Metallodrugs in Medicinal Inorganic Chemistry, Chem. Rev, vol.114, pp.4540-4563, 2014. ,
Cisplatin: Its History and Possible Mechanisms of Action, vol.9, p.20, 1980. ,
Improving the safety of metal-based drugs by tuning their metabolism with chemoprotective agents, J. Inorg. Biochem, vol.179, pp.154-157, 2018. ,
Anticancer metallodrugs: where is the next cisplatin, Future Med. Chem, vol.10, pp.615-617, 2018. ,
, Damaging Agents in Cancer Chemotherapy: Serendipity and Chemical Biology. Chem. Biol, vol.20, pp.648-659, 2013.
RNA as a drug target: chemical, modelling, and evolutionary tools, Curr. Opin. Biotechnol, vol.9, pp.66-73, 1998. ,
Far-red fluorescent probes for canonical and noncanonical nucleic acid structures: current progress and future implications, Chem. Soc. Rev, vol.47, pp.1098-1131, 2018. ,
Structural Transitions in Polyriboadenylic Acid Induced by the Changes in pH and Temperature: Vibrational Circular Dichroism Study in Solution and Film States, J. Phys. Chem. B, vol.109, 2005. ,
Strategies for the design of drugs targeting RNA and RNA?protein complexes, Angew. Chem., Int. Ed, 1890. ,
RNA in unexpected places: long non? coding RNA functions in diverse cellular contexts, Nat. Rev. Mol. Cell Biol, vol.14, pp.699-712, 2013. ,
A Structural Basis for RNA?Ligand Interactions, Chem. Rev, vol.97, pp.1489-1513, 1997. ,
Principles for targeting RNA with drug-like small molecules, Nat. Rev. Drug Discovery, vol.17, pp.547-558, 2018. ,
Targeting RNA with small molecules, Chem. Rev, vol.108, pp.1171-1224, 2008. ,
Strategies for the design of RNA?binding small molecules, Future Med. Chem, vol.2, pp.93-119, 2010. ,
Recent advances in developing small molecules targeting RNA, ACS Chem. Biol, vol.7, pp.73-86, 2012. ,
Chiral Sugars Drive Enantioenrichment in Prebiotic Amino Acid Synthesis, ACS Cent. Sci, vol.3, pp.322-328, 2017. ,
Stereochemistry in Drug Action, Prim. Care Companion J. Clin. Psychiatry, vol.5, pp.70-73, 2003. ,
Racemic mixtures and single stereoisomers: Industrial concerns and issues in drug development, Chirality, vol.3, pp.94-98, 1991. ,
,
, Heterocyclic Schiff base transition metal complexes in antimicrobial and anticancer chemotherapy, MedChemComm, vol.9, pp.409-436, 2018.
Study on potential antitumor mechanism of a novel Schiff Base copper(II) complex: Synthesis, crystal structure, DNA binding, cytotoxicity and apoptosis induction activity, J. Inorg. Biochem, pp.105-728, 2011. ,
Biological Evaluation, and Quantitative Structure-Activity Relationship Analysis of New Schiff Bases of Hydroxysemicarbazide as Potential Antitumor Agents, J. Med. Chem, vol.45, pp.410-419, 2002. ,
DNA Binding Studies of Novel Copper(II) Complexes Containing L?Tryptophan as Chiral Auxiliary: In Vitro Antitumor Activity of Cu?Sn 2 Complex in Human Neuroblastoma Cells, Inorg. Chem, vol.46, pp.3072-3082, 2007. ,
Exploiting the biological efficacy of benzimidazole based Schiff base complexes with L-Histidine as a co-ligand: Combined molecular docking, DNA interaction, antimicrobial and cytotoxic studies, Bioorg. Chem, vol.77, pp.269-279, 2018. ,
Mechanistic insights into a novel chromone appended Cu(II) anticancer drug entity: in vitro binding profile with DNA/ RNA substrates and cytotoxic activity against MCF-7 and HepG2 cancer cells, Dalton Trans, vol.44, pp.10330-10342, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01168331
,
, Enantiomeric Specificity of Biologically Significant Cu(II) and Zn(II) Chromone Complexes Towards DNA, Chirality, vol.24, pp.977-986, 2012.
