R. Applebaum and C. Austin, Long Term Care Case Management: Design and Evaluation, 1990.

C. B. Berthelsen and J. Kristensson, The content, dissemination and effects of case management interventions for informal caregivers of older adults: a systematic review, Int J Nurs Stud, vol.52, issue.5, pp.988-1002, 2015.

F. Béland, H. Bergman, and P. Lebel, A system of integrated care for older persons with disabilities in Canada: results from a randomized controlled trial, J. Gerontol. A Biol. Sci, 2006.

, Med. Sci, vol.61, pp.367-73, 2006.

I. Boutron, D. Moher, D. G. Altman, K. F. Schulz, and P. Ravaud, Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration, 2008.

, Ann Intern Med, vol.148, pp.295-309

J. Brodsky, J. Habib, and M. Hirschfeld, World Health Organization collection on long-term care, 2003.

C. M. Callahan, M. A. Boustani, F. W. Unverzagt, M. G. Austrom, T. M. Damush et al.,

, Effectiveness of collaborative care for older adults with Alzheimer disease in primary care: a randomized controlled trial, JAMA, vol.295, pp.2148-57

S. Carretero, J. Garcés, F. Ródenas, and V. Sanjosé, The informal caregiver's burden of dependent people: theory and empirical review, Arch Gerontol Geriatr, vol.49, pp.74-79, 2009.

D. Challis, R. Darton, J. Hughes, K. Stewart, and K. Weiner, Intensive care-management at home: an alternative to institutional care?, Age Ageing, vol.30, pp.409-422, 2001.

D. Challis, R. Von-abendorff, P. Brown, J. Chesterman, and J. Hughes, Care management, dementia care and specialist mental health services: an evaluation, International Journal of Geriatric Psychiatry, vol.17, pp.315-325, 2002.

W. T. Chien and Y. M. Lee, A disease management program for families of persons in Hong Kong with dementia, Psychiatr Serv, vol.59, pp.433-436, 2008.

W. T. Chien and Y. M. Lee, Randomized controlled trial of a dementia care programme for families of home-resided older people with dementia, J Adv Nurs, vol.67, pp.774-787, 2011.

P. Fox, R. Newcomer, C. Yordi, and P. Arnsberger, Lessons learned from the Medicare Alzheimer Disease Demonstration, Alzheimer Dis Assoc Disord, vol.14, issue.2, pp.87-93, 2000.

M. Godwin, L. Ruhland, I. Casson, S. Macdonald, D. Delva et al., Pragmatic controlled clinical trials in primary care: the struggle between external and internal validity, 2003.

, BMC Med Res Methodol, vol.3, p.28

P. W. Gold, Depression: A Disease of the Mind, Brain, and Body, Am J Psychiatry, vol.159, issue.11, 2002.

R. Hébert, M. Raîche, M. Dubois, N. R. Gueye, N. Dubuc et al., Impact of PRISMA, a coordination-type integrated service delivery system for frail older people in, 2010.

. Quebec, A quasi-experimental study, J Gerontol B Psychol Sci Soc Sci, vol.65, p.107

K. Hemming, T. P. Haines, P. J. Chilton, A. J. Girling, and R. J. Lilford, The stepped wedge cluster randomised trial: rationale, design, analysis, and reporting, BMJ, vol.350, p.391, 2015.

J. Higgins, D. G. Altman, P. C. Gotzsche, P. Juni, D. Moher et al., , 2011.

, Cochrane Collaboration's tool for assessing risk of bias in randomised trials, BMJ, vol.343, p.5928, 2011.

B. Janse, R. Huijsman, R. D. De-kuyper, and I. N. Fabbricotti, The effects of an integrated care intervention for the frail elderly on informal caregivers: a quasi-experimental study, BMC Geriatr, vol.14, p.58, 2014.

A. Jansen, H. Van-hout, G. Nijpels, F. Rijmen, R. Dröes et al., Effectiveness of case management among older adults with early symptoms of dementia and their primary informal caregivers: a randomized clinical trial, Int J Nurs Stud, vol.48, pp.933-976, 2011.

D. L. Kodner, The quest for integrated systems of care for frail older persons, Aging Clin Exp Res, vol.14, pp.307-313, 2002.

J. Kanter, Clinical case management: definition, principles, components, Hosp Community Psychiatry, vol.40, pp.361-68, 1989.

T. Koch, S. Iliffe, J. Manthorpe, B. Stephens, C. Fox et al., The potential of case management for people with dementia: a commentary, Int J Geriatr Psychiatry, vol.27, issue.12, pp.1305-1314, 2012.

L. Lam, J. Lee, and J. Chung, A randomized controlled trial to examine the effectiveness of case management model for community dwelling older persons with mild dementia in Hong Kong, Int J Geriatr Psychiatry, vol.25, pp.395-402, 2010.

A. C. Leung, C. Liu, N. W. Chow, . Cos, A. Lau et al., Cost-Benefit Analysis of a Case Management Project for the Community-Dwelling Frail Elderly in Hong Kong, j appl gerontol, vol.23, pp.70-85, 2004.

