V. G. Allfrey, R. Faulkner, and A. E. Mirsky, Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis, Proc. Natl Acad. Sci. U.S.A, vol.51, pp.786-794, 1964.

L. Hong, G. P. Schroth, H. R. Matthews, P. Yau, and E. M. Bradbury, Studies of the DNA binding properties of histone H4 amino terminus. Thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 "tail" to DNA, J. Biol. Chem, vol.268, pp.305-314, 1993.

V. G. Norton, B. S. Imai, P. Yau, and E. M. Bradbury, Histone acetylation reduces nucleosome core particle linking number change, Cell, vol.57, pp.449-457, 1989.

D. Y. Lee, J. J. Hayes, D. Pruss, and A. P. Wolffe, A positive role for histone acetylation in transcription factor access to nucleosomal DNA, Cell, vol.72, pp.73-84, 1993.

D. Llères, J. James, S. Swift, D. G. Norman, and A. I. Lamond, Quantitative analysis of chromatin compaction in living cells using FLIM-FRET, J. Cell Biol, vol.187, pp.481-496, 2009.

M. Shogren-knaak, H. Ishii, J. M. Sun, M. J. Pazin, J. R. Davie et al., Histone H4-K16 acetylation controls chromatin structure and protein interactions, Science, vol.311, pp.844-847, 2006.

K. Sasaki, T. Ito, N. Nishino, S. Khochbin, and M. Yoshida, Real-time imaging of histone H4 hyperacetylation in living cells, Proc. Natl Acad. Sci. U.S.A, vol.106, pp.16257-16262, 2009.

D. A. Potoyan and G. A. Papoian, Regulation of the H4 tail binding and folding landscapes via Lys-16 acetylation, Proc. Natl Acad. Sci. U.S.A, vol.109, pp.17857-17862, 2012.

H. Weintraub, High-resolution mapping of S1-and DNase I-hypersensitive sites in chromatin, Mol. Cell Biol, vol.5, pp.1538-1539, 1985.

M. Tsompana and M. J. Buck, Chromatin accessibility: a window into the genome, Epigenet. Chromatin, vol.7, pp.33-49, 2014.

S. L. Klemm, Z. Shipony, and W. J. Greenleaf, Chromatin accessibility and the regulatory epigenome, Nat. Rev. Genet, vol.20, pp.207-220, 2019.

X. Chen, Y. Shen, W. Draper, J. D. Buenrostro, U. Litzenburger et al., ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing, Nat. Methods, vol.13, pp.1013-1020, 2016.

R. D. Phair and T. Misteli, High mobility of proteins in the mammalian cell nucleus, Nature, vol.404, pp.604-609, 2000.

S. M. Görisch, M. Wachsmuth, K. F. Tóth, P. Lichter, and K. Rippe, Histone acetylation increases chromatin accessibility, J. Cell Sci, vol.118, pp.5825-5834, 2005.

L. Schmiedeberg, K. Weisshart, S. Diekmann, G. Meyer-zu-hoerste, and P. Hemmerich, High-and low-mobility populations of HP1 in heterochromatin of mammalian cells, Mol. Biol. Cell, vol.15, pp.2819-2833, 2004.

E. Hinde, F. Cardarelli, and E. Gratton, Spatiotemporal regulation of Heterochromatin Protein 1-alpha oligomerization and dynamics in live cells, Sci. Rep, vol.5, pp.12001-12011, 2015.

E. Hinde, F. Cardarelli, M. A. Digman, and E. Gratton, In vivo pair correlation analysis of EGFP intranuclear diffusion reveals DNA-dependent molecular flow, Proc. Natl. Acad. Sci. U.S.A, vol.107, pp.16560-16565, 2010.

S. T. Spagnol and K. Dahl, Active cytoskeletal force and chromatin condensation independently modulate intranuclear network fluctuations, Integr. Biol, vol.6, pp.523-531, 2014.

V. Levi, Q. Ruan, M. Plutz, A. S. Belmont, and E. Gratton, Chromatin dynamics in interphase cells revealed by tracking in a Two-Photon excitation microscope, Biophys. J, vol.89, pp.4275-4285, 2005.

S. Hihara, C. G. Pack, K. Kaizu, T. Tani, T. Hanafusa et al., Local nucleosome dynamics facilitate chromatin accessibility in living mammalian cells, Cell Rep, vol.2, pp.1645-1656, 2012.

A. Zidovska, D. A. Weitz, and T. J. Mitchison, Micron-scale coherence in interphase chromatin dynamics, Proc. Natl Acad. Sci. U.S.A, vol.110, pp.15555-15560, 2013.

T. Nozaki, R. Imai, M. Tanbo, R. Nagashima, S. Tamura et al., Dynamic organization of chromatin domains revealed by super-resolution live-cell imaging, Mol. Cell, vol.67, pp.282-293, 2017.

M. Tramier, K. Kemnitz, C. Durieux, J. Coppey, P. Denjean et al., Restrained torsional dynamics of nuclear DNA in living proliferative mammalian cells, Biophys. J, vol.78, pp.2614-2627, 2000.

T. Kanno, Y. Kanno, R. M. Siegel, M. K. Jang, M. J. Lenardo et al., Selective recognition of acetylated histones by bromodomain proteins visualized in living cells, Mol. Cell, vol.13, pp.33-43, 2004.

