Harvesting New Chiral Phosphotriesters by Phosphorylation of BINOL and Parent Bis-phenols - Université de Rennes Accéder directement au contenu
Article Dans Une Revue Synthesis: Journal of Synthetic Organic Chemistry Année : 2019

Harvesting New Chiral Phosphotriesters by Phosphorylation of BINOL and Parent Bis-phenols

Résumé

The systematic study on the phosphorylation of BINOL and other bisphenols operated by chlorophosphates is described. An intriguing reactivity has been observed, which is attributable to the hydroxyl group acidity and the leaving group nucleofuge character within the phosphorylating agent used. By playing on these two parameters new chiral monophosphotriesters, symmetrical homo-BINOL bisphosphates and unsymmetrical non-homo-BINOL ones, incorporating a non-chiral side unit, were synthesized selectively and in good yields.

Domaines

Chimie organique
Fichier principal
Vignette du fichier
SYNTHESIS.pdf (756.2 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-02051163 , version 1 (25-11-2020)

Identifiants

Citer

A.N. Ndimba, T. Roisnel, G. Argouarch, C. Lalli. Harvesting New Chiral Phosphotriesters by Phosphorylation of BINOL and Parent Bis-phenols. Synthesis: Journal of Synthetic Organic Chemistry, 2019, 51 (4), pp.865-873. ⟨10.1055/s-0037-1611295⟩. ⟨hal-02051163⟩
65 Consultations
160 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More