AlCl3-promoted reaction of cycloalkanones with hydrazones: a convenient direct synthesis of 4,5,6,7-tetrahydro-1H-indazoles and their analogues

Rima Laroum; Fabienne Berrée; Thierry Roisnel; Vincent Dorcet; Bertrand Carboni; Abdelmadjid Debache

doi:10.1016/j.tetlet.2019.150988

Journal articles

AlCl3-promoted reaction of cycloalkanones with hydrazones: a convenient direct synthesis of 4,5,6,7-tetrahydro-1H-indazoles and their analogues

Rima Laroum ¹ Fabienne Berrée ² Thierry Roisnel ² Vincent Dorcet ² Bertrand Carboni ² Abdelmadjid Debache ^{1, *}

* Corresponding author

1 UMC - Université Mentouri Constantine [Algérie]

2 ISCR - Institut des Sciences Chimiques de Rennes

Abstract : The AlCl3-promoted reactions of cycloalkanones with hydrazones are described. This approach represents a mild and operationally simple method to access 2,3-diaryl-4,5,6,7-tetrahydro-1H-indazoles and their analogues in good to moderate yields. (C) 2019 Elsevier Ltd. All rights reserved.

Keywords : Aluminum chloride Cycloalkanones Tetrahydroindazoles Hydrazones

Domain :

Chemical Sciences

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AlCl3-promoted reaction of cycloalkanones with hydrazones: a convenient direct synthesis of 4,5,6,7-tetrahydro-1H-indazoles and their analogues

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AlCl3-promoted reaction of cycloalkanones with hydrazones: a convenient direct synthesis of 4,5,6,7-tetrahydro-1H-indazoles and their analogues

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