Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment a prospective cohort study

Fabrice Carrat 1 Hélène Fontaine 2, 3 Céline Dorival 1 Mélanie Simony 4 Alpha Diallo Christophe Hezode 5 Victor de Ledinghen 6 Dominique Larrey 7 Georges Haour 1 Jean-Pierre Bronowicki Fabien Zoulim 8 Tarik Asselah 9 Patrick Marcellin 9 Dominique Thabut 10 Vincent Leroy 11 Albert Tran 12 François Habersetzer 13 Didier Samuel 14 Dominique Guyader 15 Olivier Chazouilleres 16 Philippe Mathurin 17 Sophie Metivier 18 Laurent Alric 18 Ghassan Riachi 19 Jérôme Gournay Armand Abergel 20, 21 Paul Calès 22, 23 Nathalie Ganne 24 Véronique Loustaud-Ratti 25 Louis d'Alteroche 26 Xavier Causse 27 Claire Geist 28 Anne Minello 29 Isabelle Rosa Moana Gelu-Simeon 30 Isabelle Portal 31 François Raffi 32 Marc Bourlière 33 Stanislas Pol 34, 2, 3, 35
29 Equipe EPICAD (LNC - U1231)
LNC - Lipides - Nutrition - Cancer [Dijon - U1231]
Abstract : Although direct-acting antivirals have been used extensively to treat patients with chronic hepatitis C virus (HCV) infection, their clinical effectiveness has not been well reported. We compared the incidence of death, hepatocellular carcinoma, and decompensated cirrhosis between patients treated with direct-acting antivirals and those untreated, in the French ANRS CO22 Hepather cohort.
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Journal articles
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-02050395
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Submitted on : Wednesday, February 27, 2019 - 10:29:14 AM
Last modification on : Friday, November 29, 2019 - 1:48:07 AM

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Fabrice Carrat, Hélène Fontaine, Céline Dorival, Mélanie Simony, Alpha Diallo, et al.. Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment a prospective cohort study. Lancet, Elsevier, 2019, 393 (10179), pp.1453-1464. ⟨10.1016/S0140-6736(18)32111-1⟩. ⟨hal-02050395⟩

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