F. G. Fowkes, D. Rudan, I. Rudan, V. Aboyans, J. O. Denenberg et al., Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis, Lancet. Lond. Engl, vol.382, pp.1329-1340, 2013.
URL : https://hal.archives-ouvertes.fr/hal-00925590

M. H. Criqui and V. Aboyans, Epidemiology of peripheral artery disease, Circ. Res, vol.116, pp.1509-1526, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01233163

N. Wolosker, L. Nakano, R. A. Rosoky, and P. Puech-leao, Evaluation of walking capacity over time in 500 patients with intermittent claudication who underwent clinical treatment, Arch. Intern. Med, vol.163, pp.2296-2300, 2003.

L. Norgren, W. R. Hiatt, J. A. Dormandy, M. R. Nehler, K. A. Harris et al., Inter-society consensus for the management of peripheral arterial disease (TASC II), Eur. J. Vasc. Endovasc. Surg. Off. J. Eur. Soc. Vasc. Surg, vol.33, pp.1-75, 2007.

A. T. Hirsch, M. H. Criqui, D. Treat-jacobson, J. G. Regensteiner, M. A. Creager et al., Peripheral arterial disease detection, awareness, and treatment in primary care, JAMA, vol.286, pp.1317-1324, 2001.

F. G. Fowkes, E. Housley, E. H. Cawood, C. C. Macintyre, C. V. Ruckley et al., Edinburgh artery study: prevalence of asymptomatic and symptomatic peripheral arterial disease in the general population, Int. J. Epidemiol, vol.20, pp.384-392, 1991.

M. M. Mcdermott, S. Mehta, and P. Greenland, Exertional leg symptoms other than intermittent claudication are common in peripheral arterial disease, Arch. Intern. Med, vol.159, pp.387-392, 1999.

M. M. Mcdermott, L. Fried, E. Simonsick, S. Ling, and J. M. Guralnik, Asymptomatic peripheral arterial disease is independently associated with impaired lower extremity functioning: the women's health and aging study, Circulation, vol.101, pp.1007-1012, 2000.

M. M. Mcdermott, P. Greenland, K. Liu, J. M. Guralnik, M. H. Criqui et al., Leg symptoms in peripheral arterial disease: associated clinical characteristics and functional impairment, JAMA, vol.286, pp.1599-1606, 2001.

M. M. Mcdermott, L. Tian, K. Liu, J. M. Guralnik, L. Ferrucci et al., Prognostic value of functional performance for mortality in patients with peripheral artery disease, J. Am. Coll. Cardiol, vol.51, pp.1482-1489, 2008.

A. Aber, E. Lumley, P. Phillips, H. B. Woods, G. Jones et al., Themes that determine quality of life in patients with peripheral arterial disease: a systematic review, The Patient, vol.11, issue.5, pp.489-502, 2018.

M. M. Mcdermott, Functional impairment in peripheral artery disease and how to improve it in 2013, Curr. Cardiol. Rep, vol.15, p.347, 2013.

M. Tendera, V. Aboyans, M. Bartelink, I. Baumgartner, and D. Clément, ESC guidelines on the diagnosis and treatment of peripheral artery diseases: document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries: the task force on the diagnosis and treatment of peripheral artery diseases of the European Society of Cardiology (ESC), Eur. Heart J, vol.32, pp.2851-2906, 2011.

R. Bedenis, M. Stewart, M. Cleanthis, P. Robless, D. P. Mikhailidis et al., Cilostazol for intermittent claudication, Cochrane Database Syst. Rev, issue.10, p.3748, 2014.

C. T. Supuran, A. Mastrolorenzo, G. Barbaro, and A. Scozzafava, Phosphodiesterase 5 inhibitors-drug design and differentiation based on selectivity, pharmacokinetic and efficacy profiles, Curr. Pharm. Des, vol.12, pp.3459-3465, 2006.

M. Guazzi, Sildenafil and phosphodiesterase-5 inhibitors for heart failure, Curr. Heart Fail. Rep, vol.5, pp.110-114, 2008.

T. Reffelmann and R. A. Kloner, Therapeutic potential of phosphodiesterase 5 inhibition for cardiovascular disease, Circulation, vol.108, pp.239-244, 2003.