Interaction of Amino Acid Schiff Base Metal Complexes with DNA/BSA Protein and Antibacterial Activity: Spectral Studies, DFT Calculations and Molecular Docking Simulations, Appl. Organomet. Chem, vol.32, issue.e4259, 2018. ,
DNA binding, antioxidant and antimicrobial activities of homo-and heteronuclear copper(II) and nickel(II) complexes with new oxime-type ligands, Eur. J. Med. Chem, pp.5169-5175, 2010. ,
New Roles for Copper Metabolism in Cell Proliferation, Signaling, and Disease, J. Biol. Chem, vol.284, pp.717-721, 2009. ,
Hypotoxic copper complexes with potent anti-metastatic and anti-angiogenic activities against cancer cells, Dalton Trans, vol.47, pp.5049-5054, 2018. ,
, Copper Complexes as Anticancer Agents. Anti-Cancer Agents Med. Chem, vol.9, pp.185-211, 2009.
Targeting copper in cancer therapy: 'Copper That Cancer, vol.7, pp.1459-1476, 2015. ,
Copper Binding Agents Acting as Copper Ionophores Lead to Caspase Inhibition and Paraptotic Cell Death in Human Cancer Cells, J. Am. Chem. Soc, vol.133, pp.6235-6242, 2011. ,
Cellular and computational studies of proteasome inhibition and apoptosis induction in human cancer cells by amino acid Schiff base?copper complexes, J. Inorg. Biochem, vol.118, pp.83-93, 2013. ,
Selective anticancer copper(II)-mixed ligand complexes: targeting of ROS and proteasomes, Metallomics, vol.6, pp.892-906, 2014. ,
Crystal structures, DNA-binding and cytotoxic activities studies of Cu(II) complexes with 2-oxoquinoline-3-carbaldehyde Schiff-bases, Eur. J. Med. Chem, pp.45-5353, 2010. ,
Spectroscopic and Photophysical Studies of the Binding Interactions between Copper Phenanthroline Complexes and RNA, Inorg. Chem, vol.32, pp.2919-2923, 1993. ,
Synthesis, structure, DNA binding and cleavage properties of ternary amino acid Schiff base?phen/bipy Cu(II) complexes, J. Inorg. Biochem, pp.105-1603, 2011. ,
Mixed-Ligand Copper(II) Maltolate Complexes: Synthesis, Characterization, DNA Binding and Cleavage, and Cytotoxicity, Inorg. Chem, vol.48, pp.9120-9132, 2009. ,
Syntheses, structural properties and catecholase activity of copper(II) complexes with reduced Schiff base N? (2-hydroxybenzyl)-amino acids, Dalton Trans, pp.113-121, 2004. ,
Induction of Cell Death by Ternary Copper(II) Complexes of L-Tyrosine and Diimines: Role of Coligands on DNA Binding and Cleavage and Anticancer Activity, Inorg. Chem, vol.48, pp.1309-1322, 2009. ,
Synthesis, characterization, DNA/BSA interactions and anticancer activity of achiral and chiral copper complexes, Dalton Trans, vol.44, pp.9516-9527, 2015. ,
Synthesis, structure, and spectroscopic properties of copper(II) compounds containing nitrogen?sulphur donor ligands; the crystal and molecular structure of aqua[1,7-bis(N-methylbenzimidazol-2?-yl)-2,6-dithiaheptane]copper(II) perchlorate, J. Chem. Soc, vol.0, pp.1349-1356, 1984. ,
Copper complexes based on chiral Schiffbase ligands: DNA/BSA binding ability, DNA cleavage activity, cytotoxicity and mechanism of apoptosis, Eur. J. Med. Chem, vol.114, pp.244-256, 2016. ,
Five novel dinuclear copper(II) complexes: Crystal structures, properties, Hirshfeld surface analysis and vitro antitumor activity study, Inorg. Chim. Acta, vol.453, pp.507-515, 2016. ,
Interactions of copper complexes with nucleic acids, Coord. Chem. Rev, vol.360, pp.92-121, 2018. ,
Potentially cytotoxic new copper(II) hydrazone complexes: synthesis, crystal structure and biological properties, Dalton Trans, vol.42, pp.7210-7223, 2013. ,
In Vitro Biomolecular Interaction Studies and Cytotoxic Activities of Newly Synthesised Copper(II) Complexes Bearing 2-Hydroxynaphthaldehyde-Based Thiosemicarbazone, vol.3, pp.8118-8130, 2018. ,
DNA binding and cytotoxicity of two Cu(II) complexes containing a Schiff base ligand along with 1,10-phenanthroline or imidazole as a coligand, Inorg. Chim. Acta, vol.478, pp.211-221, 2018. ,
Study on nucleic acid (CT-DNA and yeast tRNA) binding behaviors and cytotoxic properties of a heterodinuclear Ru(II)?Co(III) polypyridyl complex, J. Inorg. Biochem, vol.104, pp.1259-1266, 2010. ,
