S. Ban, F. Sata, N. Kurahashi, S. Kasai, K. Moriya et al., Genetic polymorphisms of ESR1 and ESR2 that may influence estrogen activity and the risk of hypospadias, Hum Reprod, vol.23, pp.1466-1471, 2008.

T. Barrett, S. E. Wilhite, P. Ledoux, C. Evangelista, I. F. Kim et al., NCBI GEO: archive for functional genomics data sets--update, Nucleic acids research, vol.41, pp.991-995, 2013.

J. Boberg, M. Axelstad, T. Svingen, K. Mandrup, S. Christiansen et al., , 2016.

, Multiple Endocrine Disrupting Effects in Rats Perinatally Exposed to Butylparaben, Toxicological sciences : an official journal of the Society of Toxicology, vol.152, pp.244-256

J. Boberg, S. Metzdorff, R. Wortziger, M. Axelstad, L. Brokken et al., Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats, Toxicology, vol.250, pp.75-81, 2008.

C. J. Bowman, N. J. Barlow, K. J. Turner, D. G. Wallace, and P. M. Foster, Effects of in utero exposure to finasteride on androgen-dependent reproductive development in the male rat, Toxicological sciences : an official journal of the Society of Toxicology, vol.74, pp.393-406, 2003.

J. R. Byford, L. E. Shaw, M. G. Drew, G. S. Pope, M. J. Sauer et al., Oestrogenic activity of parabens in MCF7 human breast cancer cells, The Journal of steroid biochemistry and molecular biology, vol.80, pp.49-60, 2002.

F. Chalmel and M. Primig, The Annotation, Mapping, Expression and Network (AMEN) suite of tools for molecular systems biology, BMC bioinformatics, vol.9, p.86, 2008.
URL : https://hal.archives-ouvertes.fr/inserm-00521445

J. Imperato-mcginley, T. Gautier, K. Zirinsky, T. Hom, O. Palomo et al., Prostate visualization studies in males homozygous and heterozygous for 5 alpha-reductase deficiency, The Journal of clinical endocrinology and metabolism, vol.75, pp.1022-1026, 1992.

L. A. Ipulan, K. Suzuki, Y. Sakamoto, A. Murashima, Y. Imai et al., Nonmyocytic androgen receptor regulates the sexually dimorphic development of the embryonic bulbocavernosus muscle, Endocrinology, vol.155, pp.2467-2479, 2014.

R. A. Irizarry, B. M. Bolstad, C. F. Cope, L. M. Hobbs, B. Speed et al., Summaries of Affymetrix GeneChip probe level data, Nucleic acids research, vol.31, p.15, 2003.

A. Jost, Hormonal factors in the development of the fetus, Cold Spring Harbor symposia on quantitative biology, vol.19, pp.167-181, 1954.

H. S. Kim, S. Y. Han, S. D. Yoo, B. M. Lee, and K. L. Park, Potential estrogenic effects of bisphenol-A estimated by in vitro and in vivo combination assays, The Journal of toxicological sciences, vol.26, pp.111-118, 2001.

H. E. Maclean, W. S. Chiu, A. J. Notini, A. M. Axell, R. A. Davey et al., Impaired skeletal muscle development and function in male, but not female, genomic androgen receptor knockout mice, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol.22, pp.2676-2689, 2008.

J. B. Matthews, K. Twomey, and T. R. Zacharewski, In vitro and in vivo interactions of bisphenol A and its metabolite, bisphenol A glucuronide, with estrogen receptors alpha and beta, Chemical research in toxicology, vol.14, pp.149-157, 2001.

. Oecd, Extended One-Generation Reproductive Toxicity Study, OECD Guidelines for the Testing of Chemicals, 2012.

. Oecd, Test No. 421: Reproduction/Developmental Toxicity Screening Test, OECD Guidelines for the Testing of Chemicals, 2016.

. Oecd, Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test, OECD Guidelines for the Testing of Chemicals, 2016.

