Low interleukin-10 release after ex vivo stimulation of whole blood is associated with persistent organ dysfunction in sepsis a prospective observational study

Nicolas Nesseler 1 Corinne Martin-Chouly 2 Harmonie Perrichet 3 James T Ross 4 Chloé Rousseau 5 Pratik Sinha 4 Sonia Isslame 3 Elodie Masseret 3 Yannick Mallédant 1 Yoann Launey 1 Philippe Seguin 1
1 NuMeCan - Nutrition, Métabolismes et Cancer
2 Irset - Institut de recherche, santé, environnement et travail
3 CHU Pontchaillou [Rennes]
4 UCSF - University of California [San Francisco]
5 CIC - Centre d'Investigation Clinique [Rennes]
Keywords : lipopolysaccharide SOFA score cytokines immunosuppression endotoxin prognosis
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Nicolas Nesseler, Corinne Martin-Chouly, Harmonie Perrichet, James T Ross, Chloé Rousseau, et al.. Low interleukin-10 release after ex vivo stimulation of whole blood is associated with persistent organ dysfunction in sepsis a prospective observational study. Anaesthesia Critical Care & Pain Medicine, Elsevier Masson, In press, 38 (5), pp.485-491. ⟨10.1016/j.accpm.2019.01.009⟩. ⟨hal-02049818⟩

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