B. T. Roseguini, D. M. Hirai, M. C. Alencar, R. P. Ramos, B. M. Silva et al., Sildenafil improves skeletal muscle oxygenation during exercise in men with intermittent claudication, Am. J. Phys. Regul. Integr. Comp. Phys, vol.307, pp.396-404, 2014.

L. Omarjee, A. Camarzana, S. Henni, P. Abraham, N. et al., Vascular Pharmacology, p.106563, 2019.

, claudication improved with sildenafil: a case report, p.6186, 2017.

E. J. Turtle, I. D. Drummond, and D. J. Webb, Improvement in symptoms of peripheral arterial disease with sildenafil therapy, Scott. Med. J, vol.58, pp.7-9, 2013.

D. P. Alves, P. G. Da-motta, T. R. Romero, A. Klein, and I. D. Duarte, NO/cGMP production is important for the endogenous peripheral control of hyperalgesia during inflammation, Nitric Oxide Biol. Chem, vol.28, pp.8-13, 2013.

P. A. Sperandio, M. F. Oliveira, M. K. Rodrigues, D. C. Berton, E. Treptow et al., Sildenafil improves microvascular O2 delivery-to-utilization matching and accelerates exercise O2 uptake kinetics in chronic heart failure, Am. J. Physiol. Heart Circ. Physiol, vol.303, pp.1474-1480, 2012.

V. Aboyans, M. H. Criqui, P. Abraham, M. A. Allison, M. A. Creager et al., Measurement and interpretation of the ankle-brachial index: a scientific statement from the American Heart Association, Circulation, vol.126, pp.2890-2909, 2012.
URL : https://hal.archives-ouvertes.fr/hal-00921590

P. Abraham, J. Picquet, B. Vielle, D. Sigaudo-roussel, F. Paisant-thouveny et al., Transcutaneous oxygen pressure measurements on the buttocks during exercise to detect proximal arterial ischemia: comparison with arteriography, Circulation, vol.107, pp.1896-1900, 2003.

G. Mahé, A. Kaladji, A. L. Faucheur, and V. Jaquinandi, Internal iliac artery stenosis: diagnosis and how to manage it in 2015, Front Cardiovasc, p.33, 2015.

G. Mahe, M. Kalra, P. Abraham, D. A. Liedl, and P. W. Wennberg, Application of exercise transcutaneous oxygen pressure measurements for detection of proximal lower extremity arterial disease: a case report, Vasc. Med. Lond. Engl, vol.20, pp.251-255, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01134269

C. Koch, E. Chauve, S. Chaudru, A. L. Faucheur, V. Jaquinandi et al., Exercise transcutaneous oxygen pressure measurement has good sensitivity and specificity to detect lower extremity arterial stenosis assessed by computed tomography angiography, Medicine (Baltimore), vol.95, p.4522, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01397595

G. Mahé, N. Ouedraogo, G. Leftheriotis, B. Vielle, J. Picquet et al., Exercise treadmill testing in patients with claudication, with and without diabetes, Diabet. Med. J. Br. Diabet Assoc, vol.28, pp.356-362, 2011.

M. Radicioni, C. Castiglioni, A. Giori, I. Cupone, V. Frangione et al., Bioequivalence study of a new sildenafil 100 mg orodispersible film compared to the conventional film-coated 100 mg tablet administered to healthy male volunteers, Drug. Des. Devel. Ther, vol.11, pp.1183-1192, 2017.

K. Andersson, PDE5 inhibitors -pharmacology and clinical applications 20 years after sildenafil discovery, Br. J. Pharmacol, vol.175, pp.2554-2565, 2018.

R. A. Kloner, I. Goldstein, M. G. Kirby, J. D. Parker, and R. Sadovsky, Cardiovascular safety of phosphodiesterase type 5 inhibitors after nearly 2 decades on the market, Sex Med. Rev, vol.6, issue.4, pp.583-594, 2018.

S. P. Nicolaï, W. Viechtbauer, L. M. Kruidenier, M. J. Candel, M. H. Prins et al., Reliability of treadmill testing in peripheral arterial disease: a metaregression analysis, J. Vasc. Surg, vol.50, pp.322-329, 2009.

H. G. Lee, W. M. Kim, J. I. Choi, and M. H. Yoon, Roles of adenosine receptor subtypes on the antinociceptive effect of sildenafil in rat spinal cord, Neurosci. Lett, vol.480, pp.182-185, 2010.

