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Clinical and dosimetric considerations for Y90 recommendations from an international multidisciplinary working group

Riad Salem Siddharth A Padia 1 Marnix Lam 2 Jon Bell Carlo Chiesa 3 Kirk Fowers Bonnie Hamilton Joseph Herman 4 S Cheenu Kappadath 4 Thomas Leung Lorraine Portelance 5 Daniel Sze 6 Etienne Garin 7
1 UCLA - University of California [Los Angeles]
2 University Medical Center [Utrecht]
3 IRCCS - Istituti di Ricovero e Cura a Carattere Scientifico
4 The University of Texas M.D. Anderson Cancer Center [Houston]
5 UMMSM - University of Miami Leonard M. Miller School of Medicine
6 Stanford University School of Medicine [CA, USA]
7 NuMeCan - Nutrition, Métabolismes et Cancer
Abstract : The TheraSphere Global Dosimetry Steering Committee was formed in 2017 by BTG International to review existing data and address gaps in knowledge related to dosimetry. This committee is comprised of health care providers with diverse areas of expertise and perspectives on radiation dosimetry. The goal of these recommendations is to optimize glass microspheres radiation therapy for hepatocellular carcinoma while accounting for variables including disease presentation, tumour vascularity, liver function, and curative/palliative intent. The recommendations aim to unify glass microsphere users behind standardized dosimetry methodology that is simple, reproducible and supported by clinical data, with the overarching goal of improving clinical outcomes and advancing the knowledge of dosimetry.
Keywords : Yttrium-90 Radioembolization Hepatocellular carcinoma Liver cancer
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Journal articles
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-02152867
Contributor : Laurent Jonchère <>
Submitted on : Tuesday, June 11, 2019 - 5:25:31 PM
Last modification on : Sunday, October 25, 2020 - 7:06:01 AM

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Riad Salem, Siddharth A Padia, Marnix Lam, Jon Bell, Carlo Chiesa, et al.. Clinical and dosimetric considerations for Y90 recommendations from an international multidisciplinary working group. European Journal of Nuclear Medicine and Molecular Imaging, Springer Verlag (Germany), 2019, 46 (8), pp.1695-1704. ⟨10.1007/s00259-019-04340-5⟩. ⟨hal-02152867⟩

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