S. Padilla-parra, N. Audugé, M. Coppey-moisan, and M. Tramier, Quantitative FRET analysis by fast acquisition time domain FLIM at high spatial resolution in living cells, Biophys. J, vol.95, pp.2976-2988, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00289731

F. Jeanmougin, J. Wurtz, B. Le-douarin, P. Chambon, and R. Losson, The bromodomain revisited, Trends Biochem. Sci, vol.22, pp.151-153, 1997.

P. Filippakopoulos, S. Picaud, M. Mangos, T. Keates, J. Lambert et al., Histone recognition and Large-Scale structural analysis of the human bromodomain family, Cell, vol.149, pp.214-231, 2012.

T. Förster, Zwischenmolekulare Energiewanderung und Fluoreszenz, Ann. Phys, vol.437, pp.55-75, 1948.

S. J. Strickler and R. A. Berg, Relationship between absorption intensity and fluorescence lifetime of molecules, J. Chem. Phys, vol.37, pp.814-822, 1962.

K. Suhling, J. Siegel, D. Phillips, P. M. French, S. Lévêque-fort et al., Imaging the environment of green fluorescent protein, Biophys. J, vol.83, pp.3589-3595, 2002.

S. Padilla-parra, N. Audugé, M. Coppey-moisan, and M. Tramier, Dual-color fluorescence lifetime correlation spectroscopy to quantify protein-protein interactions in live cell, Microsc. Res. Tech, vol.74, pp.788-793, 2011.
URL : https://hal.archives-ouvertes.fr/inserm-00604664

A. Brunsting and P. F. Mullaney, Differential light scattering from spherical mammalian cells, Biophys. J, vol.14, pp.439-453, 1974.

H. Van-manen, P. Verkuijlen, P. Wittendorp, V. Subramaniam, . Van-den et al., Refractive index sensing of green fluorescent proteins in living cells using fluorescence lifetime imaging microscopy, Biophys. J, vol.94, pp.67-69, 2008.

B. Treanor, P. M. Lanigan, K. Suhling, T. Schreiber, I. Munro et al., Imaging fluorescence lifetime heterogeneity applied to GFP-tagged MHC protein at an immunological synapse, J. Microsc, vol.217, pp.36-43, 2005.

R. H. Jacobson, A. G. Ladurner, D. S. King, and R. Tjian, Structure and function of a human TAFII250 double bromodomain module, Science, vol.288, pp.1422-1425, 2000.

M. Bohn, P. Diesinger, R. Kaufmann, Y. Weiland, P. Müller et al., Localization microscopy reveals expression-dependent parameters of chromatin nanostructure, Biophys. J, vol.99, pp.1358-1367, 2010.

M. A. Ricci, C. Manzo, M. F. García-parajo, M. Lakadamyali, and M. P. Cosma, Chromatin fibers are formed by heterogeneous groups of nucleosomes in vivo, Cell, vol.160, pp.1145-1158, 2015.

T. Weidemann, M. Wachsmuth, T. A. Knoch, G. Müller, W. Waldeck et al., Counting nucleosomes in living cells with a combination of fluorescence correlation spectroscopy and confocal imaging, J. Mol. Biol, vol.334, pp.229-240, 2003.

G. Li, M. Levitus, C. Bustamante, and J. Widom, Rapid spontaneous accessibility of nucleosomal DNA, Nat. Struct. Mol. Biol, vol.12, pp.46-53, 2005.

T. T. Ngo and T. Ha, Nucleosomes undergo slow spontaneous gaping, Nucleic Acids Res, vol.43, pp.3964-3971, 2015.

M. G. Poirier, E. Oh, H. S. Tims, and J. Widom, Dynamics and function of compact nucleosome arrays, Nat. Struct. Mol. Biol, vol.16, pp.938-944, 2009.

C. Lungu, K. Muegge, A. Jeltsch, and R. Z. Jurkowska, An ATPase-Deficient variant of the SNF2 family member HELLS shows altered dynamics at Pericentromeric heterochromatin, J. Mol. Biol, vol.427, pp.1903-1915, 2015.

R. Margueron and D. Reinberg, Chromatin structure and the inheritance of epigenetic information, Nat. Rev. Genet, vol.11, pp.285-296, 2010.

M. Doiguchi, T. Nakagawa, Y. Imamura, M. Yoneda, M. Higashi et al., SMARCAD1 is an ATP-dependent stimulator of nucleosomal H2A acetylation via CBP, resulting in transcriptional regulation, Sci. Rep, vol.6, pp.20179-20191, 2016.

S. A. Denslow and P. A. Wade, The human Mi-2/NuRD complex and gene regulation, Oncogene, vol.26, pp.5433-5438, 2007.

O. Bell, V. K. Tiwari, N. H. Thomä, and D. Schübeler, Determinants and dynamics of genome accessibility, Nat. Rev. Genet, vol.12, pp.554-564, 2011.

A. Bancaud, S. Huet, N. Daigle, J. Mozziconacci, J. Beaudouin et al., Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin, EMBO J, vol.28, pp.3785-3798, 2009.

A. N. Boettiger, B. Bintu, J. R. Moffitt, S. Wang, B. J. Beliveau et al., Super-resolution imaging reveals distinct chromatin folding for different epigenetic states, Nature, vol.529, pp.418-422, 2016.

T. Takizawa, K. J. Meaburn, and T. Misteli, The meaning of gene positioning, Cell, vol.135, pp.9-13, 2008.