Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas

An-An Yin , Ya-Long He , Amandine Etcheverry (1) , Yu-He Liu , Marc Aubry (2, 1) , Jill Barnholtz-Sloan (3) , Bo-Lin Liu , Jean Mosser (2, 4, 1) , Zi-Fan Lu , Xiang Zhang

1 IGDR - Institut de Génétique et Développement de Rennes
2 Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
3 Case Western Reserve University [Cleveland]
4 Plateforme Génomique Santé Biogenouest®

Mots clés: DNA methylation; Predictive biomarker; Temozolomide; Glioblastoma; Glioma-CpGs island methylator phenotype

Domaines: Sciences du Vivant [q-bio]

An-An Yin, Ya-Long He, Amandine Etcheverry, Yu-He Liu, Marc Aubry, et al.. Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas. Clinical Epigenetics, 2019, 11 (1), pp.76. ⟨10.1186/s13148-019-0670-9⟩. ⟨hal-02153239⟩