Multiply Intercalator-Substituted Cu(II) Cyclen Complexes as DNA Condensers and DNA/RNA, Synthesis Inhibitors. Inorg. Chem, vol.57, pp.5004-5012, 2018. ,
DNA-and RNA binding and enhanced DNA-photocleavage properties of a ferrocenyl-containing ruthenium(II) complex, J. Inorg. Biochem, vol.107, pp.104-110, 2012. ,
Interaction of Cu-dipeptide complexes with Calf Thymus DNA and antiproliferative activity of [Cu(ala-phe)] in osteosarcoma-derived cells, Polyhedron, vol.28, pp.2329-2334, 2009. ,
DNA-fiber EPR spectroscopy as a tool to study DNA-metal complex interactions: DNA binding of hydrated Cu(II) ions and Cu(II) complexes of amino acids and peptides, J. Inorg. Biochem, vol.102, pp.1016-1024, 2008. ,
How amino acids control the binding of Cu(II) ions to DNA (II): Effect of basic amino acid residues and the chirality on the orientation of the complexes, J. Inorg. Biochem, vol.66, pp.131-139, 1997. ,
,
How amino acids control the binding of Cu(II) ions to DNA Part III. A novel interaction of a histidine complex with DNA, J. Inorg. Biochem, vol.78, pp.243-249, 2000. ,
Substitution-Inert Trinuclear Platinum Complexes Efficiently Condense/Aggregate Nucleic Acids and Inhibit Enzymatic Activity, Angew. Chem., Int. Ed, vol.53, pp.12812-12816, 2014. ,
A. C. C. Controlling the Morphology in DNA Condensation and Precipitation, Biomacromolecules, vol.10, pp.1319-1323, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00302581
Competition between compaction of single chains and bundling of multiple chains in giant DNA molecules, J. Chem. Phys, vol.120, pp.4004-4011, 2004. ,
Salt-Controlled Intrachain/Interchain Segregation in DNA Complexed with Polycation of Natural Origin. Macromolecules, vol.38, pp.9359-9365, 2005. ,
Characterization of polyplexes involving small RNA, J. Colloid Interface Sci, vol.387, pp.84-94, 2012. ,
Oxidative Cleavage of DNA by a New Ferromagnetic Linear Trinuclear Copper(II) Complex in the Presence of H 2 O 2 / Sodium Ascorbate, Inorg. Chem, vol.42, pp.2992-2998, 2003. ,
DNA Cleavage by Copper-ATCUN Complexes. Factors Influencing Cleavage Mechanism and Linearization of dsDNA, J. Am. Chem. Soc, vol.127, pp.8408-8415, 2005. ,
Cleavage of RNA phosphodiester bonds by small molecular entities: a mechanistic insight, Org. Biomol. Chem, vol.9, pp.1687-1703, 2011. ,
Synthesis, crystal structure and antiproliferative activity of Cu(II) nalidixic acid? DACH conjugate: Comparative in vitro DNA/RNA binding profile, cleavage activity and molecular docking studies, Eur. J. Med. Chem, vol.81, pp.76-88, 2014. ,
Copper complexes as prospective anticancer agents: in vitro and in vivo evaluation, selective targeting of cancer cells by DNA damage and S phase arrest, RSC Adv, vol.8, pp.16973-16990, 2018. ,
Pharmacomodulation on Gold?NHC complexes for anticancer applications -is lipophilicity the key point?, Eur. J. Med. Chem, vol.157, pp.320-332, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02407036
Docking Studies on DNA Intercalators, J. Chem. Inf. Model, vol.54, pp.96-107, 2014. ,
SHELXT ? Integrated space-group and crystal structure determination, Acta Cryst, vol.71, pp.3-8, 2015. ,
Crystal structure refinement with SHELXL ,
, Acta Crystallogr., Sect. C: Struct. Chem, vol.71, pp.3-8, 2015.
A Multipurpose Crystallographic Tool, Cryst. Eng. Comm, vol.11, issue.71, pp.19-32, 1998. ,
Design, synthesis and crystal structure determination of dinuclear copper-based potential chemotherapeutic drug entities: in vitro DNA binding, cleavage studies and an evaluation of genotoxicity by micronucleus test and comet assay, MedChemComm, vol.4, pp.394-405, 2013. ,
Quenching of Fluorescence by Oxygen. A Probe for Structural Fluctuations in Macromolecules, Biochemistry, vol.12, pp.4161-4170, 1973. ,
Hex Server: an FFT-based protein docking server powered by graphics processors, Nucleic Acids Res, vol.38, pp.445-449, 2010. ,
Sulforhodamine B colorimetric assay for cytotoxicity screening, Nat. Protoc, vol.1, pp.1112-1116, 2006. ,