. Oecd, Prenatal Development Toxicity Study, OECD Guidelines for the Testing of Chemicals, vol.4, 2018.

A. K. Rosenmai, M. Dybdahl, M. Pedersen, A. Van-vugt-lussenburg, B. M. Wedebye et al., Are structural analogues to bisphenol a safe alternatives? Toxicological sciences : an official journal of the, Society of Toxicology, vol.139, pp.35-47, 2014.

E. J. Routledge, J. Parker, J. Odum, J. Ashby, and J. P. Sumpter, Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic, Toxicology and applied pharmacology, vol.153, pp.12-19, 1998.

M. R. Safarinejad, N. Shafiei, and S. Safarinejad, Association of polymorphisms in the estrogen receptors alpha, and beta (ESR1, ESR2) with the occurrence of male infertility and semen parameters, The Journal of steroid biochemistry and molecular biology, vol.122, pp.193-203, 2010.

E. Salazar-martinez, P. Romano-riquer, E. Yanez-marquez, M. P. Longnecker, and M. Hernandez-avila, Anogenital distance in human male and female newborns: a descriptive, cross-sectional study, Environ Health, vol.3, issue.8, 2004.

S. Sathyanarayana, S. H. Swan, F. M. Farin, H. W. Wilkerson, M. Bamshad et al., A pilot study of the association between genetic polymorphisms involved in estrogen signaling and infant male genital phenotypes, Asian journal of andrology, vol.14, pp.766-772, 2012.

C. L. Schwartz, S. Christiansen, A. M. Vinggaard, M. Axelstad, U. Hass et al., Anogenital distance as a toxicological or clinical marker for fetal androgen action and risk for reproductive disorders, Arch Toxicol In Press, 2018.

N. E. Skakkebaek, E. Rajpert-de-meyts, and K. M. Main, Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects, Hum Reprod, vol.16, pp.972-978, 2001.

G. K. Smyth, Linear models and empirical bayes methods for assessing differential expression in microarray experiments, Statistical applications in genetics and molecular biology, vol.3, p.3, 2004.

M. K. Stewart, D. M. Mattiske, and A. J. Pask, In utero exposure to both high-and low-dose diethylstilbestrol disrupts mouse genital tubercle development, Biology of reproduction, vol.99, pp.1184-1193, 2018.

T. Svingen and P. Koopman, Building the mammalian testis: origins, differentiation, and assembly of the component cell populations, Genes & development, vol.27, pp.2409-2426, 2013.

H. Tinwell, J. Haseman, P. A. Lefevre, N. Wallis, and J. Ashby, Normal sexual development of two strains of rat exposed in utero to low doses of bisphenol A. Toxicological sciences : an official journal of the, Society of Toxicology, vol.68, pp.339-348, 2002.

S. Van-den-driesche, K. R. Kilcoyne, I. Wagner, D. Rebourcet, A. Boyle et al., , 2017.

M. Watanabe, R. Yoshida, K. Ueoka, K. Aoki, I. Sasagawa et al., Haplotype analysis of the estrogen receptor 1 gene in male genital and reproductive abnormalities, Hum Reprod, vol.22, pp.1279-1284, 2007.

M. Welsh, P. T. Saunders, M. Fisken, H. M. Scott, G. R. Hutchison et al., Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism, J Clin Invest, vol.118, pp.1479-1490, 2008.

L. Zhang, L. Dong, S. Ding, P. Qiao, C. Wang et al., Effects of n-butylparaben on steroidogenesis and spermatogenesis through changed E(2) levels in male rat offspring, Environmental toxicology and pharmacology, vol.37, pp.705-717, 2014.

X. Zhang, M. Bolt, M. J. Guertin, W. Chen, S. Zhang et al., , 2012.

, Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor alpha target gene activation, Proceedings of the National Academy of Sciences of the United States of America, vol.109, pp.13331-13336