[Retracted] 3'RR and 5'E immunoglobulin heavy chain enhancers are independent engines of locus remodeling

Alexis Saintamand (1, 2) , Yves Denizot (1) , Nour Ghazzaui (1) , Hussein Issaoui (1) , François Boyer (1) , Ophélie Alyssa Martin (1)

1 CRIBL - Contrôle de la Réponse Immune B et des Lymphoproliférations
2 MICMAC - Microenvironment, Cell Differentiation, Immunology and Cancer

The authors have retracted this Correspondence. After the publication of this correspondence, it came to the authors’ attention that the control RAG2−/− mouse was a RAG2−/−γc−/− mouse. This point resulted in the conclusions being considered invalid. The authors apologize to the journal and its readers for any inconvenience caused. https://doi.org/10.1038/s41423-021-00715-7

Keywords: IgH 3′ regulatory region; RAG-deficient mice; Transcriptional enhancer; Eμ; knockout mice

Domains: Life Sciences [q-bio]; Immunology

Alexis Saintamand, Yves Denizot, Nour Ghazzaui, Hussein Issaoui, François Boyer, et al.. [Retracted] 3'RR and 5'E immunoglobulin heavy chain enhancers are independent engines of locus remodeling. Cellular and molecular immunology, 2019, 16 (2), pp.198-200. ⟨10.1038/s41423-018-0171-3⟩. ⟨hal-01903466⟩