Management of epithelial cancer of the ovary, fallopian tube, primary peritoneum. Long text of the joint French clinical practice guidelines issued by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY, endorsed by INCa. (Part 2 systemic, intraperitoneal treatment, elderly patients, fertility preservation, follow-up)

V Lavoue 1 C Huchon 2 C Akladios 3 P Alfonsi 4 N Bakrin 5 M Ballester 6 S Bendifallah 7 P A Bolze 5 F Bonnet 7 C Bourgin 5 N Chabbert-Buffet 7 P Collinet 8 B Courbiere 9 T de La Motte Rouge 10 M Devouassoux-Shisheboran 11 C Falandry 11 G Ferron 12 L Fournier 13 L Gladieff 12 F Golfier 5 S Gouy 14 F Guyon 15 E Lambaudie 16 A Leary 17, 18 F Lecuru 13 M A Lefrere-Belda 13 E Leblanc 19 A Lemoine 20 F Narducci 19 L Ouldamer 21 P Pautier 17, 18 F Planchamp 15 N Pouget 22 I Ray-Coquard 23 C Rousset-Jablonski 23 C Senechal-Davin 15 C Touboul 24 I Thomassin-Naggara 7 C Uzan 25 B You 26 E Daraï 7
Abstract : Adjuvant chemotherapy by carboplatin and paclitaxel is recommended for all high-grade ovarian and tubal cancers (FIGO stages I-IIA) (grade A). After primary surgery is complete, 6 cycles of intravenous chemotherapy (grade A) are recommended, or a discussion with the patient about intraperitoneal chemotherapy, according to her risk-benefit ratio. After complete interval surgery for FIGO stage III, hyperthermic intraperitoneal chemotherapy (HIPEC) can be proposed, in accordance with the modalities of the OV-HIPEC trial (grade B). In cases of postoperative tumor residue or in FIGO stage IV tumors, chemotherapy associated with bevacizumab is recommended (grade A).
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Submitted on : Wednesday, May 29, 2019 - 4:37:08 PM
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V Lavoue, C Huchon, C Akladios, P Alfonsi, N Bakrin, et al.. Management of epithelial cancer of the ovary, fallopian tube, primary peritoneum. Long text of the joint French clinical practice guidelines issued by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY, endorsed by INCa. (Part 2 systemic, intraperitoneal treatment, elderly patients, fertility preservation, follow-up). Journal of Gynecology Obstetrics and Human Reproduction, Elsevier, 2019, 48 (6), pp.379-386. ⟨10.1016/j.jogoh.2019.03.018⟩. ⟨hal-02121103⟩

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