Skip to Main content Skip to Navigation
Journal articles

Harvesting New Chiral Phosphotriesters by Phosphorylation of BINOL and Parent Bis-phenols

Abstract : The systematic study on the phosphorylation of BINOL and other bisphenols operated by chlorophosphates is described. An intriguing reactivity has been observed, which is attributable to the hydroxyl group acidity and the leaving group nucleofuge character within the phosphorylating agent used. By playing on these two parameters new chiral monophosphotriesters, symmetrical homo-BINOL bisphosphates and unsymmetrical non-homo-BINOL ones, incorporating a non-chiral side unit, were synthesized selectively and in good yields.
Document type :
Journal articles
Complete list of metadatas

https://hal-univ-rennes1.archives-ouvertes.fr/hal-02051163
Contributor : Laurent Jonchère <>
Submitted on : Wednesday, November 25, 2020 - 5:08:54 PM
Last modification on : Wednesday, January 13, 2021 - 9:41:08 AM

File

SYNTHESIS.pdf
Files produced by the author(s)

Identifiers

Citation

A.N. Ndimba, T. Roisnel, G. Argouarch, C. Lalli. Harvesting New Chiral Phosphotriesters by Phosphorylation of BINOL and Parent Bis-phenols. SYNTHESIS, Georg Thieme Verlag, 2019, 51 (4), pp.865-873. ⟨10.1055/s-0037-1611295⟩. ⟨hal-02051163⟩

Share

Metrics

Record views

69

Files downloads

10