The role of poly ADP-ribosylation in the first wave of DNA damage response, Nucleic Acids Res, vol.45, pp.8129-8141, 2017. ,
Bovine thymus poly(adenosine diphosphate ribose) polymerase. Physical properties and binding to DNA, J. Biol. Chem, vol.255, pp.6205-6211, 1980. ,
Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1, Science, vol.336, pp.728-732, 2012. ,
HPF1/C4orf27 is a PARP-1-interacting protein that regulates PARP-1 ADP-ribosylation activity, Mol. Cell, vol.62, pp.432-442, 2016. ,
Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler, Proc. Natl. Acad. Sci. U.S.A, vol.106, pp.13770-13774, 2009. ,
links CHD2-mediated chromatin expansion and H3.3 deposition to DNA repair by Non-homologous End-Joining, Mol. Cell, vol.61, pp.547-562, 2016. ,
Mechanistic insights into autoinhibition of the oncogenic chromatin remodeler ALC1, Mol. Cell, vol.68, pp.847-859, 2017. ,
Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal, Nature, vol.517, pp.223-226, 2015. ,
Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure, Proc. Natl. Acad. Sci. U.S.A, vol.79, pp.3423-3427, 1982. ,
URL : https://hal.archives-ouvertes.fr/hal-02371437
The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage, Mol. Biol. Cell, vol.27, pp.3791-3799, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01382426
A systematic analysis of factors localized to damaged chromatin reveals PARP-Dependent recruitment of transcription factors, Cell Rep, vol.11, pp.1486-1500, 2015. ,
Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins, J. Biol. Chem, vol.275, pp.40974-40980, 2000. ,
CHD3 and CHD4 recruitment and chromatin remodeling activity at DNA breaks is promoted by early poly(ADP-ribose)-dependent chromatin relaxation, Nucleic Acids Res, vol.46, pp.6087-6098, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01808772
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation, Nat. Struct. Mol. Biol, vol.16, pp.923-929, 2009. ,
A sensor for quantification of macromolecular crowding in living cells, Nat. Methods, vol.12, pp.227-229, 2015. ,
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA, Science, vol.311, pp.856-861, 2006. ,
Stable morphology, but dynamic internal reorganisation, of interphase human chromosomes in living cells, PLoS One, vol.5, p.11560, 2010. ,
Delineation of the protein module that anchors HMGN proteins to nucleosomes in the chromatin of living cells, Mol. Cell Biol, vol.28, pp.2872-2883, 2008. ,
Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin, EMBO J, vol.28, pp.3785-3798, 2009. ,
, , 2001.
, CCAAT/enhancer binding protein alpha assembles essential cooperating factors in common subnuclear domains, Mol. Endocrinol, vol.15, pp.1665-1676
Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins, Biophys. J, vol.90, pp.1878-1894, 2006. ,
Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4, EMBO J, vol.29, pp.3130-3139, 2010. ,
The N-terminal region of chromodomain helicase DNA-binding Protein 4 (CHD4) is essential for activity and contains a high mobility group (HMG) Box-like-domain that can bind Poly(ADP-ribose), J. Biol. Chem, vol.291, pp.924-938, 2016. ,
Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain, Hum. Mol. Genet, vol.17, pp.3459-3473, 2008. ,
Near-infrared fluorescent proteins for multicolor in vivo imaging, Nat. Methods, vol.10, pp.751-754, 2013. ,
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes, Nature, vol.464, pp.721-727, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-01144034
CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter, Mol. Cell Biol, vol.16, pp.1231-1240, 1996. ,
MBD2 and multiple domains of CHD4 are required for transcriptional repression by Mi-2/NuRD complexes, Mol. Cell Biol, vol.32, pp.5078-5088, 2012. ,
Crowded chromatin is not sufficient for heterochromatin formation and not required for its maintenance, J. Struct. Biol, vol.184, pp.445-453, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-00878345
High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells, Nat. Biotechnol, vol.33, pp.384-389, 2015. ,
Poly(ADP-ribose)-dependent chromatin remodeling in DNA repair, Methods Mol. Biol, vol.1608, pp.165-183, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01579506
Direct measurement of association and dissociation rates of DNA binding in live cells by fluorescence correlation spectroscopy, Biophys. J, vol.97, pp.337-346, 2009. ,
Creating localized DNA double-strand breaks with microirradiation, Nat. Protoc, vol.6, pp.134-139, 2011. ,
Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software, Bioinforma. Oxf. Engl, vol.27, pp.1179-1180, 2011. ,
Fiji: an open-source platform for biological-image analysis, Nat. Methods, vol.9, pp.676-682, 2012. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02616466
Crystal structure of the nucleosome core particle at 2.8 A resolution, Nature, vol.389, pp.251-260, 1997. ,
