AlCl3-promoted reaction of cycloalkanones with hydrazones: a convenient direct synthesis of 4,5,6,7-tetrahydro-1H-indazoles and their analogues

Rima Laroum 1 Fabienne Berrée 2 Thierry Roisnel 2 Vincent Dorcet 2 Bertrand Carboni 2 Abdelmadjid Debache 1
1 UMC - Université Mentouri Constantine [Algérie]
2 ISCR - Institut des Sciences Chimiques de Rennes
Abstract : The AlCl3-promoted reactions of cycloalkanones with hydrazones are described. This approach represents a mild and operationally simple method to access 2,3-diaryl-4,5,6,7-tetrahydro-1H-indazoles and their analogues in good to moderate yields. (C) 2019 Elsevier Ltd. All rights reserved.
Keywords : Hydrazones Tetrahydroindazoles Aluminum chloride Cycloalkanones
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Journal articles
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https://hal-univ-rennes1.archives-ouvertes.fr/hal-02303397
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Submitted on : Wednesday, October 2, 2019 - 11:52:05 AM
Last modification on : Thursday, October 3, 2019 - 1:22:45 AM

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Rima Laroum, Fabienne Berrée, Thierry Roisnel, Vincent Dorcet, Bertrand Carboni, et al.. AlCl3-promoted reaction of cycloalkanones with hydrazones: a convenient direct synthesis of 4,5,6,7-tetrahydro-1H-indazoles and their analogues. Tetrahedron Letters, Elsevier, 2019, 60 (35), ⟨10.1016/j.tetlet.2019.150988⟩. ⟨hal-02303397⟩

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