Synthesis and biological studies of new quinazolines with ether functions in position 2 - Archive ouverte HAL Access content directly
Journal Articles ARKIVOC - Online Journal of Organic Chemistry Year : 2019

Synthesis and biological studies of new quinazolines with ether functions in position 2

A.K.D. Bhavani
  • Function : Correspondent author
P. Aparna
  • Function : Author
N.S. Kumar
  • Function : Author
H. Solhi
  • Function : Author
Paul Mosset
R. Grée
  • Function : Correspondent author
Rémy Le Guével
  • Function : Author
  • PersonId : 835989

Abstract

A series of new quinazolines linked to triazoles through an ether chain in position 2 has been designed and synthetized through a flexible route. Cytotoxicity assays on selected cancer cell lines and inhibition studies toward a panel of representative mammalian kinases have been performed on these molecules.
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Dates and versions

hal-02161844 , version 1 (09-07-2020)

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D. Brahmaiah, A.K.D. Bhavani, P. Aparna, N.S. Kumar, H. Solhi, et al.. Synthesis and biological studies of new quinazolines with ether functions in position 2. ARKIVOC - Online Journal of Organic Chemistry, 2019, 2019 (5), pp.96-107. ⟨10.24820/ark.5550190.p010.859⟩. ⟨hal-02161844⟩
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