Détection précoce de la BPCO en soins primaires : un essai contrôlé randomisé

Abstract : Introduction - Chronic obstructive pulmonary disease (COPD) is a common but under-diagnosed pathology in primary care. The objective was to study the feasibility of a randomized controlled trial in general practice to detect new cases of COPD at an earlier stage. Methods - A cluster randomized, controlled, multicenter intervention study comparing, according to a 2×2 factorial plan, two case finding strategies: a systematic GOLD-HAS hetero-questionnaire and coordination of the patient's path to facilitate access to spirometry. The PIL-DISCO pilot study took place in 2017. Patients between 40 and 80 years old, with no previous history of COPD, consulting their GP on a given day regardless of the reason, were included. Results - 176 patients were included in 1.5 days. Spirometry was performed in none of the control arm, in 13 (29.5%) of the questionnaire arm, in 22 (50%) in the coordination arm and in 32 (72.7%) with the combination of the two strategies. Two cases of stage 2 COPD and thirteen other respiratory diseases were diagnosed. Conclusions - This study confirms the feasibility of the protocol in primary care in terms of speed of inclusion and acceptability. An extension phase aiming to include 3200 patients will assess the diagnostic value of the two strategies tested in general practice.
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Submitted on : Tuesday, February 26, 2019 - 4:28:45 PM
Last modification on : Thursday, July 11, 2019 - 1:35:48 PM

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A Chapron, F Pelé, É Andres, L Fiquet, C Laforest, et al.. Détection précoce de la BPCO en soins primaires : un essai contrôlé randomisé. Revue des Maladies Respiratoires, Elsevier Masson, 2019, 36 (2), pp.162-170. ⟨10.1016/j.rmr.2018.08.023⟩. ⟨hal-02049820⟩

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