F. A. Rocha, F. S. Silva, A. Leite, A. Leite, V. Girão et al., Tadalafil analgesia in experimental arthritis involves suppression of intra-articular TNF release, Br. J. Pharmacol, vol.164, pp.828-835, 2011.

H. Chen, F. Wang, W. Chen, X. Ye, . Ting et al., efficacy of daily lowdose sildenafil for treating interstitial cystitis: results of a randomized, double-blind, placebo-controlled trial-treatment of interstitial cystitis/painful bladder syndrome with low-dose sildenafil, Urology, vol.84, pp.51-56, 2014.

M. T. Gonçalves-de-medeiros, R. B. De-oliveira, A. A. Santos, D. M. De-leopoldino, M. C. Lima et al., The effects of sildenafil on rectal sensitivity and tone in patients with the irritable bowel syndrome, Aliment. Pharmacol. Ther, vol.35, pp.577-586, 2012.

T. Komiyama, H. Shigematsu, H. Yasuhara, and T. Muto, Near-infrared spectroscopy grades the severity of intermittent claudication in diabetics more accurately than ankle pressure measurement, Br. J. Surg, vol.87, pp.459-466, 2000.

T. Komiyama, H. Shigematsu, H. Yasuhara, and T. Muto, An objective assessment of intermittent claudication by near-infrared spectroscopy, Eur. J. Vasc. Surg, vol.8, pp.294-296, 1994.

M. Ferrari and V. Quaresima, Near infrared brain and muscle oximetry: from the discovery to current applications, J. Infrared. Spectrosc. [Internet], vol.20, pp.1-14, 2012.

Q. Zhang, W. Yuan, G. Wang, J. Wu, M. Wang et al., The protective effects of a phosphodiesterase 5 inhibitor, sildenafil, on postresuscitation cardiac dysfunction of cardiac arrest: metabolic evidence from microdialysis, Crit. Care Lond. Engl, vol.18, p.641, 2014.

M. D. Cheitlin, A. M. Hutter, R. G. Brindis, P. Ganz, S. Kaul et al., ACC/ AHA expert consensus document. Use of sildenafil (Viagra) in patients with cardiovascular disease, American College of Cardiology/American Heart Association, vol.33, pp.273-282, 1999.

G. V. Guimaraes, V. M. Avila, P. Pires, F. Bacal, N. Stolf et al., Acute effects of a single dose of phosphodiesterase type 5 inhibitor (sildenafil) on systemic arterial blood pressure during exercise and 24-hour ambulatory blood pressure monitoring in heart transplant recipients, Transplant. Proc, vol.39, pp.3142-3149, 2007.

Y. Vardi, M. Bulus, S. Reisner, S. Nassar, L. Aboud et al., Effects of sildenafil citrate (Viagra) on hemodynamic parameters during exercise testing and occurrence of ventricular arrhythmias in patients with erectile dysfunction and cardiovascular disease, Eur. Urol, vol.43, pp.544-551, 2003.

E. F. Bakke, J. Hisdal, J. J. Jørgensen, A. Kroese, and E. Stranden, Blood pressure in patients with intermittent claudication increases continuously during walking, Eur. J. Vasc. Endovasc. Surg. Off. J. Eur. Soc. Vasc. Surg, vol.33, pp.20-25, 2007.

I. I. De-liefde, S. E. Hoeks, Y. R. Van-gestel, J. J. Bax, J. Klein et al., Usefulness of hypertensive blood pressure response during a single-stage exercise test to predict long-term outcome in patients with peripheral arterial disease, Am. J. Cardiol, vol.102, pp.921-926, 2008.

R. A. Kloner, Pharmacology and drug interaction effects of the phosphodiesterase 5 inhibitors: focus on alpha-blocker interactions, Am. J. Cardiol, vol.96, pp.42-46, 2005.

D. R. Morris, A. J. Rodriguez, J. V. Moxon, M. A. Cunningham, M. M. Mcdermott et al., Association of lower extremity performance with cardiovascular and all-cause mortality in patients with peripheral artery disease: a systematic review and meta-analysis, J. Am. Heart Assoc, vol.3, 2014.

L. Omarjee, Vascular Pharmacology, vol.118, p.106563, 2019.