Targeting PUMA/Bcl-xL interaction by new specific compounds to unleash apoptotic process in cancer cells

Appala Venkata Ramana Murthy 1 Vennu Narendar Nangunoori Sampath Kumar Pasula Aparna 1 Anagani Kanaka Durga Bhavani Fabien Gautier 2 Sophie Barillé-Nion 2 Philippe Juin 2 Paul Mosset 3 René Grée 3 Nicolas Levoin 4
1 JNU - Jawaharlal Nehru University
2 CRCINA - Département ONCO - Equipe 8 - Stress Adaptation and Tumor Escape in breast cancer - SATE
CRCINA - Centre de recherche de Cancérologie et d'Immunologie / Nantes - Angers
3 ISCR - Institut des Sciences Chimiques de Rennes
4 Bioprojet-Biotech
Keywords : Molecular modelling Cancer Protein-protein interactions PUMA BRET Bcl-xL
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Submitted on : Monday, December 3, 2018 - 1:36:38 PM
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Appala Venkata Ramana Murthy, Vennu Narendar, Nangunoori Sampath Kumar, Pasula Aparna, Anagani Kanaka Durga Bhavani, et al.. Targeting PUMA/Bcl-xL interaction by new specific compounds to unleash apoptotic process in cancer cells. European Journal of Medicinal Chemistry, Elsevier, 2019, 162, pp.334-347. ⟨10.1016/j.ejmech.2018.10.069⟩. ⟨hal-01937242⟩

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