747-2763, 2004. ,
Hematopoietic Stem Cell Differentiation Regulated by a Single Ubiquitin Ligase: Substrate Complex, Nat Immunol, vol.11, pp.207-215, 2010. ,
The proto-oncogene c-myc in hematopoietic development and leukemogenesis, Oncogene, vol.21, pp.3414-3421, 2002. ,
Enforced expression of the c-myc oncogene inhibits cell differentiation by precluding entry into a distinct predifferentiation state in G0/G1, Mol Cell Biol, vol.8, pp.1614-1624, 1988. ,
Role of c-myc in myeloid differentiation, growth arrest and apoptosis, Curr Top Microbiol Immunol, vol.211, pp.17-27, 1996. ,
Stem cell gene expression programs influence clinical outcome in human leukemia, Nat Med, vol.17, pp.1086-1093, 2011. ,
Myc Roles in Hematopoiesis and Leukemia, Genes Cancer, 2010. ,
Normal and Oncogenic Forms of the Receptor Tyrosine Kinase Kit, STEM CELLS, vol.23, pp.16-43, 2005. ,
Constitutive Kit activity triggers B-cell acute lymphoblastic leukemia-like disease in mice, Exp Hematol, vol.45, pp.45-55, 2017. ,
Mutations driving CLL and their evolution in progression and relapse, Nature, vol.526, pp.525-530, 2015. ,
,
Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes, Oncotarget Sep, vol.27, pp.64071-64088, 2016. ,
Mantle cell lymphoma-variant Richter syndrome: Detailed molecular-cytogenetic and backtracking analysis reveals slow evolution of a pre-MCL clone in parallel with CLL over several years: Mantle cell lymphoma-variant Richter syndrome, Int J Cancer, vol.139, pp.2252-2260, 2016. ,
,
NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter, J Med Chem, vol.47, pp.4851-4857, 2004. ,
EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers, PloS One, vol.8, 2013. ,
Enhancer of zeste homolog 2 silencing inhibits tumor growth and lung metastasis in osteosarcoma, Sci Rep, vol.5, 2015. ,
The proteome profile of the human osteosarcoma U2OS cell line, Cancer Genomics Proteomics, vol.5, pp.63-78, 2008. ,
The polycomb group protein EZH2 is involved in progression of prostate cancer, Nature, vol.419, pp.624-629, 2002. ,
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells, Proc Natl Acad Sci U S A, vol.100, pp.11606-11611, 2003. ,
Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE, Biochem Pharmacol, vol.146, pp.53-62, 2017. ,
Exploring genomic alteration in pediatric cancer using ProteinPaint, Nat Genet, vol.48, pp.4-6, 2016. ,
DOI : 10.1038/ng.3466
URL : http://europepmc.org/articles/pmc4892362?pdf=render
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity, Nature, vol.483, pp.603-607, 2012. ,
SNP array analysis reveals novel genomic abnormalities including copy neutral loss of heterozygosity in anaplastic oligodendrogliomas, PloS One, vol.7, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00911465
, Molecular background of oligodendroglioma: 1p/19q, vol.4, pp.287-294, 2015.
DOI : 10.2217/cns.15.32
Tumor-specific mutations in low-frequency genes affect their functional properties, J Neurooncol, vol.122, pp.461-470, 2015. ,
DOI : 10.1007/s11060-015-1741-1
URL : https://link.springer.com/content/pdf/10.1007%2Fs11060-015-1741-1.pdf
EZH2-, CHD4-, and IDH-linked epigenetic perturbation and its association with survival in glioma patients, J Mol Cell Biol, 2017. ,
DOI : 10.1093/jmcb/mjx056
Prostaglandin E2 promotes liver cancer cell growth by the upregulation of FUSE-binding protein 1 expression, Int J Oncol, vol.42, pp.1093-1104, 2013. ,
PI3K/AKT/mTOR-dependent stabilization of oncogenic far-upstream element binding proteins in hepatocellular carcinoma cells, Hepatology, vol.63, pp.813-826, 2016. ,
Far upstream element-binding protein 1 (FUBP1) is overexpressed in human gastric cancer tissue compared to non-cancerous tissue, Onkologie, vol.36, pp.650-655, 2013. ,
DOI : 10.1159/000355659
Far upstream element-binding protein 1(FUBP1) expression differs between human colorectal cancer and non-cancerous tissue, Neoplasma, vol.61, pp.533-540, 2014. ,
Proteome profiling of human epithelial ovarian cancer cell line TOV-112D, Mol Cell Biochem, vol.275, pp.25-55, 2005. ,
The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma. Clin Cancer Res clincanres.0352, 2016. ,
DOI : 10.1158/1078-0432.ccr-17-0352
URL : http://clincancerres.aacrjournals.org/content/24/3/659.full.pdf