R. Maccarney, J. Warner, S. Iliffe, R. Van-haselen, G. M. Fisher et al., The Hawthorne Effect: a randomised, controlled trial, BMC Med Res Methodol, vol.7, p.30, 2007.

K. J. Mackee, I. Philp, G. Lamura, C. Prouskas, B. Oberg et al., The COPE index-a first stage assessment of negative impact, positive value and quality of support of caregiving in informal carers of older people, Aging Ment Health, vol.7, pp.39-52, 2003.

J. Macneil-vroomen, J. E. Bosmans, P. M. Van-de-ven, K. J. Joling, L. D. Van-mierlo et al., Community-dwelling patients with dementia and their informal caregivers with and without case management: 2-year outcomes of a pragmatic trial, J Am Med Dir Assoc, vol.16, issue.9, 2015.

S. Matsuda and M. Yamamoto, Long-term care insurance and integrated care for the aged in Japan, Int J Integr Care, vol.1, issue.3, 2001.

D. Moher, A. Liberati, J. Tetzlaff, and D. G. Altman, Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement, BMJ, vol.339, p.2535, 2009.

R. Newcomer, C. Yordi, R. Dunah, P. Fox, and A. Wilkinson, Effects of the Medicare Alzheimer's Disease Demonstration on caregiver burden and depression, Health Serv Res, vol.34, pp.669-689, 1999.

J. M. Morales-asencio, G. , E. , M. Fj, M. et al., Effectiveness of a nurse-led case management home care model in Primary Health Care. A quasi-experimental, controlled, multi-centre study, BMC Health Serv Res, vol.8, p.193, 2008.

M. Nolan, L. Mestheneos, C. Kofahl, G. M. Melchiorre, and W. Pedich, Issues and challenges in carer support: A consideration of the literature, Services for Supporting Family Carers of Elderly People in Europe: Characteristics, Coverage and Usage. Trans-European Survey Report, EUROFAMCARE Consortium, pp.15-40, 2006.

J. T. Pacala, C. Boult, K. W. Hepburn, R. A. Kane, R. L. Kane et al., Case management of older adults in health maintenance organizations, J Am Geriatr Soc, vol.43, pp.538-542, 1995.

D. Parker, S. Mills, A. J. Senior, H. Kerse, and N. , Effectiveness of interventions that assist caregivers to support people with dementia living in the community: a systematic review, Internal Journal Parsons M, vol.60, pp.86-92, 2008.

M. W. Roman and B. L. Callen, Screening Instruments for Older Adult Depressive Disorders: Updating the Evidence-Based Toolbox, Issues Ment Health Nurs, vol.29, pp.924-941, 2008.

S. Ross, N. Curry, and N. Goodwind, Case management : What it is and how it can best be implemented, 2011.

P. Snaith, What do depression rating scales measure?, The British Journal of Psychiatry, vol.163, pp.293-298, 1993.

D. Somme, H. Trouve, M. Dramé, D. Gagnon, Y. Couturier et al., Analysis of case management programs for patients with dementia: A systematic review, vol.8, pp.426-436, 2012.

D. Somme, H. Trouvé, C. Perisset, A. Corvol, J. Ankri et al., Adapting the Quebecois method for assessing implementation to the French National, 2014.

, Alzheimer Plan 2008-2012: lessons for gerontological services integration, Int J Integr Care, vol.14, p.16

S. Sörensen, M. Pinquart, and P. Duberstein, How effective are interventions with caregivers? An updated meta-analysis, Gerontologist, vol.42, pp.356-372, 2002.

D. Strech, M. Synofzik, and G. Marckmann, Systematic reviews of empirical bioethics, J Med Ethics, vol.34, pp.472-477, 2008.

R. W. Surber, Clinical case management: A guide to comprehensive treatment of serious mental illness, Sage focus editions, vol.167, 1994.

I. Vedel, M. Monette, F. Beland, J. Monette, and H. Bergman, Ten years of integrated care: backwards and forwards. The case of the province of, Int J of Integr Care, vol.11, issue.5, 2011.

A. P. Verhagen, H. C. Vet, R. A. De-bie, M. Boers, and P. Van-a-den-brandt, The art of quality assessment of RCTs included in systematic reviews, Journal of Clinical Epidemiology, vol.54, pp.651-54, 2001.

B. G. Vickrey, B. S. Mittman, K. I. Connor, M. L. Pearson, D. Penna et al., The effect of a disease management intervention on quality and outcomes of dementia care: a randomized, controlled trial, Ann. Intern. Med, vol.145, pp.713-726, 2006.

J. L. Wolff and J. D. Kasper, Caregivers of frail elders: updating a national profile, Gerontologist, vol.46, pp.344-356, 2006.

J. L. Wolff, E. Rand-giovannetti, S. Palmer, S. Wegener, L. Reider et al., , 2009.

, Caregiving and chronic care: the guided care program for families and friends, J. Gerontol. A Biol. Sci. Med. Sci, vol.64, pp.785-791

N. Wolff, Using randomized controlled trials to evaluate socially complex services: problems, challenges and recommendations, J Ment Health Policy Econ, vol.3, pp.97-109, 2000.