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Enhancers 134 located in heavy chain regulatory region (hs3a, hs1,2, hs3b and hs4) are dispensable for 135 diversity of VDJ recombination, J. Biol. Chem, vol.287, pp.8356-8360, 2012. ,
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Flexible long-range loops in the VH gene region of the IgH locus 139 facilitate the generation of a diverse antibody repertoire, Immunity, vol.39, pp.229-244, 2013. ,