Practical guide to quantification of hepatic iron with MRI

Abstract : Our intention is to demystify the MR quantification of hepatic iron (i.e., the liver iron concentration) and give you a step-by-step approach by answering the most pertinent questions. The following article should be more of a manual or guide for every radiologist than a classic review article, which just summarizes the literature. Furthermore, we provide important background information for professional communication with clinicians. The information regarding the physical background is reduced to a minimum. After reading this article, you should be able to perform adequate MR measurements of the LIC with 1.5-T or 3.0-T scanners. KEY POINTS • MRI is widely accepted as the primary approach to non-invasively determine liver iron concentration (LIC). • This article is a guide for every radiologist to perform adequate MR measurements of the LIC. • When using R2* relaxometry, some points have to be considered to obtain correct measurements-all explained in this article.
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Contributor : Laurent Jonchère <>
Submitted on : Friday, September 6, 2019 - 11:04:21 AM
Last modification on : Tuesday, September 10, 2019 - 2:15:48 PM

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Benjamin Henninger, Jose Alustiza, Maciej Garbowski, Yves Gandon. Practical guide to quantification of hepatic iron with MRI. European Radiology, 2019, ⟨10.1007/s00330-019-06380-9⟩. ⟨hal-02280257⟩

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