) For excellent reviews on stereoselective and stereoretentive metathesis, see: a) A. H. Hoveyda, For a recent review concerning the stereoselective synthesis of Z-alkenes via traditional methods, vol.327, pp.4763-4792, 2012. ,
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, 135, 10258?10261. Sodium maleonitriledithiolate for the synthesis of Ru-1 is commercially available, vol.135, pp.181-186, 1276.
For applications in cross and self-metathesis, see: ref. 6, 7c, d), For applications in ring-opening/cross-metathesis (ROCM), see ref. 5, b), vol.55, pp.3580-3583, 1532. ,
Hoveyda reported that reactions with S2Ru-3 can be stopped by addition of technical grade ether (wet ether), see ref. 6. Our results concerning the RCM of 24 showed that the catalyst degrades in the presence of air. Reactions carried out with non-degassed THF gave in the presence of 10 mol % of catalyst conversions < 2%, Organometallics, vol.36, issue.9, pp.1880-1887, 2017. ,
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The complete deprotonation of dithiol 4 by Et2Zn was confirmed by 1 H-NMR analysis (See SI). (15) For a recent account covering the contributions of this group in the field of Ru-catalyzed metathesis reactions, Hoveyda reported poor yields of S2Ru-3 when the disodium dithiolate salt was used for its synthesis (ref. 6). (14), vol.54, pp.12729-12734, 2011. ,