The energetics of HMG box interactions with DNA: thermodynamics of the DNA binding of the HMG box from mouse sox-5, J. Mol. Biol, vol.294, pp.997-1013, 1999. ,
Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior, Genes Dev, vol.17, pp.2060-2072, 2003. ,
Architecture of the high mobility group nucleosomal protein 2-nucleosome complex as revealed by methyl-based NMR, Proc. Natl. Acad. Sci. U.S.A, vol.108, pp.12283-12288, 2011. ,
Heterochromatin protein 1 is recruited to various types of DNA damage, J. Cell Biol, vol.185, pp.577-586, 2009. ,
Splicing regulates NAD metabolite binding to histone macroH2A, Nat. Struct. Mol. Biol, vol.12, pp.624-625, 2005. ,
Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination, 2012. ,
, Genes Dev, vol.26, pp.235-240
Role of poly(ADP-ribose) formation in DNA repair, Nature, vol.356, pp.356-358, 1992. ,
The multiple effects of molecular crowding in the cell nucleus: From molecular dynamics to the regulation of nuclear architecture, Nuclear Architecture and Dynamics. Translational Epigenetics, vol.2, pp.209-232, 2018. ,
Macromolecular crowding: qualitative and semiquantitative successes, quantitative challenges, Biochim. Biophys. Acta, vol.1649, pp.127-139, 2003. ,
Theoretical principles of transcription factor traffic on folded chromatin, Nat. Commun, vol.9, p.1740, 2018. ,
DNA-protein interactions and chromosome banding, Exp. Cell Res, vol.110, pp.251-262, 1977. ,
High-resolution mapping and characterization of open chromatin across the genome, Cell, vol.132, pp.311-322, 2008. ,
Nucleosome rearrangement in human chromatin during UV-induced DNA-reapir synthesis, Proc. Natl. Acad. Sci. U.S.A, vol.75, pp.4238-4241, 1978. ,
NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1, Cell, vol.119, pp.803-814, 2004. ,
Acetyltransferase p300 collaborates with chromodomain helicase DNA-binding protein 4 (CHD4) to facilitate DNA double-strand break repair, Mutagenesis, vol.31, pp.193-203, 2016. ,
The dMi-2 chromodomains are DNA binding modules important for ATP-dependent nucleosome mobilization, EMBO J, vol.21, pp.2430-2440, 2002. ,
HP1 promotes tumor suppressor BRCA1 functions during the DNA damage response, Nucleic Acids Res, vol.41, pp.5784-5798, 2013. ,
Single-molecule kinetic analysis of HP1-chromatin binding reveals a dynamic network of histone modification and DNA interactions, Nucleic Acids Res, vol.45, pp.10504-10517, 2017. ,
Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1, Science, vol.325, pp.1240-1243, 2009. ,
Real-time tracking of parental histones reveals their contribution to chromatin integrity following DNA damage, Mol. Cell, vol.64, pp.65-78, 2016. ,
Poly(ADP-ribosyl)ation-dependent Downloaded from, 2016. ,
, 21 11267 transient chromatin decondensation and histone displacement following laser microirradiation, Nucleic Acids Research, vol.47, pp.1789-1802, 2019.
Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sites, Proc. Natl. Acad. Sci. U.S.A, vol.107, pp.19873-19878, 2010. ,
Targeting chromatin remodelers: signals and search mechanisms, Biochim. Biophys. Acta, vol.1809, pp.497-508, 2011. ,
Dynamics of CRISPR-Cas9 genome interrogation in living cells, Science, vol.350, pp.823-826, 2015. ,
Probing the target search of DNA-binding proteins in mammalian cells using TetR as model searcher, Nat. Commun, vol.6, p.7357, 2015. ,
Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci, Science, vol.299, pp.560-562, 2003. ,
Poly(ADP-Ribose) Polymerase 1 Promotes the human heat shock response by facilitating heat shock transcription factor 1 Binding to DNA, Mol. Cell Biol, vol.38, p.51, 2018. ,
Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors, Oncogene, vol.30, pp.2135-2146, 2011. ,
SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling, Mol. Cell, vol.51, pp.454-468, 2013. ,
Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair, Nucleic Acids Res, vol.41, pp.3115-3129, 2013. ,
URL : https://hal.archives-ouvertes.fr/cea-02386162
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways, Nucleic Acids Res, vol.34, pp.6170-6182, 2006. ,
Protein dynamics in complex DNA lesions, Mol. Cell, vol.69, pp.1046-1061, 2018. ,
Homeodomain proteins directly regulate ATM kinase activity, Bricks for Molecular Machines FRI Stream, vol.24, pp.1471-1483, 2018. ,
DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin, Proc. Natl. Acad. Sci. U.S.A, vol.111, pp.9169-9174, 2014. ,
Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects, Cell Res, vol.18, pp.73-84, 2008. ,
Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose), Nat. Commun, vol.6, p.8088, 2015. ,
Activation of DNA damage response signaling by condensed chromatin, Cell Rep, vol.9, pp.1703-1717, 2014. ,
A macrohistone variant links dynamic chromatin compaction to BRCA1-dependent genome maintenance, Cell Rep, vol.8, pp.1049-1062, 2014. ,