Association of a Schizophrenia-Risk Nonsynonymous Variant With Putamen Volume in Adolescents A Voxelwise and Genome-Wide Association Study

Qiang Luo 1, 2 Qiang Chen 3 Wenjia Wang 4, 5 Sylvane Desrivières 2 Erin Burke Quinlan 2 Tianye Jia 1, 2 Christine Macare 2 Gabriel H Robert 6 Jing Cui 7 Mickael Guedj 4 Lena Palaniyappan 8 Ferath Kherif 7 Tobias Banaschewski 9 Arun L W Bokde 10 Christian Büchel Herta Flor 11, 9 Vincent Frouin 12 Hugh Garavan 13 Penny Gowland 14 Andreas Heinz Bernd Ittermann Jean-Luc Martinot 15, 16, 17 Eric Artiges 15, 18, 17 Marie-Laure Paillère-Martinot 19, 17 Frauke Nees 9 Dimitri Papadopoulos Orfanos 12 Luise Poustka 20, 21 Juliane H Fröhner 22 Michael N Smolka 22 Henrik Walter Robert Whelan Joseph H Callicott Venkata S Mattay 3, 23 Zdenka Pausova 24 Jean-François Dartigues 25 Christophe Tzourio 25 Fabrice Crivello 26 Karen F Berman Fei Li Tomáš Paus 27, 24 Daniel R Weinberger 3, 23, 28 Robin M Murray Gunter Schumann Jianfeng Feng 1, 29
Abstract : Deviation from normal adolescent brain development precedes manifestations of many major psychiatric symptoms. Such altered developmental trajectories in adolescents may be linked to genetic risk for psychopathology.
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-02020866
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Submitted on : Friday, February 15, 2019 - 2:49:08 PM
Last modification on : Thursday, April 11, 2019 - 4:02:19 PM

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Qiang Luo, Qiang Chen, Wenjia Wang, Sylvane Desrivières, Erin Burke Quinlan, et al.. Association of a Schizophrenia-Risk Nonsynonymous Variant With Putamen Volume in Adolescents A Voxelwise and Genome-Wide Association Study. JAMA Psychiatry, 2019, ⟨10.1001/jamapsychiatry.2018.4126⟩. ⟨hal-02020866⟩

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