Power behind the throne: A clinical trial simulation study evaluating the impact of controllable design factors on the power of antidepressant trials

Astrid Chevance 1 Florian Naudet 2, 3 Raphaël Gaillard 4 Philippe Ravaud 5, 1 Raphaël Porcher 1
1 CRESS (U1153 / UMR_A_1125 / UMR_S_1153) - Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité
2 Stanford University [Stanford]
3 CIC - Centre d'Investigation Clinique [Rennes]
4 U894 / UMS 1266 - Institut de psychiatrie et neurosciences
5 Columbia University [New York]
Keywords : clinical trials antidepressants methodology depression modeling
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Submitted on : Tuesday, July 16, 2019 - 3:46:23 PM
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Astrid Chevance, Florian Naudet, Raphaël Gaillard, Philippe Ravaud, Raphaël Porcher. Power behind the throne: A clinical trial simulation study evaluating the impact of controllable design factors on the power of antidepressant trials. International Journal of Methods in Psychiatric Research, Wiley, 2019, 28 (3), pp.e1779. ⟨10.1002/mpr.1779⟩. ⟨hal-02120673⟩

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