Contrast-enhanced CT texture parameters as predictive markers of high-risk urodynamic features in adult patients with spina bifida - Archive ouverte HAL Access content directly
Journal Articles Urology Year : 2019

Contrast-enhanced CT texture parameters as predictive markers of high-risk urodynamic features in adult patients with spina bifida

(1) , (1) , (1, 2, 3) , (1) , (1) , (1, 3, 2) , (1) , (1) , (1, 3, 2) , (1, 3, 2) , (1) , (1) , (4) , (1) , (1, 3, 2)
1
2
3
4
Zine-Eddine Khene
Claire Richard
Anis Gasmi
  • Function : Author
  • PersonId : 1019399

Abstract

OBJECTIVE : To investigate computed tomography (CT) texture analysis of the bladder wall as a predictor of urodynamics findings in adult patient with spina bifida.METHODS : A single-center prospective trial was conducted from March 2015 to March 2017 including all consecutive adult spina bifida patients seen for urodynamic testing. A contrast-enhanced abdominal CT was systematically performed in all patients during the same visit. Texture features of the bladder wall related to the gray-level histogram and gray-level co-occurrence were evaluated on CT images. Multivariate analysis was performed to identify independent predictors of poor bladder compliance and detrusor overactivity among clinical and texture parameters.RESULTS : Fourty patients were included. The Lasso penalized logistic regression analysis identified 2 texture parameters as potential predictors of poor bladder compliance: Skewness (coefficient weight, -1.81) and S.1.1.SumVarnc (coefficient weight, -3.52). Multivariate logistic regression analysis confirmed skewness (odds ratio [confidence interval 95%] = 0.40 [0.14, 0.97], P = .04) as an independent predictor of poor bladder compliance. The Lasso penalized logistic regression analysis identified one texture parameters as potential predictor of detrusor overactivity: Kurtosis (coefficient weight, -3.52), which was confirmed in multivariate logistic regression analysis (odds ratio [confidence interval 95%] = 1.12 [1.01, 1.55], P = .02).CONCLUSION : Our findings demonstrate that CT texture analysis of the bladder wall might be an interesting tool to identify spina bifida patients with high risk urodynamic features.
Fichier principal
Vignette du fichier
Khene et al-2019-Contrast-enhanced CT texture parameters as predictive markers of high-risk.pdf (506.52 Ko) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

hal-02363655 , version 1 (09-12-2019)

Identifiers

Cite

Zine-Eddine Khene, Claire Richard, Juliette Hascoet, Anis Gasmi, Anna Goujon, et al.. Contrast-enhanced CT texture parameters as predictive markers of high-risk urodynamic features in adult patients with spina bifida. Urology, 2019, 134, pp.84-89. ⟨10.1016/j.urology.2019.09.023⟩. ⟨hal-02363655⟩
62 View
195 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More