Management of epithelial cancer of the ovary, fallopian tube, primary peritoneum. Long text of the joint French clinical practice guidelines issued by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY, endorsed by INCa. (Part 2 systemic, intraperitoneal treatment, elderly patients, fertility preservation, follow-up)

V Lavoue; C Huchon; C Akladios; P Alfonsi; N Bakrin; M Ballester; S Bendifallah; P A Bolze; F Bonnet; C Bourgin; N Chabbert-Buffet; P Collinet; Blandine Courbiere; T de la Motte Rouge; M Devouassoux-Shisheboran; C Falandry; G Ferron; L Fournier; L Gladieff; F Golfier; S Gouy; F Guyon; E Lambaudie; A Leary; F Lecuru; M A Lefrere-Belda; E Leblanc; A Lemoine; F Narducci; L Ouldamer; P Pautier; F Planchamp; N Pouget; I Ray-Coquard; C Rousset-Jablonski; C Senechal-Davin; C Touboul; I Thomassin-Naggara; C Uzan; B You; E Daraï

doi:10.1016/j.jogoh.2019.03.018

Journal articles

Management of epithelial cancer of the ovary, fallopian tube, primary peritoneum. Long text of the joint French clinical practice guidelines issued by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY, endorsed by INCa. (Part 2 systemic, intraperitoneal treatment, elderly patients, fertility preservation, follow-up)

V Lavoue ¹ C Huchon ² C Akladios ³ P Alfonsi ⁴ N Bakrin ⁵ M Ballester ⁶ S Bendifallah ⁷ P A Bolze ⁵ F Bonnet ⁷ C Bourgin ⁵ N Chabbert-Buffet ⁷ P Collinet ⁸ Blandine Courbiere ⁹ T de la Motte Rouge ¹⁰ M Devouassoux-Shisheboran ¹¹ C Falandry ¹¹ G Ferron ¹² L Fournier ¹³ L Gladieff ¹² F Golfier ⁵ S Gouy ¹⁴ F Guyon ¹⁵ E Lambaudie ¹⁶ A Leary ^{17, 18} F Lecuru ¹³ M A Lefrere-Belda ¹³ E Leblanc ¹⁹ A Lemoine ²⁰ F Narducci ¹⁹ L Ouldamer ²¹ P Pautier ^{17, 18} F Planchamp ¹⁵ N Pouget ²² I Ray-Coquard ²³ C Rousset-Jablonski ²³ C Senechal-Davin ¹⁵ C Touboul ²⁴ I Thomassin-Naggara ⁷ C Uzan ²⁵ B You ²⁶ E Daraï ⁷

1 COSS - Chemistry, Oncogenesis, Stress and Signaling

2 Service de gynécologie et obstétrique [CHI Poissy-Saint Germain]

3 CHU Strasbourg

4 Hôpital Saint-Luc-Saint-Joseph, service anesthésie-réanimation

5 Service d’Urologie [CHU Lyon Sud]

6 Groupe Hospitalier Diaconesses Croix Saint-Simon

7 CHU Tenon [APHP]

8 Hôpital Jeanne de Flandres, CHRU de Lille,

9 IMBE - Institut méditerranéen de biodiversité et d'écologie marine et continentale

10 CRLCC - Centre Eugène Marquis

11 CHLS - Centre Hospitalier Lyon Sud [CHU - HCL]

12 CRLCC Institut Claudius Regaud

13 AP-HP - Hôpital Européen Georges Pompidou, Assistance Publique – Hôpitaux de Paris

14 Département de chirurgie gynécologique [Gustave Roussy]

15 Institut Bergonié - CRLCC Bordeaux

16 Institut Paoli-Calmettes

17 IGR - Institut Gustave Roussy

18 Oncologie gynécologique

Département de médecine oncologique [Gustave Roussy]

19 CRLCC Oscar Lambret

20 AP-HP - Hôpital Tenon, Assistance Publique - Hôpitaux de Paris

21 Département d’Hématologie Clinique [CHU Tours]

22 Institut Curie

23 Centre Léon Bérard [Lyon]

24 CHIC - Centre Hospitalier Intercommunal de Créteil

25 CR Saint-Antoine - Centre de Recherche Saint-Antoine

26 HCL - Hospices Civils de Lyon

Abstract : Adjuvant chemotherapy by carboplatin and paclitaxel is recommended for all high-grade ovarian and tubal cancers (FIGO stages I-IIA) (grade A). After primary surgery is complete, 6 cycles of intravenous chemotherapy (grade A) are recommended, or a discussion with the patient about intraperitoneal chemotherapy, according to her risk-benefit ratio. After complete interval surgery for FIGO stage III, hyperthermic intraperitoneal chemotherapy (HIPEC) can be proposed, in accordance with the modalities of the OV-HIPEC trial (grade B). In cases of postoperative tumor residue or in FIGO stage IV tumors, chemotherapy associated with bevacizumab is recommended (grade A).

Keywords : Surgery Primary peritoneal cancer Ovarian cancer Chemotherapy Guidelines Tubal cancer

Domain :

Life Sciences [q-bio] / Cancer

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V Lavoue, C Huchon, C Akladios, P Alfonsi, N Bakrin, et al.. Management of epithelial cancer of the ovary, fallopian tube, primary peritoneum. Long text of the joint French clinical practice guidelines issued by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY, endorsed by INCa. (Part 2 systemic, intraperitoneal treatment, elderly patients, fertility preservation, follow-up). Journal of Gynecology Obstetrics and Human Reproduction, Elsevier, 2019, 48 (6), pp.379-386. ⟨10.1016/j.jogoh.2019.03.018⟩. ⟨hal-02121103⟩

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